Chemical Safety Data Sheet MSDS / SDS
DMT-dG(ib) Phosphoramidite
Revision Date:2026-03-21Revision Number:1
Product identifier
- Product name: DMT-dG(ib) Phosphoramidite
- CBnumber: CB7238714
- CAS: 93183-15-4
- EINECS Number: 685-519-6
- Synonyms: DMT-dG(iBu)-CE Phosphoramidite
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 010-86108875
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordWarning
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
Hazard statements
H319 Causes serious eye irritation
Substance
- Product name: DMT-dG(ib) Phosphoramidite
- Synonyms: DMT-dG(iBu)-CE Phosphoramidite
- CAS: 93183-15-4
- EC number: 685-519-6
- MF: C44H54N7O8P
- MW: 839.92
4.1 Description of first-aid measures
If inhaledAfter inhalation: fresh air.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower.
In case of eye contact
After eye contact: rinse out with plenty of water. Remove contact lenses.
If swallowed
After swallowing: make victim drink water (two glasses at most). Consult doctor if feeling unwell.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available
5.1 Extinguishing media
Suitable extinguishing mediaWater Foam Carbon dioxide (CO2) Dry powder
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.
5.2 Special hazards arising from the substance or mixture
Carbon oxides
Nitrogen oxides (NOx)
Oxides of phosphorus
Combustible.
Development of hazardous combustion gases or vapours possible in the event of fire.
Nitrogen oxides (NOx)
Oxides of phosphorus
Combustible.
Development of hazardous combustion gases or vapours possible in the event of fire.
5.3 Advice for firefighters
In the event of fire, wear self-contained breathing apparatus.
5.4 Further information
Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.
6.1 Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Avoid inhalation of dusts. Evacuate the danger area, observe emergency procedures, consult an expert.
For personal protection see section 8.
For personal protection see section 8.
6.2 Environmental precautions
Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up dry. Dispose of properly. Clean up affected area. Avoid generation of dusts.
6.4 Reference to other sections
For disposal see section 13.
7.1 Precautions for safe handling
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Storage conditionsTightly closed. Dry.
Storage stabilityRecommended storage temperature
2 - 8 °C
Storage class
Storage class (TRGS 510): 13: Non Combustible Solids
7.3 Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
8.1 Control parameters
Ingredients with workplace control parameters8.2 Exposure controls
Personal protective equipmentEye/face protection
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.
The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it.
Full contact
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Material tested: (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Material tested: (KCL 740 / Aldrich Z677272, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail sales@kcl.de, test method: EN374
If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the EC approved gloves. This recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario.
Respiratory protection
The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it.
Full contact
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Material tested: (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Material tested: (KCL 740 / Aldrich Z677272, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail sales@kcl.de, test method: EN374
If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the EC approved gloves. This recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario.
required when dusts are generated.
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Recommended Filter type: Filter type P1
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer.
These measures have to be properly documented.
Control of environmental exposure
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Recommended Filter type: Filter type P1
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer.
These measures have to be properly documented.
Do not let product enter drains.
Information on basic physicochemical properties
- a) Physical statepowder
- b) Colorwhite
- c) OdorNo data available
- d) Melting point/freezing pointMelting point/ range: - OECD Test Guideline 102Decomposes before melting.
- e) Initial boiling point and boiling range- OECD Test Guideline 103Decomposes below the boiling point.
- f) Flammability (solid, gas)readily combustible solids
The product is not flammable. - Test N.1: Test method for - g) Upper/lower flammability or explosive limitsNo data available
- h) Flash pointNo data available
- i) Autoignition temperatureNo data available
- j) Decomposition temperatureca. 115 °C
- k) pHNo data available
- l) ViscosityViscosity, kinematic: No data available
Viscosity, dynamic: No data available - m) Water solubility0,1 g/l at 20 °C - OECD Test Guideline 105
- n) Partition coefficient n-octanol/waterlog Pow: 4,17 at 20 °C - (calculated) - Potential bioaccumulation
- o) Vapor pressure< 0,1 hPa at 25 °C - OECD Test Guideline 104
- p) Density1,22 g/cm3 at 20 °C - OECD Test Guideline 109
- Relative density1,22 at 20 °C - OECD Test Guideline 109
- r) Particle characteristicsNo data available
- s) Explosive propertiesNo data available
- t) Oxidizing propertiesnone
- Solubilitysoluble, clear
9.2 Other safety information
No data available
10.1 Reactivity
The following applies in general to flammable organic substances and mixtures: in correspondingly fine distribution, when whirled up a dust explosion potential may generally be assumed.
10.2 Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
10.3 Possibility of hazardous reactions
No data available
10.4 Conditions to avoid
no information available
10.5 Incompatible materials
Strong oxidizing agents
10.6 Hazardous decomposition products
In the event of fire: see section 5
11.1 Information on toxicological effects
Acute toxicityLD50 Oral - Rat - female - > 2.000 mg/kg (OECD Test Guideline 423)
Remarks: (in analogy to similar products)
The value is given in analogy to the following substances: DMT-dT amidite
Inhalation: No data available
Dermal: No data available
Skin corrosion/irritation
Remarks: (in analogy to similar products)
The value is given in analogy to the following substances: DMT-dT amidite
Inhalation: No data available
Dermal: No data available
Skin - reconstructed human epidermis (RhE)
Result: No irritation (OECD Test Guideline 439)
Remarks: (in analogy to similar products)
The value is given in analogy to the following substances: DMT-dT amidite
Serious eye damage/eye irritation
Result: No irritation (OECD Test Guideline 439)
Remarks: (in analogy to similar products)
The value is given in analogy to the following substances: DMT-dT amidite
Eyes - In vitro study
Result: No eye irritation (OECD Test Guideline 492)
Remarks: (in analogy to similar products)
The value is given in analogy to the following substances: DMT-dT amidite
Respiratory or skin sensitization
Result: No eye irritation (OECD Test Guideline 492)
Remarks: (in analogy to similar products)
The value is given in analogy to the following substances: DMT-dT amidite
Local lymph node assay (LLNA) - Mouse
Result: negative (OECD Test Guideline 429)
Remarks: (in analogy to similar products)
The value is given in analogy to the following substances: DMT-dT amidite
Germ cell mutagenicity
Result: negative (OECD Test Guideline 429)
Remarks: (in analogy to similar products)
The value is given in analogy to the following substances: DMT-dT amidite
Test Type: Ames test
Test system: Salmonella typhimurium
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 471
Result: negative
Remarks: (in analogy to similar products)
The value is given in analogy to the following substances: DMT-dT amiditeCarcinogenicity
No data available
Reproductive toxicity
Test system: Salmonella typhimurium
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 471
Result: negative
Remarks: (in analogy to similar products)
The value is given in analogy to the following substances: DMT-dT amiditeCarcinogenicity
No data available
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Classified based on available data. For more details, see section 2
Specific target organ toxicity - repeated exposure
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2
11.2 Additional Information
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
12.1 Toxicity
Toxicity to daphnia semi-static test LC50 - Daphnia magna (Water flea) - > 100 mg/l - and other aquatic 48 h invertebrates (OECD Test Guideline 202)
Remarks: (in analogy to similar products)
The value is given in analogy to the following substances: DMT-dT amidite
Toxicity to algae static test ErC50 - Pseudokirchneriella subcapitata - > 100 mg/l - 72 h (OECD Test Guideline 201)
Remarks: (in analogy to similar products)
The value is given in analogy to the following substances: DMT-dT amidite static test NOEC - Pseudokirchneriella subcapitata - > 100 mg/l - 72 h (OECD Test Guideline 201)
Remarks: (in analogy to similar products)
The value is given in analogy to the following substances: DMT-dT amidite
Remarks: (in analogy to similar products)
The value is given in analogy to the following substances: DMT-dT amidite
Toxicity to algae static test ErC50 - Pseudokirchneriella subcapitata - > 100 mg/l - 72 h (OECD Test Guideline 201)
Remarks: (in analogy to similar products)
The value is given in analogy to the following substances: DMT-dT amidite static test NOEC - Pseudokirchneriella subcapitata - > 100 mg/l - 72 h (OECD Test Guideline 201)
Remarks: (in analogy to similar products)
The value is given in analogy to the following substances: DMT-dT amidite
12.2 Persistence and degradability
Biodegradability aerobic - Exposure time 28 d
Result: 4 - 5 % - Not readily biodegradable.
(OECD Test Guideline 301F)
Remarks: (in analogy to similar products)
The value is given in analogy to the following substances: DMT-dT amidite
Result: 4 - 5 % - Not readily biodegradable.
(OECD Test Guideline 301F)
Remarks: (in analogy to similar products)
The value is given in analogy to the following substances: DMT-dT amidite
12.3 Bioaccumulative potential
No data available
12.4 Mobility in soil
No data available
12.5 Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
12.6 Endocrine disrupting properties
No data available
12.7 Other adverse effects
No data available
14.1 UN number
ADR/RID: -
IMDG: -
IATA: -
IMDG: -
IATA: -
14.2 UN proper shipping name
ADR/RID: Not dangerous goods
IMDG: Not dangerous goods
IATA: Not dangerous goods
IMDG: Not dangerous goods
IATA: Not dangerous goods
14.3 Transport hazard class(es)
ADR/RID: -
IMDG: -
IATA: -
IMDG: -
IATA: -
14.4 Packaging group
ADR/RID: -
IMDG: -
IATA: -
IMDG: -
IATA: -
14.5 Environmental hazards
ADR/RID: no
IMDG Marine pollutant: no
IATA: no
IMDG Marine pollutant: no
IATA: no
14.6 Special precautions for user
No data available
Further information: Not classified as dangerous in the meaning of transport regulations.
Further information: Not classified as dangerous in the meaning of transport regulations.
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
This material safety data sheet complies with the requirements of Regulation (EC) No.
1907/2006.
1907/2006.
15.2 Chemical Safety Assessment
For this product a chemical safety assessment was not carried out
Full text of other abbreviations
ADN - European Agreement concerning the International Carriage of Dangerous Goods by Inland Waterways
ADR - Agreement concerning the International Carriage ofDangerous Goods by Road
AIIC - Australian Inventory of Industrial Chemicals
ASTM -American Society for the Testing of Materials
bw - Body weight
CMR - Carcinogen,Mutagen or Reproductive Toxicant
DIN - Standard of the German Institute forStandardisation
DSL - Domestic Substances List (Canada)
ECx - Concentration associated with x% response
ELx - Loading rate associated with x% response
EmS -Emergency Schedule
ENCS - Existing and New Chemical Substances (Japan)
ErCx -Concentration associated with x% growth rate response
GHS - Globally HarmonizedSystem
GLP - Good Laboratory Practice
IARC - International Agency for Research onCancer
IATA - International Air Transport Association
IBC - International Code for theConstruction and Equipment of Ships carrying Dangerous Chemicals in Bulk
IC50 - Half maximal inhibitory concentration
ICAO - International Civil Aviation Organization
IECSC - Inventory of Existing Chemical Substances in China
IMDG - InternationalMaritime Dangerous Goods
IMO - International Maritime Organization
ISHL - IndustrialSafety and Health Law (Japan)
ISO - International Organisation for Standardization
KECI - Korea Existing Chemicals Inventory
LC50 - Lethal Concentration to 50 % of a test population
LD50 - Lethal Dose to 50% of a test population (Median Lethal Dose)
MARPOL - International Convention for the Prevention of Pollution from Ships
n.o.s. -Not Otherwise Specified
NO(A)EC - No Observed (Adverse) Effect Concentration
NO(A)EL - No Observed (Adverse) Effect Level
NOELR - No Observable Effect LoadingRate
NZIoC - New Zealand Inventory of Chemicals
OECD - Organization for EconomicCo-operation and Development
OPPTS - Office of Chemical Safety and PollutionPrevention
PBT - Persistent, Bioaccumulative and Toxic substance
PICCS - PhilippinesInventory of Chemicals and Chemical Substances
(Q)SAR - (Quantitative) StructureActivity Relationship
REACH - Regulation (EC) No 1907/2006 of the EuropeanParliament and of the Council concerning the Registration, Evaluation, Authorisation andRestriction of Chemicals
RID - Regulations concerning the International Carriage ofDangerous Goods by Rail
SADT - Self-Accelerating Decomposition Temperature
SDS -Safety Data Sheet
TCSI - Taiwan Chemical Substance Inventory
TECI - ThailandExisting Chemicals Inventory
TSCA - Toxic Substances Control Act (United States)
UN - United Nations
UNRTDG - United Nations Recommendations on the Transport ofDangerous Goods
vPvB - Very Persistent and Very Bioaccumulative
ADR - Agreement concerning the International Carriage ofDangerous Goods by Road
AIIC - Australian Inventory of Industrial Chemicals
ASTM -American Society for the Testing of Materials
bw - Body weight
CMR - Carcinogen,Mutagen or Reproductive Toxicant
DIN - Standard of the German Institute forStandardisation
DSL - Domestic Substances List (Canada)
ECx - Concentration associated with x% response
ELx - Loading rate associated with x% response
EmS -Emergency Schedule
ENCS - Existing and New Chemical Substances (Japan)
ErCx -Concentration associated with x% growth rate response
GHS - Globally HarmonizedSystem
GLP - Good Laboratory Practice
IARC - International Agency for Research onCancer
IATA - International Air Transport Association
IBC - International Code for theConstruction and Equipment of Ships carrying Dangerous Chemicals in Bulk
IC50 - Half maximal inhibitory concentration
ICAO - International Civil Aviation Organization
IECSC - Inventory of Existing Chemical Substances in China
IMDG - InternationalMaritime Dangerous Goods
IMO - International Maritime Organization
ISHL - IndustrialSafety and Health Law (Japan)
ISO - International Organisation for Standardization
KECI - Korea Existing Chemicals Inventory
LC50 - Lethal Concentration to 50 % of a test population
LD50 - Lethal Dose to 50% of a test population (Median Lethal Dose)
MARPOL - International Convention for the Prevention of Pollution from Ships
n.o.s. -Not Otherwise Specified
NO(A)EC - No Observed (Adverse) Effect Concentration
NO(A)EL - No Observed (Adverse) Effect Level
NOELR - No Observable Effect LoadingRate
NZIoC - New Zealand Inventory of Chemicals
OECD - Organization for EconomicCo-operation and Development
OPPTS - Office of Chemical Safety and PollutionPrevention
PBT - Persistent, Bioaccumulative and Toxic substance
PICCS - PhilippinesInventory of Chemicals and Chemical Substances
(Q)SAR - (Quantitative) StructureActivity Relationship
REACH - Regulation (EC) No 1907/2006 of the EuropeanParliament and of the Council concerning the Registration, Evaluation, Authorisation andRestriction of Chemicals
RID - Regulations concerning the International Carriage ofDangerous Goods by Rail
SADT - Self-Accelerating Decomposition Temperature
SDS -Safety Data Sheet
TCSI - Taiwan Chemical Substance Inventory
TECI - ThailandExisting Chemicals Inventory
TSCA - Toxic Substances Control Act (United States)
UN - United Nations
UNRTDG - United Nations Recommendations on the Transport ofDangerous Goods
vPvB - Very Persistent and Very Bioaccumulative
Disclaimer:
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.
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