Chemical Safety Data Sheet MSDS / SDS

Cresol

Revision Date:2026-03-21Revision Number:1

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier

  • Product name: Cresol
  • CBnumber: CB5853043
  • CAS: 1319-77-3
  • EINECS Number: 215-293-2
  • Synonyms: CRESYLIC ACID;Cresols

Relevant identified uses of the substance or mixture and uses advised against

  • Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
  • Uses advised against: none

Company Identification

  • Company: Chemicalbook
  • Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
  • Telephone: 010-86108875

SECTION 2: Hazards identification

GHS Label elements, including precautionary statements

  • Symbol(GHS)
  • Signal wordDanger
Precautionary statements
P202 Do not handle until all safety precautions have been read and understood.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
Hazard statements
H314 Causes severe skin burns and eye damage
H341 Suspected of causing genetic defects
H412 Harmful to aquatic life with long lasting effects

SECTION 3: Composition/information on ingredients

Substance

  • Product name: Cresol
  • Synonyms: CRESYLIC ACID;Cresols
  • CAS: 1319-77-3
  • EC number: 215-293-2
  • MF: C7H8O
  • MW: 108.14

SECTION 4: First aid measures

General advice

First aiders need to protect themselves. Show this safety data sheet to the doctor in attendance.

If inhaled

After inhalation: fresh air. Call in physician.

In case of skin contact

After contact with skin: rinse out with polyethylene glycol 400 or a mixture of polyethylene glycol 300/ethanol 2:1 and wash with plenty of water. If neither is available wash with plenty of water. Immediately take off contaminated clothing. Call a physician immediately.

In case of eye contact

After eye contact: rinse out with plenty of water. Immediately call in ophthalmologist. Remove contact lenses.

If swallowed

If swallowed: give water to drink (two glasses at most). Seek medical advice immediately. In exceptional cases only, if medical care is not available within one hour, induce vomiting (only in persons who are wide awake and fully conscious), administer activated charcoal (20 - 40 g in a 10% slurry) and consult a doctor as quickly as possible. Do not attempt to neutralise.

Most important symptoms and effects, both acute and delayed

The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11

Protection of first-aiders

For personal protection see section 8.

Notes to physician

No data available

SECTION 5: Firefighting measures

Suitable extinguishing media

Water Foam Carbon dioxide (CO2) Dry powder

Unsuitable extinguishing media

For this substance/mixture no limitations of extinguishing agents are given.

Specific hazards during fire fighting

Combustible. Vapours are heavier than air and may spread along floors. Forms explosive mixtures with air on intense heating. Development of hazardous combustion gases or vapours possible in the event of fire.

Hazardous combustion products

Carbon oxides

Specific extinguishing methods

Remove container from danger zone and cool with water. Prevent fire extinguishing water from contaminating surface water or the ground water system.

Special protective equipment for fire-fighters

Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.

NFPA 704

3
2
0
HEALTH 3 Short exposure could cause serious temporary or moderate residual injury (e.g. liquid hydrogen, sulfuric acid, calcium hypochlorite, hexafluorosilicic acid)
FIRE 2 Must be moderately heated or exposed to relatively high ambient temperature before ignition can occur and multiple finely divided suspended solids that do not require heating before ignition can occur. Flash point between 37.8 and 93.3 °C (100 and 200 °F). (e.g. diesel fuel, sulfur)
REACT 0 Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2)
SPEC. HAZ.

SECTION 6: Accidental release measures

Personal precautions, protective equipment and emergency procedures

Advice for non-emergency personnel: Do not breathe vapours, aerosols. Avoid substance contact. Ensure adequate ventilation. Keep away from heat and sources of ignition. Evacuate the danger area, observe emergency procedures, consult an expert. Advice for emergency responders: For personal protection see section 8.

Environmental precautions

Do not let product enter drains.

Methods and materials for containment and cleaning up

Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up carefully with liquid-absorbent material . Dispose of properly. Clean up affected area.

SECTION 7: Handling and storage

Handling

Advice on protection against fire and explosion
Keep away from open flames, hot surfaces and sources of ignition. Take precautionary measures against static discharge.
Avoidance of contact
Strong oxidizing agents

Storage

Further information on storage conditions
Tightly closed. Keep in a well-ventilated place. Keep locked up or in an area accessible only to qualified or authorised persons.
Storage class
6.1A, Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
Recommended storage
Recommended storage temperature see product label. temperature
Further information on storage stability
Light sensitive. Air sensitive.

SECTION 8: Exposure controls/personal protection

Ingredients with workplace control parameters

Biological occupational exposure limits

Engineering measures

No data available

Personal protective equipment

Respiratory protection
required when vapours/aerosols are generated.
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Recommended Filter type
Filter type ABEK
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.
Eye/face protection
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Tightly fitting safety goggles
Skin and body protection
protective clothing
Hand protection
Material
Chloroprene
Break through time
480 min
Glove thickness
0.6 mm
Protective index
Full contact
Manufacturer
Camapren® (KCL 722 / Aldrich Z677493, Size M)
Material
Nitrile rubber
Break through time
30 min
Glove thickness
0.2 mm
Protective index
Splash contact
Manufacturer
P (KCL 743 / Aldrich Z677388, Size M)
Manufacturer
data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail sales@kcl.de, test method: EN374
Remarks
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.
The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it.
If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario.
Hygiene measures
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.

SECTION 9: Physical and chemical properties

Information on basic physicochemical properties

  • Physical stateclear liquid
  • Dielectric constant9.0(Ambient)
  • Appearanceliquid
  • ColorColorless to Almost colorless
  • OdorSweet, tarry.
  • Odor ThresholdNo data available
  • pHNo data available
  • Melting point/ rangeNo data available
  • Boiling point/boiling range192 - 201 °C
  • Flash point80 °C
    Method: closed cup
  • Evaporation rateNo data available
  • Flammability (solid, gas)No data available
  • Flammability (liquids)No data available
  • Burning rateNo data available
  • Upper explosion limit / Upper flammability limitNo data available
  • Lower explosion limit / Lower flammability limitNo data available
  • Vapor pressureNo data available
  • Relative vapor densityNo data available
  • Relative density1.04
  • Density1.042 g/cm3
  • Water solubility1.932 g/100 mL
  • Partition coefficient: n-octanol/waterNo data available
  • Autoignition temperatureNo data available
  • Decomposition temperatureNo data available
  • Viscosity, dynamicNo data available
  • Viscosity, kinematicNo data available
  • Flow timeNo data available
  • Explosive propertiesNot classified as explosive.
  • Oxidizing propertiesnone
  • Particle characteristics Particle sizeNo data available

SECTION 10: Stability and reactivity

Reactivity

Forms explosive mixtures with air on intense heating. A range from approx. 15 Kelvin below the flash point is to be rated as critical.

Chemical stability

The product is chemically stable under standard ambient conditions (room temperature) .

Possibility of hazardous reactions

No data available

Conditions to avoid

Air Strong heating.

Incompatible materials

Strong oxidizing agents

Hazardous decomposition products

In the event of fire: see section 5

SECTION 11: Toxicological information

11.1 Information on toxicological effects

Mixture Acute toxicity
Acute toxicity estimate Oral - 100.01 mg/kg (Calculation method)
Symptoms: If ingested, severe burns of the mouth and throat, as well as a danger of perforation of the oesophagus and the stomach.
Acute toxicity estimate Inhalation - 4 h - 7.29 mg/l - dust/mist(Calculation meth- od)
Symptoms: mucosal irritations, Cough, Shortness of breath, Possible damages:, damage of respiratory tract
Acute toxicity estimate Dermal - 311.91 mg/kg (Calculation method)
Skin corrosion/irritation
Remarks: Mixture causes burns.
Serious eye damage/eye irritation
Remarks: Mixture causes serious eye damage.
Risk of blindness!
Respiratory or skin sensitization
Classified based on available data. For more details, see section 2
Germ cell mutagenicity
Evidence of genetic defects.
Carcinogenicity
Classified based on available data. For more details, see section 2
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Classified based on available data. For more details, see section 2
Specific target organ toxicity - repeated exposure
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2

11.2 Additional Information

Material is extremely destructive to tissue of the mucous membranes and upper respiratory tract, eyes, and skin., spasm, inflammation and edema of the larynx, spasm, inflammation and edema of the bronchi, pneumonitis, pulmonary edema, burning sensation, Cough, wheezing, laryngitis, Shortness of breath, Headache,
Nausea
Other dangerous properties can not be excluded.
This substance should be handled with particular care.
Handle in accordance with good industrial hygiene and safety practice.
Components Cresol
Acute toxicity
Oral: No data available
Inhalation: No data available
LD50 Dermal - 300 mg/kg
Skin corrosion/irritation
Remarks: No data available
Serious eye damage/eye irritation
Remarks: No data available
Respiratory or skin sensitization
Classified based on available data. For more details, see section 2
Germ cell mutagenicity
Classified based on available data. For more details, see section 2
Carcinogenicity
Classified based on available data. For more details, see section 2
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Classified based on available data. For more details, see section 2
Specific target organ toxicity - repeated exposure
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2
Phenol
Acute toxicity
Acute toxicity estimate Oral - 100.1 mg/kg (Expert judgement)
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Acute toxicity estimate Inhalation - 4 h - 0.51 mg/l - dust/mist (Expert judgement)
Symptoms: Irritation, Lung oedema
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
LD50 Dermal - Rat - female - 660 mg/kg (OECD Test Guideline 402)
Skin corrosion/irritation
Skin - In vitro study
Result: Causes burns.
(OECD Test Guideline 431)
Serious eye damage/eye irritation
Eyes - Rabbit
Result: Corrosive (OECD Test Guideline 405)
Remarks: Causes serious eye damage.
Risk of blindness!
Respiratory or skin sensitization
Sensitisation test: - Guinea pig
Result: negative
Remarks: (IUCLID)
Germ cell mutagenicity
Suspected of causing genetic defects.
Test Type: Mutagenicity (mammal cell test): chromosome aberration.
Test system: Chinese hamster ovary cells
Result: positive
Test Type: Mutagenicity (mammal cell test): micronucleus.
Test system: Chinese hamster ovary cells
Result: positive
Carcinogenicity
This product is or contains a component that is not classifiable as to its car- cinogenicity based on its IARC, ACGIH, NTP, or EPA classification.
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Acute inhalation toxicity - Irritation, Lung oedema
Specific target organ toxicity - repeated exposure
May cause damage to organs through prolonged or repeated exposure.
- Nervous system, Kidney, Liver, Skin
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Aspiration hazard
Classified based on available data. For more details, see section 2

SECTION 12: Ecological information

Ecotoxicity

Components:

Phenol:

Toxicity to fish
LC50 (Onchorhynchus clarki): 8.9 mg/l Exposure time: 96 h Test Type: flow-through test Analytical monitoring: yes Method: US-EPA
Toxicity to daphnia and other aquatic invertebrates
EC50 (Ceriodaphnia dubia (water flea)): 3.1 mg/l End point: Immobilization Exposure time: 48 h Test Type: static test Analytical monitoring: yes Method: US-EPA
Toxicity to algae/aquatic plants
EC50 (Pseudokirchneriella subcapitata (algae)): 61.1 mg/l Exposure time: 96 h Test Type: static test Method: US-EPA
Toxicity to fish (Chronic toxicity)
NOEC (Fish): 0.077 mg/l Exposure time: 60 d Test Type: semi-static test Remarks: (ECHA)
Toxicity to daphnia and other aquatic invertebrates (Chronic toxicity)
NOEC (Daphnia magna (Water flea)): 0.16 mg/l End point: Growth inhibition Exposure time: 16 d Test Type: semi-static test Remarks: (ECHA)
Toxicity to microorganisms
IC50 (microorganisms): 21 mg/l Exposure time: 24 h Test Type: static test Remarks: (ECHA)

Persistence and degradability

Components:

Phenol:

Biodegradability
aerobic Inoculum: activated sludge Concentration: 100 mg/l Result: Readily biodegradable. Biodegradation: 62 % Exposure time: 100 h Method: OECD Test Guideline 301C

Bioaccumulative potential

Components:

Cresol:

Partition coefficient: noctanol/water
log Pow: 2.33 Method: OECD Test Guideline 117

Phenol:

Bioaccumulation
Species: Danio rerio (zebra fish) Bioconcentration factor (BCF): 17.5 Exposure time: 5 h Temperature: 25 °C Concentration: 2 mg/l Method: OECD Test Guideline 305 Remarks: Does not bioaccumulate.
Partition coefficient: noctanol/water
log Pow: 1.47 (30 °C) pH: 3 - 8 Remarks: (ECHA) Bioaccumulation is not expected.

Mobility in soil

Components:

Cresol:

Stability in soil
Remarks: No data available

Other adverse effects

Components:

Phenol:

Results of PBT and vPvB assessment
Substance does not meet the criteria for PBT or vPvB according to Regulation (EC) No 1907/2006, Annex XIII.

SECTION 13: Disposal considerations

Disposal methods

Waste from residues
Offer surplus and non-recyclable solutions to a licensed disposal company.

SECTION 14: Transport information

International Regulations

IATA-DGR

UN/ID No. : UN 2076
Proper shipping name : Cresols, liquid
Class : 6.1
Subsidiary risk : 8
Packing group : II
Labels : Division 6.1 - Toxic substances, Class 8 - Corrosive substances
Packing instruction (cargo aircraft) : 660
Packing instruction (passenger aircraft) : 653

IMDG-Code

UN number : UN 2076
Proper shipping name : CRESOLS, LIQUID
Class : 6.1
Subsidiary risk : 8
Packing group : II
Labels : 6.1 (8)
EmS Code : F-A, S-B
Marine pollutant : no

Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code

Not applicable for product as supplied.

National Regulations

JT/T 617

UN number : UN 2076
Proper shipping name : CRESOLS, LIQUID
Class : 6.1
Subsidiary risk : 8
Packing group : II
Labels : 6.1 (8)
Environmentally hazardous : no

Special precautions for user

The transport classification(s) provided herein are for informational purposes only, and solely based upon the properties of the unpackaged material as it is described within this Safety Data Sheet. Transportation classifications may vary by mode of transportation, package sizes, and variations in regional or country regulations.

SECTION 15: Regulatory information

National regulatory information

Law on the Prevention and Control of Occupational Diseases

Regulations on Safety Management of Hazardous Chemicals

Catalogue of Hazardous Chemicals

Listed

Identification of Major Hazard Installations for Hazardous Chemicals (GB 18218)

Not listed

Hazardous Chemicals for Priority Management

Listed under SAWS

Catalogue of Specially Controlled Hazardous

Not listed Chemicals

List of Explosive Precursors

Not listed

Regulations on Labour Protection in Workplaces where Toxic Substances are Used

Catalogue of Highly Toxic Chemicals

Not listed

Regulation of Environmental Management on the First Import of Chemicals and the Import and Export of Toxic Chemicals

China Severely Restricted Toxic Chemicals for Import and Export

Not listed

Regulation on the Administration of Precursor Chemicals

Catalogue and Classification of Precursor Chemicals

Not listed

Regulations on the Administration of Controlled Chemicals

List of Controlled Chemicals

Not listed

Regulations of Ozone Depleting Substances Management

List of Controlled Ozone Depleting Substances

Not listed

List of Controlled Ozone Depleting Substances Import and Export

Not listed

Environmental Protection Law

List of Priority Controlled Chemicals

Not listed

List of Key Controlled New Pollutants

Not listed

SECTION 16: Other information

Full text of other abbreviations

ACGIH
USA. ACGIH Threshold Limit Values (TLV)
ACGIH BEI
ACGIH - Biological Exposure Indices (BEI)
CN BEI
China. Biological Occupational Exposure Indices
GBZ 2.1-2007
Occupational exposure limits for hazardous agents in the workplace - Chemical hazardous agents.
ACGIH / TWA
8-hour, time-weighted average
GBZ 2.1-2007 / PC-TWA AIIC - Australian Invent Transport by Land of Bra bw - Body weight; CMR Standard of the German List (Canada); ECx - Conc associated with x% respo Chemical Substances (Jap response; ERG - Emerge GLP - Good Laboratory P cer; IATA - International Construction and Equipm Half maximal inhibitory c tion; IECSC - Inventory o tional Maritime Dangerou Industrial Safety and H Standardisation; KECI - K tration to 50 % of a test (Median Lethal Dose); MA lution from Ships; MERC of Dangerous Goods; n.o. - No Observed (Adverse) fect Level; NOELR - No Norm; NTP - National Toxi icals; OECD - Organisatio fice of Chemical Safety a and Toxic substance; PIC stances; (Q)SAR - (Quant (EC) No 1907/2006 of th Registration, Evaluation, Accelerating Decompositi Chemical Substance Inve Thailand Existing Chemica States); UN - United Nat Transport of Dangerous WHMIS - Workplace Hazar
Permissible concentration - time weighted average ry of Industrial Chemicals
ANTT - National Agency for il
ASTM - American Society for the Testing of Materials
- Carcinogen, Mutagen or Reproductive Toxicant
DIN nstitute for Standardisation
DSL - Domestic Substances ntration associated with x% response
ELx - Loading rate se
EmS - Emergency Schedule
ENCS - Existing and New n)
ErCx - Concentration associated with x% growth rate cy Response Guide
GHS - Globally Harmonised System
actice
IARC - International Agency for Research on Canir Transport Association
IBC - International Code for the nt of Ships carrying Dangerous Chemicals in Bulk
IC50 ncentration
ICAO - International Civil Aviation Organiza- Existing Chemical Substances in China
IMDG - Interna- Goods
IMO - International Maritime Organisation
ISHL alth Law (Japan)
ISO - International Organisation for rea Existing Chemicals Inventory
LC50 - Lethal Concenopulation
LD50 - Lethal Dose to 50% of a test population POL - International Convention for the Prevention of Pol- SUR - The Agreement for the Facilitation of the Transport . - Not Otherwise Specified
Nch - Chilean Norm
NO(A)EC ffect Concentration
NO(A)EL - No Observed (Adverse) Efbservable Effect Loading Rate
NOM - Official Mexican ology Program
NZIoC - New Zealand Inventory of Chemfor Economic Co-operation and Development
OPPTS - Ofd Pollution Prevention
PBT - Persistent, Bioaccumulative S - Philippines Inventory of Chemicals and Chemical Subtative) Structure Activity Relationship
REACH - Regulation European Parliament and of the Council concerning the uthorisation and Restriction of Chemicals
SADT - Selfn Temperature
SDS - Safety Data Sheet
TCSI - Taiwan tory
TDG - Transportation of Dangerous Goods
TECI s Inventory
TSCA - Toxic Substances Control Act (United ons
UNRTDG - United Nations Recommendations on the oods
vPvB - Very Persistent and Very Bioaccumulative
ous Materials Information System
Disclaimer:

The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.

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