11.1 Information on toxicological effects
Mixture Acute toxicity
Acute toxicity estimate Oral - 100.01 mg/kg (Calculation method)
Symptoms: If ingested, severe burns of the mouth and throat, as well as a danger of perforation of the oesophagus and the stomach.
Acute toxicity estimate Inhalation - 4 h - 7.29 mg/l - dust/mist(Calculation meth- od)
Symptoms: mucosal irritations, Cough, Shortness of breath, Possible damages:, damage of respiratory tract
Acute toxicity estimate Dermal - 311.91 mg/kg (Calculation method)
Skin corrosion/irritation
Remarks: Mixture causes burns.
Serious eye damage/eye irritation
Remarks: Mixture causes serious eye damage.
Risk of blindness!
Respiratory or skin sensitization
Classified based on available data. For more details, see section 2
Germ cell mutagenicity
Evidence of genetic defects.
Carcinogenicity
Classified based on available data. For more details, see section 2
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Classified based on available data. For more details, see section 2
Specific target organ toxicity - repeated exposure
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2
11.2 Additional Information
Material is extremely destructive to tissue of the mucous membranes and upper respiratory tract, eyes, and skin., spasm, inflammation and edema of the larynx, spasm, inflammation and edema of the bronchi, pneumonitis, pulmonary edema, burning sensation, Cough, wheezing, laryngitis, Shortness of breath, Headache,
Nausea
Other dangerous properties can not be excluded.
This substance should be handled with particular care.
Handle in accordance with good industrial hygiene and safety practice.
Components Cresol
Acute toxicity
Oral: No data available
Inhalation: No data available
LD50 Dermal - 300 mg/kg
Skin corrosion/irritation
Remarks: No data available
Serious eye damage/eye irritation
Remarks: No data available
Respiratory or skin sensitization
Classified based on available data. For more details, see section 2
Germ cell mutagenicity
Classified based on available data. For more details, see section 2
Carcinogenicity
Classified based on available data. For more details, see section 2
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Classified based on available data. For more details, see section 2
Specific target organ toxicity - repeated exposure
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2
Phenol
Acute toxicity
Acute toxicity estimate Oral - 100.1 mg/kg (Expert judgement)
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Acute toxicity estimate Inhalation - 4 h - 0.51 mg/l - dust/mist (Expert judgement)
Symptoms: Irritation, Lung oedema
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
LD50 Dermal - Rat - female - 660 mg/kg (OECD Test Guideline 402)
Skin corrosion/irritation
Skin - In vitro study
Result: Causes burns.
(OECD Test Guideline 431)
Serious eye damage/eye irritation
Eyes - Rabbit
Result: Corrosive (OECD Test Guideline 405)
Remarks: Causes serious eye damage.
Risk of blindness!
Respiratory or skin sensitization
Sensitisation test: - Guinea pig
Result: negative
Remarks: (IUCLID)
Germ cell mutagenicity
Suspected of causing genetic defects.
Test Type: Mutagenicity (mammal cell test): chromosome aberration.
Test system: Chinese hamster ovary cells
Result: positive
Test Type: Mutagenicity (mammal cell test): micronucleus.
Test system: Chinese hamster ovary cells
Result: positive
Carcinogenicity
This product is or contains a component that is not classifiable as to its car- cinogenicity based on its IARC, ACGIH, NTP, or EPA classification.
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Acute inhalation toxicity - Irritation, Lung oedema
Specific target organ toxicity - repeated exposure
May cause damage to organs through prolonged or repeated exposure.
- Nervous system, Kidney, Liver, Skin
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Aspiration hazard
Classified based on available data. For more details, see section 2