Chemical Safety Data Sheet MSDS / SDS

Ethylamine

Revision Date:2026-03-21Revision Number:1

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier

  • Product name: Ethylamine
  • CBnumber: CB8205711
  • CAS: 75-04-7
  • EINECS Number: 200-834-7
  • Synonyms: EA;Ethylamine solution

Relevant identified uses of the substance or mixture and uses advised against

  • Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
  • Uses advised against: none

Company Identification

  • Company: Chemicalbook
  • Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
  • Telephone: 010-86108875

SECTION 2: Hazards identification

GHS Label elements, including precautionary statements

  • Symbol(GHS)
  • Signal wordDanger
Precautionary statements
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
Hazard statements
H225 Highly Flammable liquid and vapour
H302 Harmful if swallowed
H311 Toxic in contact with skin
H314 Causes severe skin burns and eye damage
H335 May cause respiratory irritation

SECTION 3: Composition/information on ingredients

Substance

  • Product name: Ethylamine
  • Synonyms: EA;Ethylamine solution
  • CAS: 75-04-7
  • EC number: 200-834-7
  • MF: C2H7N
  • MW: 45.08

SECTION 4: First aid measures

4.1 Description of first aid measures

General advice
First aiders need to protect themselves. Show this safety data sheet to the doctor in attendance.
If inhaled
After inhalation: fresh air. Call in physician.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. Call a physician immediately.
In case of eye contact
After eye contact: rinse out with plenty of water. Immediately call in ophthalmologist.
Remove contact lenses.
If swallowed
After swallowing: make victim drink water (two glasses at most), avoid vomiting (risk of perforation). Call a physician immediately. Do not attempt to neutralise.

4.2 Most important symptoms and effects, both acute and delayed

The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11

4.3 Indication of any immediate medical attention and special treatment needed

No data available

SECTION 5: Firefighting measures

5.1 Extinguishing media

Suitable extinguishing media
Water Foam Carbon dioxide (CO2) Dry powder
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.

5.2 Special hazards arising from the substance or mixture

Carbon oxides
Nitrogen oxides (NOx)
Carbon oxides
Combustible.
Pay attention to flashback.
Vapours are heavier than air and may spread along floors.
Development of hazardous combustion gases or vapours possible in the event of fire.
Forms explosive mixtures with air at ambient temperatures.

5.3 Advice for firefighters

Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.

5.4 Further information

Remove container from danger zone and cool with water. Suppress (knock down) gases/vapours/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.

NFPA 704

3
4
0
HEALTH 3 Short exposure could cause serious temporary or moderate residual injury (e.g. liquid hydrogen, sulfuric acid, calcium hypochlorite, hexafluorosilicic acid)
FIRE 4 Will rapidly or completely vaporize at normal atmospheric pressure and temperature, or is readily dispersed in air and will burn readily. Includes pyrophoric substances. Flash point below room temperature at 22.8 °C (73 °F). (e.g. acetylene, propane, hydrogen gas)
REACT 0 Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2)
SPEC. HAZ.

SECTION 6: Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Advice for non-emergency personnel: Do not breathe vapours, aerosols. Avoid substance contact. Ensure adequate ventilation. Keep away from heat and sources of ignition.
Evacuate the danger area, observe emergency procedures, consult an expert.
For personal protection see section 8.

6.2 Environmental precautions

Do not let product enter drains. Risk of explosion.

6.3 Methods and materials for containment and cleaning up

Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up carefully with liquid-absorbent material (e.g.
Chemizorb®). Dispose of properly. Clean up affected area.

6.4 Reference to other sections

For disposal see section 13.

SECTION 7: Handling and storage

7.1 Precautions for safe handling

Advice on safe handling
Work under hood. Do not inhale substance/mixture. Avoid generation of vapours/aerosols.
Advice on protection against fire and explosion
Keep away from open flames, hot surfaces and sources of ignition.Take precautionary measures against static discharge.
Hygiene measures
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
For precautions see section 2.2.

7.2 Conditions for safe storage, including any incompatibilities

Storage conditions
Keep container tightly closed in a dry and well-ventilated place. Keep away from heat and sources of ignition.
Test for peroxide formation periodically and before distillation. Dry residue is explosive.
Test for peroxide formation periodically and before distillation.
Storage class
Storage class (TRGS 510): 3: Flammable liquids

7.3 Specific end use(s)

Apart from the uses mentioned in section 1.2 no other specific uses are stipulated

SECTION 8: Exposure controls/personal protection

8.1 Control parameters

Ingredients with workplace control parameters

8.2 Exposure controls

Personal protective equipment
Eye/face protection
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Tightly fitting safety goggles
Skin protection
required
Body Protection
Flame retardant antistatic protective clothing.
Respiratory protection
required when vapours/aerosols are generated.
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Recommended Filter type: Filter type ABEK
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer.
These measures have to be properly documented.
Control of environmental exposure
Do not let product enter drains. Risk of explosion.

SECTION 9: Physical and chemical properties

Information on basic physicochemical properties

  • a) Physical stateliquid, clear
  • b) Colorcolourless
  • c) Odorether-like
  • d) Melting point/freezing pointNo data available
  • e) Initial boiling point and boiling range17 °C
  • f) Flammability (solid, gas)No data available
  • g) Upper/lower flammability or explosive limitsUpper explosion limit: 11,8 %(V)
    Lower explosion limit: 1,8 %(V)
  • h) Flash point-31 °C - closed cup
  • i) Autoignition temperature215 °C at 1.013 hPa
  • j) Decomposition temperatureNo data available
  • k) pHca.7
  • l) ViscosityViscosity, kinematic: 0,518 mm2/s at 25 °C 0,403 mm2/s at 50 °C
    Viscosity, dynamic: No data available
  • m) Water solubilitysoluble
  • n) Partition coefficient n-octanol/waterlog Pow: 0,45 at 25 °C - Bioaccumulation is not expected.
  • o) Vapor pressure332,231 hPa at 20 °C 1.181,42 hPa at 55 °C
  • p) Density0,856 g/cm3
  • Relative density0.81 g/mL at 20 °C
  • q) Relative vapour density1.56 (15 °C, vs air)
  • r) Particle characteristicsNo data available
  • s) Explosive propertiesmixture.
    Not explosive, In use may form flammable/explosive vapour-air
  • t) Oxidizing propertiesnone
  • Solubilitysoluble in water in all proportions; soluble in ethanol, methanol, paraffin hydrocarbons, aromatic and aliphatic hydrocarbons, ethyl ether, ethyl acetate, acetone, and mineral oil.
  • Henry's Law Constant1.23(x 10-5 atmm3/mol at 25 °C) (Christie and Crisp, 1967)
  • Dielectric constant6.9(10℃)

9.2 Other safety information

Surface tension
26,4 mN/m at 25 °C Relative vapour ca.2,5 at 25 °C - (Air = 1.0) density

SECTION 10: Stability and reactivity

10.1 Reactivity

Formation of peroxides possible.
Vapours may form explosive mixture with air.

10.2 Chemical stability

The product is chemically stable under standard ambient conditions (room temperature) .

10.3 Possibility of hazardous reactions

No data available

10.4 Conditions to avoid

Warming.
Moisture.

10.5 Incompatible materials

Zinc, Oxidizing agents, Strong oxidizing agents, Copper, Strong acids, Oxygen, Nickel,
Ethylamine, anhydrous is packaged in steel cylinders. Cool to 0°C before opening.
Incompatible with silver, mercury and brass.

10.6 Hazardous decomposition products

Peroxides
In the event of fire: see section 5

SECTION 11: Toxicological information

11.1 Information on toxicological effects

Mixture Acute toxicity
Oral: No data available
Acute toxicity estimate Oral - 1.832 mg/kg (Calculation method)
Symptoms: If ingested, severe burns of the mouth and throat, as well as a danger of perforation of the oesophagus and the stomach.
Acute toxicity estimate Inhalation - 4 h - > 20 mg/l - vapour(Calculation method)
Symptoms: mucosal irritations, Cough, Shortness of breath, Possible damages:, damage of respiratory tract
Dermal: No data available
Skin corrosion/irritation
Remarks: Mixture causes burns.
Serious eye damage/eye irritation
Remarks: Mixture causes serious eye damage.
Risk of blindness!
Respiratory or skin sensitization
Classified based on available data. For more details, see section 2
Germ cell mutagenicity
Classified based on available data. For more details, see section 2
Carcinogenicity
Evidence of a carcinogenic effect.
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Mixture may cause respiratory irritation.
Mixture may cause drowsiness or dizziness.
Specific target organ toxicity - repeated exposure
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2

11.2 Additional Information

Endocrine disrupting properties
Product:
Assessment : The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.
Central nervous system depression, narcosis, Cough, chest pain, Difficulty in breathing,
Nausea, Dizziness, Headache, Unconsciousness
Other dangerous properties can not be excluded.
This substance should be handled with particular care.
Handle in accordance with good industrial hygiene and safety practice.
Components Tetrahydrofuran
Acute toxicity
LD50 Oral - Rat - male and female - 1.650 mg/kg
Remarks: (ECHA)
Symptoms: Irritation of mucous membranes
Acute toxicity estimate Oral - 1.650 mg/kg (ATE value derived from LD50/LC50 value)
LC50 Inhalation - Rat - male and female - 6 h - > 14,7 mg/l - vapour (US-EPA)
LD50 Dermal - Rat - male and female - > 2.000 mg/kg (OECD Test Guideline 402)
Skin corrosion/irritation
Skin - Rabbit
Result: No skin irritation - 72 h (Draize Test)
Remarks: Repeated or prolonged exposure may cause skin irritation and dermatitis, due to degreasing properties of the product.
Serious eye damage/eye irritation
Eyes - Rabbit
Result: Causes serious eye irritation.
Remarks: (IUCLID)
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Respiratory or skin sensitization
Local lymph node assay (LLNA) - Mouse
Result: negative (OECD Test Guideline 429)
Germ cell mutagenicity
Test Type: Ames test
Test system: S. typhimurium
Result: negative
Test Type: In vitro mammalian cell gene mutation test
Test system: Chinese hamster ovary cells
Result: negative
Test Type: Chromosome aberration test in vitro
Test system: Chinese hamster ovary cells
Result: negative
Method: OECD Test Guideline 474
Species: Mouse - male and female - Red blood cells (erythrocytes)
Result: negative
Carcinogenicity
Suspected of causing cancer.
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Inhalation - May cause respiratory irritation. - Central nervous system
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
May cause drowsiness or dizziness.
Acute oral toxicity - Irritation of mucous membranes
Specific target organ toxicity - repeated exposure Aspiration hazard
Classified based on available data. For more details, see section 2
Ethylamine Acute toxicity
Oral: No data available
LC50 Inhalation - Rat - male and female - 4 h - 8,1 mg/l - gas (OECD Test Guideline 403)
Dermal: No data available
Skin corrosion/irritation
Classified based on available data. For more details, see section 2
Serious eye damage/eye irritation
Remarks: Causes serious eye irritation.
Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Respiratory or skin sensitization
Classified based on available data. For more details, see section 2
Germ cell mutagenicity
Test Type: Ames test
Test system: S. typhimurium
Result: negative
Remarks: (National Toxicology Program)
Carcinogenicity
Classified based on available data. For more details, see section 2
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
May cause respiratory irritation.
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Specific target organ toxicity - repeated exposure Aspiration hazard
Classified based on available data. For more details, see section 2

SECTION 12: Ecological information

12.1 Toxicity

Mixture
No data available

12.2 Persistence and degradability

No data available

12.3 Bioaccumulative potential

No data available

12.4 Mobility in soil

No data available

12.5 Results of PBT and vPvB assessment

This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

12.6 Endocrine disrupting properties

Product:
Assessment : The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission
Delegated regulation (EU) 2017/2100 or Commission
Regulation (EU) 2018/605 at levels of 0.1% or higher.

12.7 Other adverse effects

No data available
Components Tetrahydrofuran
Toxicity to fish flow-through test LC50 - Pimephales promelas (fathead minnow) - 2.160 mg/l - 96 h (OECD Test Guideline 203)
Toxicity to daphnia static test EC50 - Daphnia magna (Water flea) - 3.485 mg/l - and other aquatic 48 h invertebrates (OECD Test Guideline 202)
Toxicity to flow-through test NOEC - Pimephales promelas (fathead fish(Chronic toxicity) minnow) - 216 mg/l - 33 d
Remarks: (ECHA)
Ethylamine
Toxicity to fish static test LC50 - Leuciscus idus (Golden orfe) - > 500 mg/l - 96 h (DIN 38412 part 15)
Toxicity to daphnia semi-static test LC50 - Ceriodaphnia dubia (water flea) - 7,9 and other aquatic mg/l - 48 h invertebrates (US-EPA)
Toxicity to bacteria static test EC20 - activated sludge - 240 mg/l - 30 min (ISO 8192)
Toxicity to daphnia semi-static test NOEC - Ceriodaphnia dubia (water flea) - 3,2 and other aquatic mg/l - 7 d invertebrates(Chronic (US-EPA) toxicity)

SECTION 13: Disposal considerations

13.1 Waste treatment methods

No data available

SECTION 14: Transport information

14.1 UN number

ADR/RID: 2056
IMDG: 2056
IATA: 2056

14.2 UN proper shipping name

ADR/RID: TETRAHYDROFURAN, SOLUTION
IMDG: TETRAHYDROFURAN, SOLUTION
IATA: Tetrahydrofuran, SOLUTION

14.3 Transport hazard class(es)

ADR/RID: 3
IMDG: 3
IATA: 3

14.4 Packaging group

ADR/RID: II
IMDG: II
IATA: II

14.5 Environmental hazards

ADR/RID: no
IMDG Marine pollutant: no
IATA: no

14.6 Special precautions for user

Tunnel restriction code : (D/E)
Further information : No data available

14.7 Maritime transport in bulk according to IMO instruments

Not applicable for product as supplied.

SECTION 15: Regulatory information

15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture

This material safety data sheet complies with the requirements of Regulation (EC) No.
1907/2006.
Authorisations and/or restrictions on use National legislation
Seveso III: Directive 2012/18/EU of the P5c FLAMMABLE LIQUIDS
European Parliament and of the Council on the control of major-accident hazards involving dangerous substances.

15.2 Chemical safety assessment

For this product a chemical safety assessment was not carried out

SECTION 16: Other information

Full text of other abbreviations

ADN - European Agreement concerning the International Carriage of Dangerous Goods by Inland Waterways
ADR - Agreement concerning the International Carriage ofDangerous Goods by Road
AIIC - Australian Inventory of Industrial Chemicals
ASTM -American Society for the Testing of Materials
bw - Body weight
CMR - Carcinogen,Mutagen or Reproductive Toxicant
DIN - Standard of the German Institute forStandardisation
DSL - Domestic Substances List (Canada)
ECx - Concentration associated with x% response
ELx - Loading rate associated with x% response
EmS -Emergency Schedule
ENCS - Existing and New Chemical Substances (Japan)
ErCx -Concentration associated with x% growth rate response
GHS - Globally HarmonizedSystem
GLP - Good Laboratory Practice
IARC - International Agency for Research onCancer
IATA - International Air Transport Association
IBC - International Code for theConstruction and Equipment of Ships carrying Dangerous Chemicals in Bulk
IC50 - Half maximal inhibitory concentration
ICAO - International Civil Aviation Organization
IECSC - Inventory of Existing Chemical Substances in China
IMDG - InternationalMaritime Dangerous Goods
IMO - International Maritime Organization
ISHL - IndustrialSafety and Health Law (Japan)
ISO - International Organisation for Standardization
KECI - Korea Existing Chemicals Inventory
LC50 - Lethal Concentration to 50 % of a test population
LD50 - Lethal Dose to 50% of a test population (Median Lethal Dose)
MARPOL - International Convention for the Prevention of Pollution from Ships
n.o.s. -Not Otherwise Specified
NO(A)EC - No Observed (Adverse) Effect Concentration
NO(A)EL - No Observed (Adverse) Effect Level
NOELR - No Observable Effect LoadingRate
NZIoC - New Zealand Inventory of Chemicals
OECD - Organization for EconomicCo-operation and Development
OPPTS - Office of Chemical Safety and PollutionPrevention
PBT - Persistent, Bioaccumulative and Toxic substance
PICCS - PhilippinesInventory of Chemicals and Chemical Substances
(Q)SAR - (Quantitative) StructureActivity Relationship
REACH - Regulation (EC) No 1907/2006 of the EuropeanParliament and of the Council concerning the Registration, Evaluation, Authorisation andRestriction of Chemicals
RID - Regulations concerning the International Carriage ofDangerous Goods by Rail
SADT - Self-Accelerating Decomposition Temperature
SDS -Safety Data Sheet
TCSI - Taiwan Chemical Substance Inventory
TECI - ThailandExisting Chemicals Inventory
TSCA - Toxic Substances Control Act (United States)
UN - United Nations
UNRTDG - United Nations Recommendations on the Transport ofDangerous Goods
vPvB - Very Persistent and Very Bioaccumulative
Disclaimer:

The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.

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