Chemical Safety Data Sheet MSDS / SDS
Methylamine
Revision Date:2026-03-21Revision Number:1
Product identifier
- Product name: Methylamine
- CBnumber: CB4387750
- CAS: 74-89-5
- EINECS Number: 200-820-0
- Synonyms: Methanamine;MeNH2
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 010-86108875
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233 Keep container tightly closed.
P240 Ground/bond container and receiving equipment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
Hazard statements
H225 Highly Flammable liquid and vapour
H314 Causes severe skin burns and eye damage
H335 May cause respiratory irritation
Substance
- Product name: Methylamine
- Synonyms: Methanamine;MeNH2
- CAS: 74-89-5
- EC number: 200-820-0
- MF: CH5N
- MW: 31.06
General advice
First aiders need to protect themselves. Show this safety data sheet to the doctor in attendance.
If inhaled
After inhalation: fresh air. Immediately call in physician. If breathing stops: immediately apply artificial respiration, if necessary also oxygen.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. Call a physician immediately.
In case of eye contact
After eye contact: rinse out with plenty of water. Immediately call in ophthalmologist. Remove contact lenses.
If swallowed
After swallowing: make victim drink water (two glasses at most), avoid vomiting (risk of perforation). Call a physician immediately. Do not attempt to neutralise.
Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11
Protection of first-aiders
For personal protection see section 8.
Notes to physician
No data available
Suitable extinguishing media
Water Foam Carbon dioxide (CO2) Dry powder
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.
Specific hazards during fire fighting
Mixture with combustible ingredients. Pay attention to flashback. Vapours are heavier than air and may spread along floors. Development of hazardous combustion gases or vapours possible in the event of fire. Forms explosive mixtures with air at ambient temperatures.
Hazardous combustion products Hazardous combustion products
Carbon oxides Nitrogen oxides (NOx) Carbon oxides Nitrogen oxides (NOx)
Specific extinguishing methods
Remove container from danger zone and cool with water. Suppress (knock down) gases/vapours/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.
Special protective equipment for fire-fighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
NFPA 704
3
4
0
| HEALTH | 3 | Short exposure could cause serious temporary or moderate residual injury (e.g. liquid hydrogen, sulfuric acid, calcium hypochlorite, hexafluorosilicic acid) | |
| FIRE | 4 | Will rapidly or completely vaporize at normal atmospheric pressure and temperature, or is readily dispersed in air and will burn readily. Includes pyrophoric substances. Flash point below room temperature at 22.8 °C (73 °F). (e.g. acetylene, propane, hydrogen gas) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Do not breathe vapours, aerosols. Avoid substance contact. Ensure adequate ventilation. Keep away from heat and sources of ignition. Evacuate the danger area, observe emergency procedures, consult an expert. Advice for emergency responders: For personal protection see section 8.
Environmental precautions
Do not let product enter drains. Risk of explosion.
Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up carefully with liquid-absorbent material . Dispose of properly. Clean up affected area.
Handling
Advice on protection against fire and explosionKeep away from open flames, hot surfaces and sources of ignition. Take precautionary measures against static discharge.
Advice on safe handling
Work under hood. Do not inhale substance/mixture. Avoid generation of vapours/aerosols.
Avoidance of contact
acids Acid chlorides Acid anhydrides Oxidizing agents Chloroformates Phosphorus halides
Storage
Further information on storage conditionsKeep container tightly closed in a dry and well- ventilated place. Keep away from heat and sources of ignition. Keep locked up or in an area accessible only to qualified or authorised persons.
Storage class
3, Flammable liquids
Recommended storage temperature
Recommended storage temperature see product label.
Packaging material
Suitable material: Amber Glass Bottle/Jar, Mild Steel Drum
control parameter
Hazard composition and occupational exposure limitsDoes not contain substances with occupational exposure limits.
Engineering measures
No data available
Personal protective equipment
Respiratory protectionrequired when vapours/aerosols are generated.
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Recommended Filter type
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Filter type AX
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.
Eye/face protection
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Tightly fitting safety goggles
Skin and body protection
Tightly fitting safety goggles
Flame retardant antistatic protective clothing.
Hand protection
Material
butyl-rubber
Break through time
480 min
Glove thickness
0.3 mm
Protective index
Full contact
Manufacturer
Butoject® (KCL 897 / Aldrich Z677647, Size M)
Material
Nitrile rubber
Break through time
60 min
Glove thickness
0.4 mm
Protective index
Splash contact
Manufacturer
Camatril® (KCL 730 / Aldrich Z677442, Size M)
Manufacturer
data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail sales@kcl.de, test method: EN374
Remarks
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.
The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it.
If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario.
Hygiene measures
The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it.
If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario.
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
Information on basic physicochemical properties
- Solubilityhighly soluble in water (108g/100g) at 25°C; soluble in alcohol and miscible with ether; HCl salt is soluble in water and absolute alcohol; compound is insoluble in chloroform, acetone, ether, and ethyl acetate
- Henry's Law Constant(x 10-5 atmm3/mol): 1.11 at 25 °C (Christie and Crisp, 1967)
- Physical stateGas
- Dielectric constant10.0（18℃）
- Particle characteristics Particle sizeNo data available
- Molecular weight31.06 g/mol
- Surface tension19.19 mN/m, 25 °C
- Oxidizing propertiesNo data available
- Explosive propertiesNo data available
- Flow timeNo data available
- Viscosity, kinematicNo data available
- Viscosity, dynamicNo data available
- Decomposition temperatureNo data available
- Autoignition temperature425 °C
- Partition coefficient: n-octanol/waterlog Pow: -0.713
- Water solubilitysoluble
- Density0.897 g/mL (25 °C)
- Relative density0.785 g/mL at 25 °C
- Relative vapor density1.07
- Vapor pressure371 hPa (20 °C)
- Lower explosion limit / Lower flammability limit5.2 %(V)
- Upper explosion limit / Upper flammability limit26.4 %(V)
- Burning rateNo data available
- Flammability (liquids)No data available
- Flammability (solid, gas)No data available
- Evaporation rateNo data available
- Flash point-10 °C
Method: closed cup - Boiling point/boiling range48 °C
- Melting point/ range-40 °C
- pH14.0
Concentration: 100 g/l - Odor ThresholdNo data available
- Odorunpleasant
- Colorcolourless
- Appearanceliquid
Reactivity
Vapours may form explosive mixture with air.
Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
Possibility of hazardous reactions
No data available
Conditions to avoid
Warming.
Incompatible materials
acids Acid chlorides Acid anhydrides Oxidizing agents Chloroformates Phosphorus halides
Hazardous decomposition products
In the event of fire: see section 5
11.1 Information on toxicological effects
Mixture Acute toxicityLD50 Oral - Rat - 698 mg/kg
Oral: No data available
Symptoms: If ingested, severe burns of the mouth and throat, as well as a danger of perforation of the oesophagus and the stomach.
LC50 Inhalation - Rat - 4 h - > 2.1 - < 2.9 mg/l - vapour
Symptoms: mucosal irritations, Cough, Shortness of breath, Possible damages:, damage of respiratory tract
Dermal: No data available
Skin corrosion/irritation
Oral: No data available
Symptoms: If ingested, severe burns of the mouth and throat, as well as a danger of perforation of the oesophagus and the stomach.
LC50 Inhalation - Rat - 4 h - > 2.1 - < 2.9 mg/l - vapour
Symptoms: mucosal irritations, Cough, Shortness of breath, Possible damages:, damage of respiratory tract
Dermal: No data available
Remarks: No data available
Remarks: Mixture causes burns.
Serious eye damage/eye irritation
Remarks: Mixture causes burns.
Remarks: No data available
Remarks: Mixture causes serious eye damage.
Risk of blindness!
Respiratory or skin sensitization
Remarks: Mixture causes serious eye damage.
Risk of blindness!
Classified based on available data. For more details, see section 2
Germ cell mutagenicity
Classified based on available data. For more details, see section 2
Carcinogenicity
Classified based on available data. For more details, see section 2
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Remarks: No data available
Mixture may cause respiratory irritation.
Specific target organ toxicity - repeated exposure
Mixture may cause respiratory irritation.
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2
11.2 Additional Information
Other dangerous properties can not be excluded.
Handle in accordance with good industrial hygiene and safety practice.
Components methylamine in solution
Handle in accordance with good industrial hygiene and safety practice.
Acute toxicity
LD50 Oral - Rat - male and female - 698 mg/kg (OECD Test Guideline 401)
Acute toxicity estimate Inhalation - 4 h - 11.1 mg/l - vapour (Expert judgement)
Dermal: No data available
Acute toxicity estimate Inhalation - 4 h - 11.1 mg/l - vapour (Expert judgement)
Dermal: No data available
Skin corrosion/irritation
Remarks: Causes severe burns.
Serious eye damage/eye irritation
Remarks: No data available
Respiratory or skin sensitization
Classified based on available data. For more details, see section 2
Germ cell mutagenicity
Test Type: Ames test
Test system: Salmonella typhimurium
Result: negative
Test Type: In vitro mammalian cell gene mutation test
Test system: Chinese hamster ovary cells
Result: negative
Method: OECD Test Guideline 474
Species: Mouse - male
Result: negative
Carcinogenicity
Test system: Salmonella typhimurium
Result: negative
Test Type: In vitro mammalian cell gene mutation test
Test system: Chinese hamster ovary cells
Result: negative
Method: OECD Test Guideline 474
Species: Mouse - male
Result: negative
Classified based on available data. For more details, see section 2
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Inhalation - May cause respiratory irritation. - Respiratory system, Stomach
Specific target organ toxicity - repeated exposure
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2
Ecotoxicity
Toxicity to fishRemarks: No data available
Components:
methylamine in solution:
Toxicity to fishRemarks: No data available
Toxicity to daphnia and other aquatic invertebrates
EC50 (Daphnia magna (Water flea)): 163 mg/l End point: Immobilization Exposure time: 48 h Test Type: static test Remarks: (ECHA)
Toxicity to algae/aquatic plants
ErC50 (Desmodesmus subspicatus (green algae)): > 281.8 mg/l Exposure time: 72 h Test Type: static test Analytical monitoring: yes Method: OECD Test Guideline 201 GLP: yes
Toxicity to microorgan- isms
EC20 (activated sludge): 240 mg/l Exposure time: 30 min Method: ISO 8192
Persistence and degradability
BiodegradabilityRemarks: No data available
Components:
methylamine in solution:
Biodegradabilityaerobic Inoculum: activated sludge Concentration: 100 mg/l Result: Readily biodegradable. Biodegradation: 84 % Exposure time: 14 d Method: OECD Test Guideline 301C
Bioaccumulative potential
BioaccumulationRemarks: No data available
Components:
methylamine in solution:
Partition coefficient: noctanol/waterlog Pow: -0.713 (25 °C) pH: 11.1 - 11.4 Method: OECD Test Guideline 107 Remarks: Bioaccumulation is not expected.
Mobility in soil
Stability in soilRemarks: No data available
Other adverse effects
No data available
Disposal methods
Waste from residuesOffer surplus and non-recyclable solutions to a licensed disposal company.
International Regulations
IATA-DGR
UN/ID No. : UN 1235
Proper shipping name : Methylamine, aqueous solution
Class : 3
Subsidiary risk : 8
Packing group : II
Labels : Class 3 - Flammable liquids, Class 8 - Corrosive substances
Packing instruction (cargo aircraft) : 363
Packing instruction (passenger aircraft) : 352
Proper shipping name : Methylamine, aqueous solution
Class : 3
Subsidiary risk : 8
Packing group : II
Labels : Class 3 - Flammable liquids, Class 8 - Corrosive substances
Packing instruction (cargo aircraft) : 363
Packing instruction (passenger aircraft) : 352
IMDG-Code
UN number : UN 1235
Proper shipping name : METHYLAMINE, AQUEOUS SOLUTION
Class : 3
Subsidiary risk : 8
Packing group : II
Labels : 3 (8)
EmS Code : F-E, S-C
Marine pollutant : no
Proper shipping name : METHYLAMINE, AQUEOUS SOLUTION
Class : 3
Subsidiary risk : 8
Packing group : II
Labels : 3 (8)
EmS Code : F-E, S-C
Marine pollutant : no
Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code
Not applicable for product as supplied.
National Regulations
JT/T 617
UN number : UN 1235
Proper shipping name : METHYLAMINE, AQUEOUS SOLUTION
Class : 3
Subsidiary risk : 8
Packing group : II
Labels : 3 (8)
Environmentally hazardous : no
Proper shipping name : METHYLAMINE, AQUEOUS SOLUTION
Class : 3
Subsidiary risk : 8
Packing group : II
Labels : 3 (8)
Environmentally hazardous : no
Special precautions for user
The transport classification(s) provided herein are for informational purposes only, and solely based upon the properties of the unpackaged material as it is described within this Safety Data Sheet. Transportation classifications may vary by mode of transportation, package sizes, and variations in regional or country regulations.
National regulatory information
Law on the Prevention and Control of Occupational Diseases
Regulations on Safety Management of Hazardous Chemicals
Catalogue of Hazardous Chemicals
Listed
Identification of Major Hazard Installations for Hazardous Chemicals (GB 18218)
No. / Code Chemical name / Category Threshold quantity
W5.3 Flammable liquids 1,000 t
Hazardous Chemicals for Priority Management
Listed under SAWS
Catalogue of Specially Controlled Hazardous
Not listed Chemicals
List of Explosive Precursors
Listed
Regulations on Labour Protection in Workplaces where Toxic Substances are Used
Catalogue of Highly Toxic Chemicals
Not listed
Regulation of Environmental Management on the First Import of Chemicals and the Import and Export of Toxic Chemicals
China Severely Restricted Toxic Chemicals for Import and Export
Not listed
Regulation on the Administration of Precursor Chemicals
Catalogue and Classification of Precursor Chemicals
Not listed
Regulations on the Administration of Controlled Chemicals
List of Controlled Chemicals
Not listed
Regulations of Ozone Depleting Substances Management
List of Controlled Ozone Depleting Substances
Not listed
List of Controlled Ozone Depleting Substances Import and Export
Not listed
Environmental Protection Law
List of Priority Controlled Chemicals
Not listed
List of Key Controlled New Pollutants
Not listed
Full text of other abbreviations
ACGIHUSA. ACGIH Threshold Limit Values (TLV)
GBZ 2.1-2007
Occupational exposure limits for hazardous agents in the workplace - Chemical hazardous agents.
ACGIH / TWA
8-hour, time-weighted average
ACGIH / STEL
Short-term exposure limit
GBZ 2.1-2007 / PC-TWA
Permissible concentration - time weighted average
GBZ 2.1-2007 / PC-STEL AIIC - Australian Invent Transport by Land of Bra bw - Body weight; CMR Standard of the German List (Canada); ECx - Conc associated with x% respo Chemical Substances (Jap response; ERG - Emerge GLP - Good Laboratory P cer; IATA - International Construction and Equipm Half maximal inhibitory c tion; IECSC - Inventory o tional Maritime Dangerou Industrial Safety and H Standardisation; KECI - K tration to 50 % of a test (Median Lethal Dose); MA lution from Ships; MERC of Dangerous Goods; n.o. - No Observed (Adverse) fect Level; NOELR - No Norm; NTP - National Toxi icals; OECD - Organisatio fice of Chemical Safety a and Toxic substance; PIC stances; (Q)SAR - (Quant (EC) No 1907/2006 of th Registration, Evaluation, Accelerating Decompositi Chemical Substance Inve Thailand Existing Chemica States); UN - United Nat Transport of Dangerous WHMIS - Workplace Hazar
Permissible concentration - short term exposure limit ry of Industrial Chemicals
ANTT - National Agency for il
ASTM - American Society for the Testing of Materials
- Carcinogen, Mutagen or Reproductive Toxicant
DIN nstitute for Standardisation
DSL - Domestic Substances ntration associated with x% response
ELx - Loading rate se
EmS - Emergency Schedule
ENCS - Existing and New n)
ErCx - Concentration associated with x% growth rate cy Response Guide
GHS - Globally Harmonised System
actice
IARC - International Agency for Research on Canir Transport Association
IBC - International Code for the nt of Ships carrying Dangerous Chemicals in Bulk
IC50 ncentration
ICAO - International Civil Aviation Organiza- Existing Chemical Substances in China
IMDG - Interna- Goods
IMO - International Maritime Organisation
ISHL alth Law (Japan)
ISO - International Organisation for rea Existing Chemicals Inventory
LC50 - Lethal Concenopulation
LD50 - Lethal Dose to 50% of a test population POL - International Convention for the Prevention of Pol- SUR - The Agreement for the Facilitation of the Transport . - Not Otherwise Specified
Nch - Chilean Norm
NO(A)EC ffect Concentration
NO(A)EL - No Observed (Adverse) Efbservable Effect Loading Rate
NOM - Official Mexican ology Program
NZIoC - New Zealand Inventory of Chem- for Economic Co-operation and Development
OPPTS - Ofd Pollution Prevention
PBT - Persistent, Bioaccumulative S - Philippines Inventory of Chemicals and Chemical Subtative) Structure Activity Relationship
REACH - Regulation European Parliament and of the Council concerning the uthorisation and Restriction of Chemicals
SADT - Selfn Temperature
SDS - Safety Data Sheet
TCSI - Taiwan tory
TDG - Transportation of Dangerous Goods
TECI s Inventory
TSCA - Toxic Substances Control Act (United ons
UNRTDG - United Nations Recommendations on the oods
vPvB - Very Persistent and Very Bioaccumulative
ous Materials Information System
ANTT - National Agency for il
ASTM - American Society for the Testing of Materials
- Carcinogen, Mutagen or Reproductive Toxicant
DIN nstitute for Standardisation
DSL - Domestic Substances ntration associated with x% response
ELx - Loading rate se
EmS - Emergency Schedule
ENCS - Existing and New n)
ErCx - Concentration associated with x% growth rate cy Response Guide
GHS - Globally Harmonised System
actice
IARC - International Agency for Research on Canir Transport Association
IBC - International Code for the nt of Ships carrying Dangerous Chemicals in Bulk
IC50 ncentration
ICAO - International Civil Aviation Organiza- Existing Chemical Substances in China
IMDG - Interna- Goods
IMO - International Maritime Organisation
ISHL alth Law (Japan)
ISO - International Organisation for rea Existing Chemicals Inventory
LC50 - Lethal Concenopulation
LD50 - Lethal Dose to 50% of a test population POL - International Convention for the Prevention of Pol- SUR - The Agreement for the Facilitation of the Transport . - Not Otherwise Specified
Nch - Chilean Norm
NO(A)EC ffect Concentration
NO(A)EL - No Observed (Adverse) Efbservable Effect Loading Rate
NOM - Official Mexican ology Program
NZIoC - New Zealand Inventory of Chem- for Economic Co-operation and Development
OPPTS - Ofd Pollution Prevention
PBT - Persistent, Bioaccumulative S - Philippines Inventory of Chemicals and Chemical Subtative) Structure Activity Relationship
REACH - Regulation European Parliament and of the Council concerning the uthorisation and Restriction of Chemicals
SADT - Selfn Temperature
SDS - Safety Data Sheet
TCSI - Taiwan tory
TDG - Transportation of Dangerous Goods
TECI s Inventory
TSCA - Toxic Substances Control Act (United ons
UNRTDG - United Nations Recommendations on the oods
vPvB - Very Persistent and Very Bioaccumulative
ous Materials Information System
Disclaimer:
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.
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