11.1 Information on toxicological effects
Mixture Acute toxicity
Oral: No data available
Symptoms: Irritations of mucous membranes in the mouth, pharynx, oesophagus and gastrointestinal tract.
Symptoms: Possible symptoms:, mucosal irritations
Dermal: No data available
Skin corrosion/irritation
Remarks: Mixture causes skin irritation.
Serious eye damage/eye irritation
Remarks: Mixture causes serious eye irritation.
Respiratory or skin sensitization
Mixture may produce an allergic reaction.
Germ cell mutagenicity
Classified based on available data. For more details, see section 2
Carcinogenicity
Classified based on available data. For more details, see section 2
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Classified based on available data. For more details, see section 2
Specific target organ toxicity - repeated exposure
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2
11.2 Additional Information
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
Components divinylbenzene
Acute toxicity
LD50 Oral - Rat - male and female - > 2,000 mg/kg
Remarks: (ECHA)
Symptoms: mucosal irritations, Cough, Shortness of breath, Possible dam- ages:, damage of respiratory tract
Inhalation: Irritating to respiratory system.
Dermal: No data available
Skin corrosion/irritation
Skin - Rabbit
Result: Irritating to skin. - 2 Weeks
Remarks: (ECHA)
Serious eye damage/eye irritation
Eyes - Rabbit
Result: Causes serious eye irritation. - 30 s
Remarks: (ECHA)
Respiratory or skin sensitization
Classified based on available data. For more details, see section 2
Germ cell mutagenicity
Test Type: Ames test
Test system: Escherichia coli/Salmonella typhimurium
Result: negative
Carcinogenicity
Classified based on available data. For more details, see section 2
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Acute inhalation toxicity - mucosal irritations, Cough, Shortness of breath,
Possible damages:, damage of respiratory tract
Specific target organ toxicity - repeated exposure Aspiration hazard
Classified based on available data. For more details, see section 2
diethylbenzene Acute toxicity
LD50 Oral - Rat - male and female - 2,050 mg/kg (US EPA Test Guideline OPP 81-1)
Inhalation: No data available
LD50 Dermal - Rabbit - male and female - > 5,000 mg/kg
Remarks: (ECHA)
Skin corrosion/irritation
Skin - Rabbit
Result: Irritating to skin. - 4 h (OECD Test Guideline 404)
Serious eye damage/eye irritation
Eyes - Rabbit
Result: No eye irritation
Remarks: (ECHA)
Respiratory or skin sensitization
Buehler Test - Guinea pig
Result: Does not cause skin sensitisation.
(OECD Test Guideline 406)
Germ cell mutagenicity
Test Type: Ames test
Test system: S. typhimurium
Result: negative
Test Type: Chromosome aberration test in vitro
Test system: Chinese hamster ovary cells
Result: negative
Test Type: gene mutation test
Test system: Chinese hamster ovary cells
Result: negative
Method: OECD Test Guideline 474
Species: Mouse - male and female - Bone marrow
Result: negative
Carcinogenicity
Classified based on available data. For more details, see section 2
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Classified based on available data. For more details, see section 2
Specific target organ toxicity - repeated exposure
Classified based on available data. For more details, see section 2
Aspiration hazard
The substance or mixture is known to cause human aspiration toxicity haz- ards or has to be regarded as if it causes a human aspiration toxicity haz- ard.
4-tert-butylpyrocatechol Acute toxicity
LD50 Oral - Rat - male and female - 815 mg/kg (OECD Test Guideline 401)
Inhalation: No data available
LD50 Dermal - Rat - male and female - 1,331 mg/kg (OECD Test Guideline 402)
Skin corrosion/irritation
Skin - Rabbit
Result: Causes burns. - 4 h (OECD Test Guideline 404)
Serious eye damage/eye irritation
Eyes - Rabbit
Result: Irreversible effects on the eye (OECD Test Guideline 405)
Respiratory or skin sensitization
Maximisation Test - Guinea pig
Result: positive (OECD Test Guideline 406)
Germ cell mutagenicity
Test Type: Ames test
Test system: Salmonella typhimurium
Result: negative
Method: OECD Test Guideline 474
Species: Rat - male and female - Bone marrow
Result: negative
Carcinogenicity
Classified based on available data. For more details, see section 2
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Classified based on available data. For more details, see section 2
Specific target organ toxicity - repeated exposure
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2