Chemical Safety Data Sheet MSDS / SDS
Ammonium hydrogen difluoride
Revision Date:2026-03-21Revision Number:1
Product identifier
- Product name: Ammonium hydrogen difluoride
- CBnumber: CB0273686
- CAS: 1341-49-7
- EINECS Number: 215-676-4
- Synonyms: AMMONIUM BIFLUORIDE;Ammonium Biflouride
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 010-86108875
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P270 Do not eat, drink or smoke when using this product.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
Hazard statements
H314 Causes severe skin burns and eye damage
H301 Toxic if swalloed
Substance
- Product name: Ammonium hydrogen difluoride
- Synonyms: AMMONIUM BIFLUORIDE;Ammonium Biflouride
- CAS: 1341-49-7
- EC number: 215-676-4
- MF: F2H5N
- MW: 57.04
General Advice
Show this safety data sheet to the doctor in attendance. Immediate medical attention is required.
Eye Contact
In the case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Skin Contact
Wash off immediately with plenty of water for at least 15 minutes. Immediate medical attention is required.
Inhalation
Remove to fresh air. If not breathing, give artificial respiration. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Immediate medical attention is required.
Ingestion
Do NOT induce vomiting. Call a physician or poison control center immediately.
Most important symptoms and effects
Causes burns by all exposure routes. Ingestion causes severe swelling, severe damage to the delicate tissue and danger of perforation: Product is a corrosive material. Use of gastric lavage or emesis is contraindicated. Possible perforation of stomach or esophagus should be investigated
Self-Protection of the First Aider
Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and prevent spread of contamination.
Notes to Physician
Treat symptomatically.
Suitable Extinguishing Media
Substance is nonflammable; use agent most appropriate to extinguish surrounding fire. CO2, dry chemical, dry sand, alcohol-resistant foam.
Extinguishing media which must not be used for safety reasons
No information available.
Specific Hazards Arising from the Chemical
The product causes burns of eyes, skin and mucous membranes.
Protective Equipment and Precautions for Firefighters
As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear. Thermal decomposition can lead to release of irritating gases and vapors.
NFPA 704
3
0
1
| HEALTH | 3 | Short exposure could cause serious temporary or moderate residual injury (e.g. liquid hydrogen, sulfuric acid, calcium hypochlorite, hexafluorosilicic acid) | |
| FIRE | 0 | Materials that will not burn under typical fire conditions, including intrinsically noncombustible materials such as concrete, stone, and sand. Materials that will not burn in air when exposed to a temperature of 820 °C (1,500 °F) for a period of 5 minutes.(e.g. Carbon tetrachloride) | |
| REACT | 1 | Normally stable, but can become unstable at elevated temperatures and pressures (e.g. propene) | |
| SPEC. HAZ. |
Personal Precautions
Use personal protective equipment as required. Evacuate personnel to safe areas. Ensure adequate ventilation. Keep people away from and upwind of spill/leak. Avoid dust formation.
Environmental Precautions
Should not be released into the environment.
Methods for Containment and Clean Up
Sweep up and shovel into suitable containers for disposal. Avoid dust formation.
Refer to protective measures listed in Sections 8 and 13.
Refer to protective measures listed in Sections 8 and 13.
Handling
Wear personal protective equipment/face protection. Do not get in eyes, on skin, or on clothing. Use only under a chemical fume hood. Do not ingest. If swallowed then seek immediate medical assistance. Do not breathe (dust, vapor, mist, gas). Avoid dust formation.
Storage
Keep containers tightly closed in a dry, cool and well-ventilated place. Air sensitive. Corrosives area. Store under an inert atmosphere.
Specific Use(s)
Use in laboratories
Control Parameters
| Component | China | Taiwan | Thailand | Hong Kong |
|---|---|---|---|---|
| Ammonium bifluoride | - | TWA: 2.5 mg/m3 | TWA: 2.5 mg/m3 | - |
| Component | ACGIH TLV | OSHA PEL | NIOSH | The United Kingdom | European Union |
|---|---|---|---|---|---|
| Ammonium bifluoride | TWA: 2.5 mg/m3 | (Vacated) TWA: 2.5 mg/m3 | IDLH: 250 mg/m3 REL = 2.5 mg/m3 (TWA) | STEL: 7.5 mg/m3 15 min TWA: 2.5 mg/m3 8 hr |
Legend
ACGIH
- American Conference of Governmental Industrial Hygienists
OSHA
- Occupational Safety and Health Administration
NIOSH
NIOSH - National Institute for Occupational Safety and Health
Monitoring methods
BS EN 14042:2003 Title Identifier: Workplace atmospheres. Guide for the application and use of procedures for the assessment of exposure to chemical and biological agents. MDHS14/3 General methods for sampling and gravimetric analysis of respirable and inhalable dust
Exposure Controls
Engineering Measures
Use only under a chemical fume hood. Ensure adequate ventilation, especially in confined areas. Ensure that eyewash stations and safety showers are close to the workstation location. Wherever possible, engineering control measures such as the isolation or enclosure of the process, the introduction of process or equipment changes to minimise release or contact, and the use of properly designed ventilation systems, should be adopted to control hazardous materials at source.
Personal protective equipment
Eye ProtectionGoggles (European standard - EN 166)
Hand Protection
Protective gloves
Inspect gloves before use.
Please observe the instructions regarding permeability and breakthrough time which are provided by the supplier of the gloves.
(Refer to manufacturer/supplier for information)
Ensure gloves are suitable for the task: Chemical compatability, Dexterity, Operational conditions, User susceptibility, e.g.
sensitisation effects, also take into consideration the specific local conditions under which the product is used, such as the danger of cuts, abrasion.
Remove gloves with care avoiding skin contamination.
Skin and body protection
| Glove material | Breakthrough time | Glove thickness | EU standard | Glove comments |
|---|---|---|---|---|
| Natural rubber | See manufacturers | - | EN 374 | (minimum requirement) |
| Nitrile rubber | recommendations | |||
| Neoprene | ||||
| PVC |
Inspect gloves before use.
Please observe the instructions regarding permeability and breakthrough time which are provided by the supplier of the gloves.
(Refer to manufacturer/supplier for information)
Ensure gloves are suitable for the task: Chemical compatability, Dexterity, Operational conditions, User susceptibility, e.g.
sensitisation effects, also take into consideration the specific local conditions under which the product is used, such as the danger of cuts, abrasion.
Remove gloves with care avoiding skin contamination.
Long sleeved clothing
Respiratory Protection
When workers are facing concentrations above the exposure limit they must use appropriate certified respirators.
To protect the wearer, respiratory protective equipment must be the correct fit and be used and maintained properly
Large scale/emergency use
To protect the wearer, respiratory protective equipment must be the correct fit and be used and maintained properly
Use a NIOSH/MSHA or European Standard EN 136 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced
Recommended Filter type: Particulates filter conforming to EN 143
Small scale/Laboratory use
Recommended Filter type: Particulates filter conforming to EN 143
Use a NIOSH/MSHA or European Standard EN 149:2001 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Recommended half mask:- Particle filtering: EN149:2001
When RPE is used a face piece Fit Test should be conducted
Recommended half mask:- Particle filtering: EN149:2001
When RPE is used a face piece Fit Test should be conducted
Hygiene Measures
Handle in accordance with good industrial hygiene and safety practice.
Environmental exposure controls
No information available.
Information on basic physicochemical properties
- ColourWhite
- Water Solubility630 g/L (20°C)
- Bulk Density1,5 g/cm3
- Specific Gravity / Density1.50
- Vapor DensityNot applicable Solid
- Vapor Pressure1 hPa @ 20 °C
- Explosion LimitsNo data available
- Flammability (solid,gas)No information available
- Evaporation RateNot applicable Solid
- Flash PointNo information available
Method - No information available - Boiling Point/Range230 °C / 446 °F @ 760 mmHg
- Softening PointNo data available
- Melting Point/Range125 °C / 257 °F
- pH3.5 5% aq. solution
- Odor ThresholdNo data available
- Odorpungent
- Physical StateSolid
- AppearanceWhite
- Molecular Weight57.04
- Molecular FormulaH5 F2 N
- Oxidizing PropertiesNo information available
- Explosive PropertiesNo information available
- ViscosityNot applicable Solid
- Decomposition Temperature> 230°C
- Autoignition TemperatureNo data available
- Partition Coefficient (n-octanol/water)No data available
- Solubility in other solvents630g/l
Stability
Hygroscopic.
Hazardous Reactions
None under normal processing.
Hazardous Polymerization
Hazardous polymerization does not occur.
Conditions to Avoid
Avoid dust formation. Incompatible products. Excess heat. Exposure to moisture. Exposure to moist air or water.
Materials to avoid
Strong acids. Strong bases.
Hazardous Decomposition Products
Hydrogen fluoride. Ammonia.
Product Information
(a) acute toxicity;
ComponentLD50 Oral LD50 Dermal LC50 Inhalation
(b) skin corrosion/irritation;
Category 1 B
(c) serious eye damage/irritation;
Category 1
(d) respiratory or skin sensitization;
Respiratory
No data available
Skin
No data available
(e) germ cell mutagenicity;
No data available
(f) carcinogenicity;
No data available
There are no known carcinogenic chemicals in this product
There are no known carcinogenic chemicals in this product
(g) reproductive toxicity;
No data available
(h) STOT-single exposure;
No data available
(i) STOT-repeated exposure;
No data available
Target Organs
None known.
(j) aspiration hazard;
Not applicable
Solid
Solid
Symptoms / effects,both acute and Ingestion causes severe swelling, severe damage to the delicate tissue and danger of
delayed
perforation: Product is a corrosive material. Use of gastric lavage or emesis is contraindicated. Possible perforation of stomach or esophagus should be investigated
Ecotoxicity effects
Do not empty into drains. .
Persistence and Degradability
Persistence
Soluble in water, Persistence is unlikely, based on information available.
Degradability
Not relevant for inorganic substances.
Bioaccumulative Potential
Bioaccumulation is unlikely
Mobility in soil
The product is water soluble, and may spread in water systems Will likely be mobile in the environment due to its water solubility Highly mobile in soils
Endocrine Disruptor Information
This product does not contain any known or suspected endocrine disruptors
Persistent Organic Pollutant
This product does not contain any known or suspected substance
Ozone Depletion Potential
This product does not contain any known or suspected substance
Waste from Residues/Unused Products
Waste is classified as hazardous. Dispose of in accordance with the European Directives on waste and hazardous waste. Dispose of in accordance with local regulations.
Contaminated Packaging
Dispose of this container to hazardous or special waste collection point.
Other Information
Waste codes should be assigned by the user based on the application for which the product was used. Do not empty into drains. Do not flush to sewer. Large amounts will affect pH and harm aquatic organisms.
Road and Rail Transport
UN-NoUN1727
Proper Shipping Name
AMMONIUM HYDROGENDIFLUORIDE, SOLID
Hazard Class
8
Packing Group
II
IMDG/IMO
UN-NoUN1727
Proper Shipping Name
AMMONIUM HYDROGENDIFLUORIDE, SOLID
Hazard Class
8
Packing Group
II
IATA
UN-NoUN1727
Proper Shipping Name
AMMONIUM HYDROGENDIFLUORIDE, SOLID
Hazard Class
8
Packing Group
II
Special Precautions for User
No special precautions required
International Inventories
China, X = listed, Australia, U.S.A. (TSCA), Canada (DSL/NDSL), Europe (EINECS/ELINCS/NLP), Australia (AICS), Korea (KECL), China (IECSC),
Japan (ENCS), Philippines (PICCS), Taiwan (TCSI), Japan (ISHL), New Zealand (NZIoC), Japan (ISHL).
Japan (ENCS), Philippines (PICCS), Taiwan (TCSI), Japan (ISHL), New Zealand (NZIoC), Japan (ISHL).
| Component | The Inventory of Hazardous Chemicals (2015 Edition) | List of dangerous goods GB 12268 - 2012 | TCSI | IECSC | EINECS | TSCA | DSL | PICCS | ENCS | ISHL | AICS | KECL |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ammonium bifluoride | X | X | X | X | 215-676-4 | X | X | X | X | X | X | KE-01679 |
National Regulations
Prepared By
Health, Safety and Environmental Department
Revision Summary
SDS sections updated.
Training Advice
Chemical hazard awareness training, incorporating labelling, Safety Data Sheets (SDS), Personal Protective Equipment (PPE) and hygiene.
Use of personal protective equipment, covering appropriate selection, compatibility, breakthrough thresholds, care, maintenance, fit and standards.
First aid for chemical exposure, including the use of eye wash and safety showers.
Use of personal protective equipment, covering appropriate selection, compatibility, breakthrough thresholds, care, maintenance, fit and standards.
First aid for chemical exposure, including the use of eye wash and safety showers.
Legend
CASChemical Abstracts Service
TSCA
United States Toxic Substances Control Act Section 8(b)
Inventory
EINECS/ELINCS
Inventory
European Inventory of Existing Commercial Chemical
Substances/EU List of Notified Chemical Substances
DSL/NDSL
Substances/EU List of Notified Chemical Substances
Canadian Domestic Substances List/Non-Domestic
Substances List
PICCS
Substances List
Philippines Inventory of Chemicals and Chemical Substances
ENCS
Japanese Existing and New Chemical Substances
IECSC
Chinese Inventory of Existing Chemical Substances
AICS
Australian Inventory of Chemical Substances
KECL
Korean Existing and Evaluated Chemical Substances
NZIoC
New Zealand Inventory of Chemicals
WEL
Workplace Exposure Limit
TWA
Time Weighted Average
ACGIH
American Conference of Governmental Industrial Hygienists
IARC
International Agency for Research on Cancer
DNEL
Derived No Effect Level
PNEC
Predicted No Effect Concentration
RPE
Respiratory Protective Equipment
LD50
Lethal Dose 50%
LC50
Lethal Concentration 50%
EC50
Effective Concentration 50%
NOEC
No Observed Effect Concentration
POW
Partition coefficient Octanol:Water
PBT
Persistent, Bioaccumulative, Toxic
vPvB
very Persistent, very Bioaccumulative
ICAO/IATA
International Civil Aviation Organization/International Air
Transport Association
IMO/IMDG
Transport Association
International Maritime Organization/International Maritime
Dangerous Goods Code
ADR
Dangerous Goods Code
European Agreement Concerning the International Carriage of
Dangerous Goods by Road
MARPOL
Dangerous Goods by Road
International Convention for the Prevention of Pollution from
Ships
OECD
Ships
Organisation for Economic Co-operation and Development
ATE
Acute Toxicity Estimate
BCF
Bioconcentration factor
VOC
(Volatile Organic Compound)
Key literature references and sources for data
https://echa.europa.eu/information-on-chemicals
Suppliers safety data sheet, Chemadvisor - LOLI, Merck index, RTECS
Suppliers safety data sheet, Chemadvisor - LOLI, Merck index, RTECS
Disclaimer
The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guidance for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered a warranty or quality specification. The information relates only to the specific material designated and may not be valid for such material used in combination with any other materials or in any process, unless specified in the text
Disclaimer:
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.