Chemical Safety Data Sheet MSDS / SDS
BENZOIC ACID-13C7
Revision Date:2026-03-21Revision Number:1
Product identifier
- Product name: BENZOIC ACID-13C7
- CBnumber: CB6320919
- CAS: 222412-89-7
- Synonyms: Benzoic acid-<sup>13</sup>C<sub>7</sub>
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 010-86108875
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P264 Wash skin thouroughly after handling.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
Hazard statements
H335 May cause respiratory irritation
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled
H318 Causes serious eye damage
H317 May cause an allergic skin reaction
H315 Causes skin irritation
H302 Harmful if swallowed
Substance
- Product name: BENZOIC ACID-13C7
- Synonyms: Benzoic acid-<sup>13</sup>C<sub>7</sub>
- CAS: 222412-89-7
- MF: C7H6O2
- MW: 129.18
4.1 Description of first-aid measures
General adviceShow this material safety data sheet to the doctor in attendance.
If inhaled
After inhalation: fresh air. Call in physician.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower.
In case of eye contact
After eye contact: rinse out with plenty of water. Immediately call in ophthalmologist.
Remove contact lenses.
If swallowed
Remove contact lenses.
After swallowing: immediately make victim drink water (two glasses at most). Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available
4.4 Notes to physician
No data available
5.1 Extinguishing media
Suitable extinguishing mediaWater Foam Carbon dioxide (CO2) Dry powder
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.
5.2 Special hazards arising from the substance or mixture
Carbon oxides
Combustible.
Vapors are heavier than air and may spread along floors.
Forms explosive mixtures with air on intense heating.
Development of hazardous combustion gases or vapours possible in the event of fire.
Combustible.
Vapors are heavier than air and may spread along floors.
Forms explosive mixtures with air on intense heating.
Development of hazardous combustion gases or vapours possible in the event of fire.
5.3 Advice for firefighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
Prevent fire extinguishing water from contaminating surface water or the ground water system.
Prevent fire extinguishing water from contaminating surface water or the ground water system.
6.1 Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Avoid generation and inhalation of dusts in all circumstances. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert.
For personal protection see section 8.
For personal protection see section 8.
6.2 Environmental precautions
Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up dry. Dispose of properly. Clean up affected area. Avoid generation of dusts.
6.4 Reference to other sections
For disposal see section 13.
7.1 Precautions for safe handling
Advice on safe handlingWork under hood. Do not inhale substance/mixture.
Hygiene measures
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
For precautions see section 2.2.
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Storage conditionsTightly closed. Dry. Keep in a well-ventilated place. Keep locked up or in an area accessible only to qualified or authorized persons.
Storage class
Storage class (TRGS 510): 6.1C: Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
8.1 Control parameters
Ingredients with workplace control parameters| ['Component', 'CAS-No.', 'Value', 'Control\nparameters', 'Basis'] |
|---|
| ['', 'Remarks', 'Not suspected as a human carcinogen\nDanger of cutaneous absorption'] |
Benzoic acid-13C7 222412- TWA 0.5 mg/m3 USA. ACGIH Threshold Limit 89-7 Values (TLV)
8.2 Exposure controls
Appropriate engineering controlsImmediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
Personal protective equipment
Eye/face protection
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Tightly fitting safety goggles
Skin protection
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN 16523-1 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell,
Internet: www.kcl.de).
Full contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:KCL 741 L
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN 16523-1 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell,
Internet: www.kcl.de).
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:KCL 741 L
Internet: www.kcl.de).
Full contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:KCL 741 L
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN 16523-1 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell,
Internet: www.kcl.de).
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:KCL 741 L
Body Protection
protective clothing
Respiratory protection
required when dusts are generated.
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Control of environmental exposure
Do not let product enter drains.
Information on basic physicochemical properties
- a) Physical stateFine crystals and fragments
- b) Colorwhite
- c) OdorNo data available
- d) Melting point/freezing pointMelting point/range: 121 - 125 °C - lit.
- e) Initial boiling point and boiling range249 °C - lit.
- f) Flammability (solid, gas)No data available
- g) Upper/lower flammability or explosive limitsNo data available
- h) Flash point121 °C - closed cup
- i) Autoignition temperatureNo data available
- j) Decomposition temperatureNo data available
- k) pHNo data available
- l) ViscosityViscosity, kinematic: No data available
Viscosity, dynamic: No data available - m) Water solubilityNo data available
- n) Partition coefficient n-octanol/waterNo data available
- o) Vapor pressureNo data available
- p) DensityNo data available
- Relative densityNo data available
- q) Relative vapor densityNo data available
- r) Particle characteristicsNo data available
- s) Explosive propertiesNo data available
- t) Oxidizing propertiesnone
9.2 Other safety information
No data available
10.1 Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
Stable
Stable
10.2 Possibility of hazardous reactions
Risk of ignition or formation of inflammable gases or vapours with:
Fluorine
Exothermic reaction with: bases
Strong oxidizing agents
Strong bases nitrites strong reducing agents
Fluorine
Exothermic reaction with: bases
Strong oxidizing agents
Strong bases nitrites strong reducing agents
10.3 Conditions to avoid
Strong heating.
10.4 Incompatible materials
No data available
10.5 Hazardous decomposition products
In the event of fire: see section 5
11.1 Information on toxicological effects
Acute toxicityLD50 Oral - Mouse - male and female - 2,250 mg/kg (OECD Test Guideline 401)
Remarks: The value is given in analogy to the following substances: Benzoic acid
Symptoms: Nausea, Vomiting, Irritation of mucous membranes
LC50 Inhalation - Rat - male and female - 4 h - > 12.2 mg/l - dust/mist
Remarks: (ECHA)
The value is given in analogy to the following substances: Benzoic acid
Symptoms: Cough, Possible damages:, mucosal irritations
LD50 Dermal - Rabbit - male and female - > 2,000 mg/kg
Remarks: (ECHA)
The value is given in analogy to the following substances: Benzoic acid
Skin corrosion/irritation
Remarks: The value is given in analogy to the following substances: Benzoic acid
Symptoms: Nausea, Vomiting, Irritation of mucous membranes
LC50 Inhalation - Rat - male and female - 4 h - > 12.2 mg/l - dust/mist
Remarks: (ECHA)
The value is given in analogy to the following substances: Benzoic acid
Symptoms: Cough, Possible damages:, mucosal irritations
LD50 Dermal - Rabbit - male and female - > 2,000 mg/kg
Remarks: (ECHA)
The value is given in analogy to the following substances: Benzoic acid
Skin - Guinea pig
Result: Skin irritation - 3 h
Remarks: (ECHA)
The value is given in analogy to the following substances: Benzoic acid
Remarks: (Regulation (EC) No 1272/2008, Annex VI)
Serious eye damage/eye irritation
Result: Skin irritation - 3 h
Remarks: (ECHA)
The value is given in analogy to the following substances: Benzoic acid
Remarks: (Regulation (EC) No 1272/2008, Annex VI)
Eyes - Rabbit
Result: Corrosive - 21 Days (Directive 67/548/EEC, Annex V, B.5.)
Remarks: The value is given in analogy to the following substances: Benzoic acid
Remarks: (Regulation (EC) No 1272/2008, Annex VI)
Respiratory or skin sensitization
Result: Corrosive - 21 Days (Directive 67/548/EEC, Annex V, B.5.)
Remarks: The value is given in analogy to the following substances: Benzoic acid
Remarks: (Regulation (EC) No 1272/2008, Annex VI)
Local lymph node assay (LLNA) - Mouse
Result: negative
Remarks: (ECHA)
The value is given in analogy to the following substances: Benzoic acid
Germ cell mutagenicity
Result: negative
Remarks: (ECHA)
The value is given in analogy to the following substances: Benzoic acid
Test Type: Mutagenicity (mammal cell test): chromosome aberration.
Test system: Chinese hamster fibroblasts
Metabolic activation: without metabolic activation
Result: Positive results were obtained in some in vitro tests.
Remarks: (ECHA)
The value is given in analogy to the following substances: Benzoic acidTest Type:
Micronucleus test
Test system: mouse lymphoma cells
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 487
Result: negative
Remarks: The value is given in analogy to the following substances: Benzoic acidCarcinogenicity
No data available
Reproductive toxicity
Test system: Chinese hamster fibroblasts
Metabolic activation: without metabolic activation
Result: Positive results were obtained in some in vitro tests.
Remarks: (ECHA)
The value is given in analogy to the following substances: Benzoic acidTest Type:
Micronucleus test
Test system: mouse lymphoma cells
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 487
Result: negative
Remarks: The value is given in analogy to the following substances: Benzoic acidCarcinogenicity
No data available
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Classified based on available data. For more details, see section 2
Specific target organ toxicity - repeated exposure
Inhalation - Causes damage to organs through prolonged or repeated exposure.
- Lungs
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
The value is given in analogy to the following substances: Benzoic acid
Aspiration hazard
- Lungs
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
The value is given in analogy to the following substances: Benzoic acid
Classified based on available data. For more details, see section 2
11.2 Additional Information
Repeated dose toxicity - Rat - male and female - inhalation (dust/mist/fume) - 28 Days
Remarks: The value is given in analogy to the following substances: Benzoic acid
Repeated dose toxicity - Rabbit - male and female - Dermal - 21 Days - NOAEL (No observed adverse effect level) - > 2,500 mg/kg
Remarks: The value is given in analogy to the following substances: Benzoic acid
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
Remarks: The value is given in analogy to the following substances: Benzoic acid
Repeated dose toxicity - Rabbit - male and female - Dermal - 21 Days - NOAEL (No observed adverse effect level) - > 2,500 mg/kg
Remarks: The value is given in analogy to the following substances: Benzoic acid
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
12.1 Toxicity
Toxicity to fish static test LC50 - Lepomis macrochirus - 44.6 mg/l - 96 h (US-EPA)
Remarks: The value is given in analogy to the following substances:
Benzoic acid
Toxicity to daphnia static test LC50 - Daphnia magna (Water flea) - > 100 mg/l - 48 h and other aquatic (US-EPA) invertebrates Remarks: The value is given in analogy to the following substances:
Benzoic acid
Toxicity to algae static test ErC50 - Pseudokirchneriella subcapitata - > 33.1 mg/l - 72 h (OECD Test Guideline 201)
Remarks: The value is given in analogy to the following substances:
Benzoic acid
Toxicity to bacteria static test IC50 - activated sludge - > 1,000 mg/l - 3 h (OECD Test Guideline 209)
Remarks: The value is given in analogy to the following substances:
Benzoic acid microtox test EC50 - Photobacterium phosphoreum - 17 mg/l - 30 min
Remarks: (Lit.)
The value is given in analogy to the following substances: Benzoic acid
Toxicity to semi-static test EC50 - Oncorhynchus mykiss (rainbow trout) - > 120 fish(Chronic toxicity) mg/l - 28 d (OECD Test Guideline 204)
Remarks: The value is given in analogy to the following substances:
Benzoic acid
Toxicity to daphnia semi-static test EC50 - Daphnia magna (Water flea) - > 25 mg/l - and other aquatic 21 d invertebrates(Chronic (OECD Test Guideline 211) toxicity) Remarks: The value is given in analogy to the following substances:
Benzoic acid
Remarks: The value is given in analogy to the following substances:
Benzoic acid
Toxicity to daphnia static test LC50 - Daphnia magna (Water flea) - > 100 mg/l - 48 h and other aquatic (US-EPA) invertebrates Remarks: The value is given in analogy to the following substances:
Benzoic acid
Toxicity to algae static test ErC50 - Pseudokirchneriella subcapitata - > 33.1 mg/l - 72 h (OECD Test Guideline 201)
Remarks: The value is given in analogy to the following substances:
Benzoic acid
Toxicity to bacteria static test IC50 - activated sludge - > 1,000 mg/l - 3 h (OECD Test Guideline 209)
Remarks: The value is given in analogy to the following substances:
Benzoic acid microtox test EC50 - Photobacterium phosphoreum - 17 mg/l - 30 min
Remarks: (Lit.)
The value is given in analogy to the following substances: Benzoic acid
Toxicity to semi-static test EC50 - Oncorhynchus mykiss (rainbow trout) - > 120 fish(Chronic toxicity) mg/l - 28 d (OECD Test Guideline 204)
Remarks: The value is given in analogy to the following substances:
Benzoic acid
Toxicity to daphnia semi-static test EC50 - Daphnia magna (Water flea) - > 25 mg/l - and other aquatic 21 d invertebrates(Chronic (OECD Test Guideline 211) toxicity) Remarks: The value is given in analogy to the following substances:
Benzoic acid
12.2 Persistence and degradability
Biodegradability anaerobic - Exposure time 35 d
Result: 89.5 % - Biodegradable (OECD Test Guideline 311)
Remarks: The value is given in analogy to the following substances:
Benzoic acid
Result: 89.5 % - Biodegradable (OECD Test Guideline 311)
Remarks: The value is given in analogy to the following substances:
Benzoic acid
12.3 Bioaccumulative potential
No data available
12.4 Mobility in soil
No data available
12.5 Results of PBT and vPvB assessment
PBT/vPvB assessment not available as chemical safety assessment not required/not conducted
12.6 Endocrine disrupting properties
No data available
12.7 Other adverse effects
No data available
13.1 Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company.
Offer surplus and non-recyclable solutions to a licensed disposal company.
14.1 UN number
ADR/RID: -
IMDG: -
IATA-DGR: -
IMDG: -
IATA-DGR: -
14.2 UN proper shipping name
ADR/RID: Not dangerous goods
IMDG: Not dangerous goods
IATA-DGR: Not dangerous goods
IMDG: Not dangerous goods
IATA-DGR: Not dangerous goods
14.3 Transport hazard class(es)
ADR/RID: -
IMDG: -
IATA-DGR: -
IMDG: -
IATA-DGR: -
14.4 Packaging group
ADR/RID: -
IMDG: -
IATA-DGR: -
IMDG: -
IATA-DGR: -
14.5 Environmental hazards
ADR/RID: no
IMDG Marine pollutant: no
IATA-DGR: no
IMDG Marine pollutant: no
IATA-DGR: no
14.6 Special precautions for user
14.7 Incompatible materials
Further information: Not classified as dangerous in the meaning of transport regulations.
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
National regulatory information
Law on the Prevention and Control of Occupational Diseases
Other regulations
Please pay attention on the waste treatment should also comply with local regulations requirement.
Law on the Prevention and Control of Occupational Diseases
Other regulations
Please pay attention on the waste treatment should also comply with local regulations requirement.
Abbreviations and acronyms
CAS: Chemical Abstracts Service
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
Disclaimer:
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.