Chemical Safety Data Sheet MSDS / SDS

Homosalate

Revision Date:2026-03-21Revision Number:1

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier

  • Product name: Homosalate
  • CBnumber: CB2203124
  • CAS: 118-56-9
  • EINECS Number: 204-260-8
  • Synonyms: HMS;HOMO METHYL SALICYLATE

Relevant identified uses of the substance or mixture and uses advised against

  • Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
  • Uses advised against: none

Company Identification

  • Company: Chemicalbook
  • Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
  • Telephone: 010-86108875

SECTION 2: Hazards identification

GHS Label elements, including precautionary statements

  • Symbol(GHS)
  • Signal wordWarning
Precautionary statements
P362 Take off contaminated clothing and wash before reuse.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P321 Specific treatment (see … on this label).
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P264 Wash skin thouroughly after handling.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P264 Wash skin thouroughly after handling.
Hazard statements
H319 Causes serious eye irritation
H335 May cause respiratory irritation
H315 Causes skin irritation

SECTION 3: Composition/information on ingredients

Substance

  • Product name: Homosalate
  • Synonyms: Homosalate,HMS
  • CAS: 118-56-9
  • EC number: 204-260-8
  • MF: C16H22O3
  • MW: 262.34

SECTION 4: First aid measures

4.1 Description of first-aid measures

If inhaled
After inhalation: fresh air.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower.
In case of eye contact
After eye contact: rinse out with plenty of water. Remove contact lenses.
If swallowed
After swallowing: make victim drink water (two glasses at most). Consult doctor if feeling unwell.

4.2 Most important symptoms and effects, both acute and delayed

The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11

4.3 Indication of any immediate medical attention and special treatment needed

No data available

SECTION 5: Firefighting measures

5.1 Extinguishing media

Suitable extinguishing media
Foam Carbon dioxide (CO2) Dry powder
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.

5.2 Special hazards arising from the substance or mixture

Carbon oxides
Combustible.
Vapors are heavier than air and may spread along floors.
Forms explosive mixtures with air on intense heating.
Development of hazardous combustion gases or vapours possible in the event of fire.

5.3 Advice for firefighters

In the event of fire, wear self-contained breathing apparatus.

5.4 Further information

Prevent fire extinguishing water from contaminating surface water or the ground water system.

NFPA 704

2
0
0
HEALTH 2 Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury (e.g. diethyl ether, ammonium phosphate, iodine)
FIRE 0 Materials that will not burn under typical fire conditions, including intrinsically noncombustible materials such as concrete, stone, and sand. Materials that will not burn in air when exposed to a temperature of 820 °C (1,500 °F) for a period of 5 minutes.(e.g. Carbon tetrachloride)
REACT 0 Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2)
SPEC. HAZ.

SECTION 6: Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Advice for non-emergency personnel: Do not breathe vapors, aerosols. Evacuate the danger area, observe emergency procedures, consult an expert.
For personal protection see section 8.

6.2 Environmental precautions

Do not let product enter drains.

6.3 Methods and materials for containment and cleaning up

Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up with liquid-absorbent material (e.g. Chemizorb® ).
Dispose of properly. Clean up affected area.

6.4 Reference to other sections

For disposal see section 13.

SECTION 7: Handling and storage

7.1 Precautions for safe handling

For precautions see section 2.2.

7.2 Conditions for safe storage, including any incompatibilities

Storage conditions
Tightly closed.
Storage stability
Recommended storage temperature 2 - 8 °C

7.3 Specific end use(s)

Apart from the uses mentioned in section 1.2 no other specific uses are stipulated

SECTION 8: Exposure controls/personal protection

8.1 Control parameters

Ingredients with workplace control parameters

8.2 Exposure controls

Personal protective equipment
Eye/face protection
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses
Skin protection
not required
Respiratory protection
Not required; except in case of aerosol formation.
Control of environmental exposure
Do not let product enter drains.

SECTION 9: Physical and chemical properties

Information on basic physicochemical properties

  • a) AppearanceForm: liquid
    Color: colorless
  • b) Odorat 100.00%. mild menthol
  • c) Odor ThresholdNo data available
  • d) pHNo data available
  • e) Melting point/freezing pointFreezing point: < -20 °C - Regulation (EC) No. 440/2008,
    Annex, A.1
  • f) Initial boiling point and boiling range181 - 185 °C at 1.013 hPa
  • g) Flash point170,8 °C - closed cup - Regulation (EC) No. 440/2008, Annex,
    A.9
  • h) Evaporation rateNo data available
  • i) Flammability (solid, gas)No data available
  • j) Upper/lower flammability or explosive limitsNo data available
  • k) Vapor pressureca.0,013 hPa at 20 °C - Regulation (EC) No. 440/2008, Annex,
    A.4 ca.0,015 hPa at 15 °C - Regulation (EC) No. 440/2008, Annex,
    A.4
  • l) Vapor densityNo data available
  • m) Relative density1,05 at 20 °C - Regulation (EC) No. 440/2008, Annex, A.3
  • n) Water solubilityslightly soluble 0,4 g/l at 25 °C - Regulation (EC) No. 440/2008, Annex, A.6-
  • o) Partition coefficient: n-octanol/waterlog Pow: > 6 at 40 °C - Regulation (EC) No. 440/2008, Annex,
    A.8
  • p) Autoignition temperature402 °C at 1.004 - 1.023 hPa
  • q) Decomposition temperatureNo data available
  • r) ViscosityViscosity, kinematic: No data available
    Viscosity, dynamic: 85,1 mPa.s at 20 °C - OECD Test Guideline 114
  • s) Explosive propertiesNo data available
  • t) Oxidizing propertiesNo data available
  • SolubilityChloroform (Slightly), DMSO (Slightly)
  • Physical stateLiquid
  • ColourColourless

9.2 Other safety information

No data available

SECTION 10: Stability and reactivity

10.1 Reactivity

Forms explosive mixtures with air on intense heating.
A range from approx. 15 Kelvin below the flash point is to be rated as critical.

10.2 Chemical stability

The product is chemically stable under standard ambient conditions (room temperature) .

10.3 Possibility of hazardous reactions

No data available

10.4 Conditions to avoid

Strong heating.

10.5 Incompatible materials

Strong oxidizing agents

10.6 Hazardous decomposition products

In the event of fire: see section 5

SECTION 11: Toxicological information

11.1 Information on toxicological effects

Acute toxicity
LD50 Oral - Rat - > 5.000 mg/kg (OECD Test Guideline 401)
Inhalation: No data available
Dermal: No data available
Skin corrosion/irritation
Skin - EPISKIN Human Skin Model Test
Result: No skin irritation (OECD Test Guideline 439)
Serious eye damage/eye irritation
Classified based on available data. For more details, see section 2
Respiratory or skin sensitization
Maximization Test - Guinea pig
Result: Not a skin sensitizer.
(OECD Test Guideline 406)
Germ cell mutagenicity
Test Type: Ames test
Test system: Salmonella typhimurium
Metabolic activation: with and without metabolic activation
Method: Mutagenicity (Salmonella typhimurium - reverse mutation assay)
Result: negative
Test Type: In vitro mammalian cell gene mutation test
Test system: Chinese hamster lung cells
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 476
Result: negative
Test Type: Chromosome aberration test in vitro
Test system: Chinese hamster lung cells
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 473
Result: negative
Carcinogenicity
Classified based on available data. For more details, see section 2
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Classified based on available data. For more details, see section 2
Specific target organ toxicity - repeated exposure
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2

11.2 Additional Information

To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
Hazardous properties cannot be excluded but are unlikely when the product is handled appropriately.
Handle in accordance with good industrial hygiene and safety practice.

SECTION 12: Ecological information

12.1 Toxicity

Toxicity to fish static test LC50 - Danio rerio (zebra fish) - > 82 mg/l - 96 h (OECD Test Guideline 203)
Toxicity to daphnia static test EC50 - Daphnia magna (Water flea) - > 100 mg/l - 48 h and other aquatic (Regulation (EC) No. 440/2008, Annex, C.2) invertebrates
Toxicity to algae static test ErC50 - Pseudokirchneriella subcapitata - > 0,008 mg/l - 72 h (OECD Test Guideline 201)

12.2 Persistence and degradability

Biodegradability aerobic - Exposure time 28 d
Result: 70,2 % - Inherently biodegradable.
(OECD Test Guideline 302C)

12.3 Bioaccumulative potential

No data available

12.4 Mobility in soil

No data available

12.5 Results of PBT and vPvB assessment

This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

12.6 Other adverse effects

No data available

SECTION 13: Disposal considerations

13.1 Waste treatment methods

Product
See www.retrologistik.com for processes regarding the return of chemicals and containers, or contact us there if you have further questions.

SECTION 14: Transport information

14.1 UN number

ADR/RID: -
IMDG: -
IATA: -

14.2 UN proper shipping name

ADR/RID: Not dangerous goods
IMDG: Not dangerous goods
IATA: Not dangerous goods

14.3 Transport hazard class(es)

ADR/RID: -
IMDG: -
IATA: -

14.4 Packaging group

ADR/RID: -
IMDG: -
IATA: -

14.5 Environmental hazards

ADR/RID: no
IMDG Marine pollutant: no
IATA: no

14.6 Special precautions for user

Further information: Not classified as dangerous in the meaning of transport regulations.

SECTION 15: Regulatory information

15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture

This material safety data sheet complies with the requirements of Regulation (EC) No.
1907/2006.
National legislation
Seveso III: Directive 2012/18/EU of the : Not applicable
European Parliament and of the Council on the control of major-accident hazards involving dangerous substances.

15.2 Chemical Safety Assessment

For this product a chemical safety assessment was not carried out

SECTION 16: Other information

Abbreviations and acronyms

CAS: Chemical Abstracts Service
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
Disclaimer:

The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.

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