Chemical Safety Data Sheet MSDS / SDS
Chloromethane
Revision Date:2026-04-04Revision Number:1
Product identifier
- Product name: Chloromethane
- CBnumber: CB9673584
- CAS: 74-87-3
- EINECS Number: 200-817-4
- Synonyms: Methyl Chloride,CH3CL
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 010-86108875
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
P502 Refer to manufacturer/supplier for information on recovery/recycling
P410+P403 Protect from sunlight. Store in a well-ventilated place.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P202 Do not handle until all safety precautions have been read and understood.
Hazard statements
H420 Harms public health and the environment by destroying ozone in the upper atmosphere
H373 May cause damage to organs through prolonged or repeated exposure
H351 Suspected of causing cancer
H280 Contains gas under pressure; may explode if heated
H221 Flammable gas
Substance
- Product name: Chloromethane
- Synonyms: Methyl Chloride,CH3CL
- CAS: 74-87-3
- EC number: 200-817-4
- MF: CH3Cl
- MW: 50.49
If inhaled
Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER or doctor/ physician.
In case of skin contact
Take off all contaminated clothing immediately. If on skin, rinse well with water. Call a POISON CENTER or doctor/ physician.
In case of eye contact
Rinse with plenty of water. If easy to do, remove contact lens, if worn. Call a POISON CENTER or doctor/ physician.
If swallowed
Call a POISON CENTER or doctor/ physician. Rinse mouth.
Most important symptoms and effects, both acute and delayed
None known.
Suitable extinguishing media
Dry powder, Foam, Water spray, Carbon dioxide (CO2)
Specific hazards during fire fighting
No information available.
Specific extinguishing methods
Use extinguishing measures that are appropriate to local circumstances and the surrounding environment. Immediately evacuate personnel to safe areas. Remove undamaged containers from fire area if it is safe to do so.
Special protective equipment for fire-fighters
Use personal protective equipment.
NFPA 704
2
4
0
| HEALTH | 2 | Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury (e.g. diethyl ether, ammonium phosphate, iodine) | |
| FIRE | 4 | Will rapidly or completely vaporize at normal atmospheric pressure and temperature, or is readily dispersed in air and will burn readily. Includes pyrophoric substances. Flash point below room temperature at 22.8 °C (73 °F). (e.g. acetylene, propane, hydrogen gas) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Wear suitable protective equipment. Keep people away from and upwind of spill/leak. Ensure adequate ventilation. Entry to non-involved personnel should be controlled around the leakage area by roping off, etc.
Environmental precautions
Prevent product from entering drains.
Methods and materials for containment and cleaning up
Collect as much of the spill as possible with a suitable absorbent material.
Handling
Technical measuresPrevent generation of vapor or mist. Take precautionary measures against static discharge. Use explosion-proof equipment.
Local/Total ventilation
Ensure adequate ventilation. Handle product only in closed system or provide appropriate exhaust ventilation at machinery. Use a local exhaust ventilation.
Advice on safe handling
Avoid contact with skin, eyes and clothing. Wear personal protective equipment. Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. Do not subject to grinding, shock or friction. Wash hands and face thoroughly after handling.
Avoidance of contact
Oxidizing agents
Storage
Conditions for safe storageKeep container tightly closed. Store in a refrigerator. Keep in a well-ventilated place. Use explosion-proof equipment. Keep under inert gas. Store locked up.
Ingredients with workplace control parameters
| Components | CAS RN | Value type (Form of ex- posure) | Control parameters / Permissible con- centration | Basis |
|---|---|---|---|---|
| Tetrahydrofuran | 109-99-9 | PC-TWA | 300 mg/m3 | CN OEL |
| TWA | 50 ppm | ACGIH | ||
| STEL | 100 ppm | ACGIH | ||
| Methyl Chloride | 74-87-3 | PC-TWA | 60 mg/m3 | CN OEL |
| Further information: Skin | ||||
| PC-STEL | 120 mg/m3 | CN OEL | ||
| Further information: Skin | ||||
| TWA | 50 ppm | ACGIH | ||
| STEL | 100 ppm | ACGIH | ||
Components CAS RN Value type Control parameters Basis (Form of ex- / Permissible conposure) centration
Tetrahydrofuran 109-99-9 PC-TWA 300 mg/m3 CN OEL
TWA 50 ppm ACGIH
STEL 100 ppm ACGIH
Methyl Chloride 74-87-3 PC-TWA 60 mg/m3 CN OEL
Skin
PC-STEL 120 mg/m3 CN OEL
Further information
PC-STEL 120 mg/m3 CN OEL
Skin
TWA 50 ppm ACGIH
STEL 100 ppm ACGIH
TWA 50 ppm ACGIH
STEL 100 ppm ACGIH
Engineering measures
Install a closed system or local exhaust.
Also install safety shower and eye bath.
Also install safety shower and eye bath.
Personal protective equipment
Respiratory protectionGas mask
Self-contained breathing apparatus
Eye/face protection
Self-contained breathing apparatus
Safety glasses
Safety goggles
Face-shield
Skin and body protection
Safety goggles
Face-shield
Impervious protective clothing
Hand protection
Impervious gloves *Use personal protective equipment(PPE) approved under appropriate government standards and follow local and national regulations.
Information on basic physicochemical properties
- Dielectric constant12.6（-20℃）
- Physical stateColorless gas
- Henry's Law ConstantIn seawater: 5.22 at 5 °C, 6.36 at 10 °C, 8.72 at 15 °C, 9.35 at 20 °C, 11.20 at 25 °C (Moore, 2000)
- Vapour density1.74 (vs air)
- Density and/or relative density0.915 g/mL at 25 °C(lit.)
- Molecular weight50.49 g/mol
- Viscosity, kinematicNo data available
- Viscosity, dynamicNo data available
- Decomposition temperatureNo data available
- Autoignition temperatureNo data available
- Partition coefficient: n-octanol/waterNo data available
- Solubility in other solventswater: soluble5.32g/L at 25°C
- Water solubility5.347g/L(24.9 ºC)
- Solubility(ies)water: soluble5.32g/L at 25°C
- Vapor pressure3796 mm Hg ( 20 °C)
- Lower explosion limit / Lower flammability limit19%
- Upper explosion limit / Upper flammability limit19%
- FlammabilityNo data available
- Evaporation rateNo data available
- Flash point<-30 °F
- Boiling point/boiling range−24.2 °C(lit.)
- Melting point/freezing pointNo data available
- pHNo data available
- Odor ThresholdNo data available
- Odorfaint sweet ethereal odor
- Colorcolorless
- Appearanceliquid
Reactivity
No data available
Chemical stability
Stable under normal conditions.
Possibility of hazardous reactions
None under normal processing.
Conditions to avoid
Electrical spark Open flame Electrostatic discharge Exposure to air.
Incompatible materials
Oxidizing agents
Hazardous decomposition products
Carbon monoxide, Carbon dioxide (CO2), Hydrogen chloride gas
Acute toxicity
Product
Acute oral toxicity
Assessment: The component/mixture is moderately toxic after single ingestion.
Acute inhalation toxicity
Acute toxicity estimate: > 40 mg/l Exposure time: 4 h Test atmosphere: vapor Method: Calculation method
Components
Tetrahydrofuran
Acute oral toxicity
LD50 (Rat): 1,650 mg/kg Assessment: The component/mixture is moderately toxic after single ingestion.
Acute inhalation toxicity
LC50 (Rat): 21000 ppm Exposure time: 3 h Test atmosphere: gas Assessment: The substance or mixture has no acute inhalation toxicity
Acute toxicity (other routes of administration)
LD50 (Rat): 2,900 mg/kg Application Route: Intraperitoneal injection
Methyl Chloride
Acute oral toxicity
Assessment: The component/mixture is moderately toxic after single ingestion.
Acute inhalation toxicity
Assessment: The component/mixture is moderately toxic after short term inhalation.
Skin corrosion/irritation
Product
Result
Skin irritation
Components
Tetrahydrofuran
Result
Skin irritation
Serious eye damage/eye irritation
Product
Result
Eye irritation
Components
Tetrahydrofuran
Result
Eye irritation
Respiratory or skin sensitization
Classified based on available data. For more details, see section 2.
Germ cell mutagenicity
Product
Germ cell mutagenicity - Assessment
Suspected of inducing heritable mutations in the germ cells of humans.
Components
Methyl Chloride
Germ cell mutagenicity - Assessment
Suspected of inducing heritable mutations in the germ cells of humans.
Carcinogenicity
Product
Carcinogenicity - Assessment
Suspected human carcinogens
Components
Tetrahydrofuran
Carcinogenicity - Assessment
Suspected human carcinogens
Methyl Chloride
Carcinogenicity - Assessment
Suspected human carcinogens
Reproductive toxicity
Product
Reproductive toxicity - Assessment
Presumed human reproductive toxicant
Components
Methyl Chloride
Reproductive toxicity - Assessment
Presumed human reproductive toxicant
STOT-single exposure
Product
Assessment
May cause respiratory irritation.
Target Organs
Liver, Nervous system, Cardio-vascular system, Kidney
Assessment
May cause damage to organs.
Components
Tetrahydrofuran
Assessment
May cause respiratory irritation.
Target Organs
Nervous system
Assessment
May cause damage to organs.
Methyl Chloride
Assessment
May cause drowsiness or dizziness.
Target Organs
Liver, Nervous system, Cardio-vascular system, Kidney
Assessment
Causes damage to organs.
STOT-repeated exposure
Product
Target Organs
Liver, Nervous system, Kidney
Assessment
Causes damage to organs through prolonged or repeated exposure.
Target Organs
Central nervous system
Assessment
May cause damage to organs through prolonged or repeated exposure.
Components
Tetrahydrofuran
Target Organs
Liver, Nervous system, Kidney
Assessment
Causes damage to organs through prolonged or repeated exposure.
Methyl Chloride
Target Organs
Liver, Kidney, Central nervous system
Assessment
Causes damage to organs through prolonged or repeated exposure.
Target Organs
Systemic toxicity
Assessment
May cause damage to organs through prolonged or repeated exposure.
Repeated dose toxicity
Classified based on available data. For more details, see section 2.
Aspiration toxicity
Classified based on available data. For more details, see section 2.
RTECS No.
LU5950000 (Tetrahydrofuran)
Ecotoxicity
Components:
Tetrahydrofuran:
Toxicity to fishLC50 (Pimephales promelas (fathead minnow)): 2,160 mg/l Exposure time: 96 h
Toxicity to daphnia and other aquatic invertebrates
EC50 (Daphnia magna (Water flea)): 5,930 mg/l Exposure time: 24 h
Persistence and degradability
Components:
Tetrahydrofuran:
BiodegradabilityBiochemical oxygen demand Result: Readily biodegradable. Biodegradation: 100 %
Bioaccumulative potential
Components:
Tetrahydrofuran:
octanol/water
Partition coefficient: noctanol/water
0.46
Mobility in soil
Components:
Tetrahydrofuran:
tal compartments
Distribution among environmental compartments
Koc: 18 - 23
Other adverse effects
No data available
Disposal methods
Waste from residuesDisposal in accordance with local and national regulations. Take precautions against ignition or explode. Entrust disposal to a licensed waste disposal company.
Contaminated packaging
Disposal in accordance with local and national regulations. Before disposal of used container, remove contents completely.
International Regulations
IATA-DGR
UN/ID No.UN 1993
Proper shipping name
Flammable liquid, n.o.s.
Class
3
Packing group
II
IMDG-Code
UN numberUN 1993
Proper shipping name
FLAMMABLE LIQUID, N.O.S.
Class
3
Packing group
II
EmS Code
F-E, S-E
Domestic regulation
GB 6944/12268
UN numberUN 1993
Proper shipping name
FLAMMABLE LIQUID, N.O.S.
Class
3
Packing group
II
Regulations on Safety Management of Hazardous Chemicals
Catalogue of Hazardous ChemicalsListed
The ingredients of this product are reported in the following inventories
TCSIOn the inventory, or in compliance with the inventory
TSCA
All substances listed as active on the TSCA inventory
AIIC
On the inventory, or in compliance with the inventory
DSL
All components of this product are on the Canadian DSL
ENCS
On the inventory, or in compliance with the inventory
ISHL
On the inventory, or in compliance with the inventory
KECI
On the inventory, or in compliance with the inventory
PICCS
On the inventory, or in compliance with the inventory
IECSC
On the inventory, or in compliance with the inventory
NZIoC
Not in compliance with the inventory
TECI
On the inventory, or in compliance with the inventory
Abbreviations and acronyms
CAS: Chemical Abstracts Service
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
Disclaimer:
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.