Chemical Safety Data Sheet MSDS / SDS
Bis(4-bromophenyl) ether
Revision Date:2026-03-21Revision Number:1
Product identifier
- Product name: Bis(4-bromophenyl) ether
- CBnumber: CB2306780
- CAS: 2050-47-7
- EINECS Number: 218-090-7
- Synonyms: DIBROMODIPHENYLETHER;4,4'-dibromodiphenyl ether
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 010-86108875
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
P501 Dispose of contents/container to..…
P331 Do NOT induce vomiting.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P273 Avoid release to the environment.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
Hazard statements
H410 Very toxic to aquatic life with long lasting effects
H336 May cause drowsiness or dizziness
H315 Causes skin irritation
H304 May be fatal if swallowed and enters airways
H225 Highly Flammable liquid and vapour
Substance
- Product name: Bis(4-bromophenyl) ether
- Synonyms: DIBROMODIPHENYLETHER;4,4'-dibromodiphenyl ether
- CAS: 2050-47-7
- EC number: 218-090-7
- MF: C12H8Br2O
- MW: 328
General advice
Show this material safety data sheet to the doctor in attendance.
If inhaled
After inhalation: fresh air. Call in physician.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower.
In case of eye contact
After eye contact: rinse out with plenty of water. Remove contact lenses.
If swallowed
After swallowing: caution if victim vomits. Risk of aspiration! Keep airways free. Pulmonary failure possible after aspiration of vomit. Call a physician immediately.
Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11
Protection of first-aiders
For personal protection see section 8.
Notes to physician
No data available
Suitable extinguishing media
Foam Carbon dioxide (CO2) Dry powder
Unsuitable extinguishing media
For this substance/mixture no limitations of extin- guishing agents are given.
Specific hazards during fire fighting
Combustible. Pay attention to flashback. Vapors are heavier than air and may spread along floors. Development of hazardous combustion gases or vapours possible in the event of fire. Forms explosive mixtures with air at ambient temperatures.
Hazardous combustion products
Carbon oxides
Specific extinguishing methods
Remove container from danger zone and cool with water. Prevent fire extinguishing water from contaminating surface water or the ground water system.
Special protective equipment for fire-fighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
NFPA 704
0
1
0
| HEALTH | 0 | Poses no health hazard, no precautions necessary and would offer no hazard beyond that of ordinary combustible materials | |
| FIRE | 1 | Materials that require considerable preheating, under all ambient temperature conditions, before ignition and combustion can occur. Includes some finely divided suspended solids that do not require heating before ignition can occur. Flash point at or above 93.3 °C (200 °F). (e.g. mineral oil, ammonia) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Keep away from heat and sources of ignition. Evacuate the danger area, observe emergency procedures, consult an expert. Advice for emergency responders: For personal protection see section 8.
Environmental precautions
Do not let product enter drains. Risk of explosion.
Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up carefully with liquid-absorbent material . Dispose of properly. Clean up affected area.
Handling
Advice on protection against fire and explosionKeep away from open flames, hot surfaces and sources of ignition. Take precautionary measures against static discharge.
Advice on safe handling
Work under hood. Do not inhale substance/mixture. Avoid generation of vapours/aerosols.
Avoidance of contact
Strong oxidizing agents
Storage
Further information on storage conditionsKeep container tightly closed in a dry and wellventilated place. Keep away from heat and sources of ignition.
Storage class
3, Flammable liquids
Recommended storage temperature
2 - 8 °C
control parameter
Hazard composition and occupational exposure limitsDoes not contain substances with occupational exposure limits.
Engineering measures
No data available
Personal protective equipment
Respiratory protectionrequired when vapours/aerosols are generated.
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Recommended Filter type
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Filter type ABEK
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.
Eye/face protection
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Safety glasses
Skin and body protection
Safety glasses
Flame retardant antistatic protective clothing.
Hand protection
Remarks
required
Hygiene measures
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
Information on basic physicochemical properties
- Physical stateCrystalline
- Molecular weight328.00 g/mol
- Oxidizing propertiesnone
- Explosive propertiesNot classified as explosive.
- Flow timeNo data available
- Viscosity, kinematicNo data available
- Viscosity, dynamicNo data available
- Decomposition temperatureNo data available
- Autoignition temperatureNo data available
- Partition coefficient: n-octanol/waterNo data available
- Water solubilityinsoluble
- Density0.690 g/cm3
- Relative density1.6728 (rough estimate)
- Relative vapor densityNo data available
- Vapor pressure55 hPa (21 °C)
- Lower explosion limit / Lower flammability limitLower flammability limit
- Upper explosion limit / Upper flammability limitUpper flammability limit
- Self-ignition396 °C
- Burning rateNo data available
- Flammability (liquids)No data available
- Flammability (solid, gas)No data available
- Evaporation rateNo data available
- Flash point-12 °C
- Boiling point/boiling range98 - 99 °C (1,013 hPa)
- Melting point/ range-107 °C
- pHNo data available
- Odor ThresholdNo data available
- OdorNo data available
- Colorcolorless
- Appearanceclear, liquid
- SolubilityMethanol (Slightly)
Reactivity
Vapors may form explosive mixture with air.
Chemical stability
The product is chemically stable under standard ambi- ent conditions (room temperature) .
Possibility of hazardous reactions
No data available
Conditions to avoid
Warming.
Incompatible materials
Strong oxidizing agents
Hazardous decomposition products
In the event of fire: see section 5
11.1 Information on toxicological effects
Mixture Acute toxicityOral: No data available
Inhalation: No data available
Dermal: No data available
Skin corrosion/irritation
Inhalation: No data available
Dermal: No data available
Remarks: Mixture causes skin irritation.
Serious eye damage/eye irritation
Classified based on available data. For more details, see section 2
Respiratory or skin sensitization
Classified based on available data. For more details, see section 2
Germ cell mutagenicity
Classified based on available data. For more details, see section 2
Carcinogenicity
Classified based on available data. For more details, see section 2
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Mixture may cause drowsiness or dizziness.
Specific target organ toxicity - repeated exposure
Classified based on available data. For more details, see section 2
Aspiration hazard
Aspiration hazard, Aspiration may cause pulmonary edema and pneumonitis.
11.2 Additional Information
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
Other dangerous properties can not be excluded.
Handle in accordance with good industrial hygiene and safety practice.
Components isooctane
Other dangerous properties can not be excluded.
Handle in accordance with good industrial hygiene and safety practice.
Acute toxicity
LD50 Oral - Rat - male and female - > 5,000 mg/kg (OECD Test Guideline 401)
LC50 Inhalation - Rat - male and female - 4 h - > 33.52 mg/l - vapor (OECD Test Guideline 403)
Symptoms: mucosal irritations
LD50 Dermal - Rabbit - male and female - > 2,000 mg/kg (OECD Test Guideline 402)
LC50 Inhalation - Rat - male and female - 4 h - > 33.52 mg/l - vapor (OECD Test Guideline 403)
Symptoms: mucosal irritations
LD50 Dermal - Rabbit - male and female - > 2,000 mg/kg (OECD Test Guideline 402)
Skin corrosion/irritation
Skin - Rabbit
Result: Irritating to skin. - 24 h (OECD Test Guideline 404)
Remarks: Repeated or prolonged exposure may cause skin irritation and dermatitis, due to degreasing properties of the product.
Result: Irritating to skin. - 24 h (OECD Test Guideline 404)
Remarks: Repeated or prolonged exposure may cause skin irritation and dermatitis, due to degreasing properties of the product.
Serious eye damage/eye irritation
Eyes - Rabbit
Result: No eye irritation (OECD Test Guideline 405)
Result: No eye irritation (OECD Test Guideline 405)
Respiratory or skin sensitization
Maximization Test - Guinea pig
Result: negative (OECD Test Guideline 406)
Result: negative (OECD Test Guideline 406)
Germ cell mutagenicity
Test Type: Ames test
Test system: TA98
Result: negative
Test Type: In vitro mammalian cell gene mutation test
Test system: human lymphoblastoid cells
Result: negative
Method: OECD Test Guideline 486
Species: Rat - male - Liver cells
Result: negative
Test system: TA98
Result: negative
Test Type: In vitro mammalian cell gene mutation test
Test system: human lymphoblastoid cells
Result: negative
Method: OECD Test Guideline 486
Species: Rat - male - Liver cells
Result: negative
Carcinogenicity
Classified based on available data. For more details, see section 2
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
May cause drowsiness or dizziness. - Central nervous system
Acute inhalation toxicity - mucosal irritations
Acute inhalation toxicity - mucosal irritations
Specific target organ toxicity - repeated exposure
Classified based on available data. For more details, see section 2
Aspiration hazard
Aspiration hazard, Aspiration may cause pulmonary edema and pneumonit- is.
Ecotoxicity
Components:
isooctane:
Toxicity to fishLC50 (Oncorhynchus mykiss (rainbow trout)): 0.11 mg/l End point: mortality Exposure time: 96 h Test Type: semi-static test Analytical monitoring: yes Method: OECD Test Guideline 203 GLP: yes
Toxicity to daphnia and other aquatic invertebrates
EC50 (Daphnia magna (Water flea)): 0.4 mg/l End point: Immobilization Exposure time: 48 h Test Type: static test Analytical monitoring: yes Remarks: (in analogy to similar products) (ECHA) The value is given in analogy to the following substances: 2,3,4-Trimethylpentane
M-Factor (Acute aquatic toxicity)
1
Toxicity to daphnia and other aquatic invertebrates (Chronic toxicity)
EC50 (Daphnia magna (Water flea)): 0.23 mg/l Exposure time: 21 d Test Type: static test Analytical monitoring: yes Method: OECD Test Guideline 211 GLP: yes
M-Factor (Chronic aquatic toxicity)
1
Toxicity to microorganisms
EC0 (Pseudomonas putida): 10,000 mg/l Remarks: (IUCLID)
Persistence and degradability
Components:
isooctane:
Biodegradabilityaerobic Inoculum: activated sludge Concentration: 49 mg/l Result: Inherently biodegradable. Biodegradation: 51.3 % Exposure time: 28 d Method: OECD Test Guideline 301F
Bioaccumulative potential
Components:
isooctane:
BioaccumulationBioconcentration factor (BCF): 231
Partition coefficient: noctanol/water
log Pow: 4.6 Remarks: Bioaccumulation is not expected.
Mobility in soil
No data available
Other adverse effects
Components:
isooctane:
Results of PBT and vPvB assessmentSubstance does not meet the criteria for PBT or vPvB according to Regulation (EC) No 1907/2006, Annex XIII.
Additional ecological information
Biological effects: Endangers drinking-water supplies if allowed to enter soil and/or waters in large quantities. Discharge into the environment must be avoided.
Disposal methods
Waste from residuesOffer surplus and non-recyclable solutions to a licensed disposal company.
International Regulations
IATA-DGR
UN/ID No. : UN 1262
Proper shipping name : Octanes solution
Class : 3
Packing group : II
Labels : Class 3 - Flammable liquids
Packing instruction (cargo aircraft) : 364
Packing instruction (passenger aircraft) : 353
Proper shipping name : Octanes solution
Class : 3
Packing group : II
Labels : Class 3 - Flammable liquids
Packing instruction (cargo aircraft) : 364
Packing instruction (passenger aircraft) : 353
IMDG-Code
UN number : UN 1262
Proper shipping name : OCTANES SOLUTION
Class : 3
Packing group : II
Labels : 3
EmS Code : F-E, S-E
Marine pollutant : yes
Proper shipping name : OCTANES SOLUTION
Class : 3
Packing group : II
Labels : 3
EmS Code : F-E, S-E
Marine pollutant : yes
Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code
Not applicable for product as supplied.
Domestic regulation
Poison Inhalation Hazard : No GB 6944/12268
UN number : UN 1262
Proper shipping name : OCTANES
Class : 3
Packing group : II
Labels : 3
Domestic regulation
Poison Inhalation Hazard : No GB 6944/12268
UN number : UN 1262
Proper shipping name : OCTANES
Class : 3
Packing group : II
Labels : 3
Special precautions for user
The transport classification(s) provided herein are for informational purposes only, and solely based upon the properties of the unpackaged material as it is described within this Safety Data Sheet. Transportation classifications may vary by mode of transportation, package sizes, and variations in regional or country regulations.
National regulatory information
Law on the Prevention and Control of Occupational Diseases
Regulations on Safety Management of Hazardous Chemicals
Catalogue of Hazardous Chemicals Identification of Major Hazard Installations for Hazardous Chemicals (GB 18218)
Listed
No. / Code Chemical name / Category Threshold quantity
W5.3 Flammable liquids 1,000 t
Hazardous Chemicals for Priority Management
Listed under SAWS
Regulations on Occupational Labor Protection in the at workplaces where
Toxic Substances Are Used
Catalogue of Highly Toxic Chemicals
Not listed
Regulation of Environmental Management on the First Import of Chemicals and the Import and Export of Toxic Chemicals
China Severely Restricted Toxic Chemicals for Import and Export
Not listed
Regulation on the Administration of Precursor Chemicals
Catalogue and Classification of Precursor Chemicals
Not listed
Full text of other abbreviations
ACGIHUSA. ACGIH Threshold Limit Values (TLV)
ACGIH / TWA AIIC - Australian Invent Transport by Land of Bra bw - Body weight; CMR Standard of the German List (Canada); ECx - Conc associated with x% respo Chemical Substances (Jap response; ERG - Emerge GLP - Good Laboratory P cer; IATA - International Construction and Equipm Half maximal inhibitory c tion; IECSC - Inventory o tional Maritime Dangerou Industrial Safety and H Standardization; KECI - K tration to 50 % of a test (Median Lethal Dose); MA lution from Ships; n.o.s. No Observed (Adverse) E fect Level; NOELR - No Norm; NTP - National Toxi icals; OECD - Organizatio fice of Chemical Safety a and Toxic substance; PIC stances; (Q)SAR - (Quant (EC) No 1907/2006 of th Registration, Evaluation, Accelerating Decompositi Chemical Substance Inve Thailand Existing Chemica States); UN - United Nat Transport of Dangerous WHMIS - Workplace Hazar
8-hour, time-weighted average ry of Industrial Chemicals
ANTT - National Agency for il
ASTM - American Society for the Testing of Materials
- Carcinogen, Mutagen or Reproductive Toxicant
DIN nstitute for Standardisation
DSL - Domestic Substances ntration associated with x% response
ELx - Loading rate se
EmS - Emergency Schedule
ENCS - Existing and New n)
ErCx - Concentration associated with x% growth rate cy Response Guide
GHS - Globally Harmonized System
actice
IARC - International Agency for Research on Canir Transport Association
IBC - International Code for the nt of Ships carrying Dangerous Chemicals in Bulk
IC50 ncentration
ICAO - International Civil Aviation Organiza- Existing Chemical Substances in China
IMDG - Interna- Goods
IMO - International Maritime Organization
ISHL alth Law (Japan)
ISO - International Organisation for rea Existing Chemicals Inventory
LC50 - Lethal Concenopulation
LD50 - Lethal Dose to 50% of a test population POL - International Convention for the Prevention of Pol- Not Otherwise Specified
Nch - Chilean Norm
NO(A)EC fect Concentration
NO(A)EL - No Observed (Adverse) Efbservable Effect Loading Rate
NOM - Official Mexican ology Program
NZIoC - New Zealand Inventory of Chemfor Economic Co-operation and Development
OPPTS - Ofd Pollution Prevention
PBT - Persistent, Bioaccumulative S - Philippines Inventory of Chemicals and Chemical Subtative) Structure Activity Relationship
REACH - Regulation European Parliament and of the Council concerning the uthorisation and Restriction of Chemicals
SADT - Selfn Temperature
SDS - Safety Data Sheet
TCSI - Taiwan tory
TDG - Transportation of Dangerous Goods
TECI s Inventory
TSCA - Toxic Substances Control Act (United ons
UNRTDG - United Nations Recommendations on the oods
vPvB - Very Persistent and Very Bioaccumulative
ous Materials Information System
ANTT - National Agency for il
ASTM - American Society for the Testing of Materials
- Carcinogen, Mutagen or Reproductive Toxicant
DIN nstitute for Standardisation
DSL - Domestic Substances ntration associated with x% response
ELx - Loading rate se
EmS - Emergency Schedule
ENCS - Existing and New n)
ErCx - Concentration associated with x% growth rate cy Response Guide
GHS - Globally Harmonized System
actice
IARC - International Agency for Research on Canir Transport Association
IBC - International Code for the nt of Ships carrying Dangerous Chemicals in Bulk
IC50 ncentration
ICAO - International Civil Aviation Organiza- Existing Chemical Substances in China
IMDG - Interna- Goods
IMO - International Maritime Organization
ISHL alth Law (Japan)
ISO - International Organisation for rea Existing Chemicals Inventory
LC50 - Lethal Concenopulation
LD50 - Lethal Dose to 50% of a test population POL - International Convention for the Prevention of Pol- Not Otherwise Specified
Nch - Chilean Norm
NO(A)EC fect Concentration
NO(A)EL - No Observed (Adverse) Efbservable Effect Loading Rate
NOM - Official Mexican ology Program
NZIoC - New Zealand Inventory of Chemfor Economic Co-operation and Development
OPPTS - Ofd Pollution Prevention
PBT - Persistent, Bioaccumulative S - Philippines Inventory of Chemicals and Chemical Subtative) Structure Activity Relationship
REACH - Regulation European Parliament and of the Council concerning the uthorisation and Restriction of Chemicals
SADT - Selfn Temperature
SDS - Safety Data Sheet
TCSI - Taiwan tory
TDG - Transportation of Dangerous Goods
TECI s Inventory
TSCA - Toxic Substances Control Act (United ons
UNRTDG - United Nations Recommendations on the oods
vPvB - Very Persistent and Very Bioaccumulative
ous Materials Information System
Disclaimer:
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.