Chemical Safety Data Sheet MSDS / SDS
Isobutylene oxide
Revision Date:2026-03-21Revision Number:1
Product identifier
- Product name: Isobutylene oxide
- CBnumber: CB9460926
- CAS: 558-30-5
- EINECS Number: 209-193-8
- Synonyms: 2,2-DIMETHYLOXIRANE;2-Methyl-1,2-epoxypropane
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 010-86108875
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
P202 Do not handle until all safety precautions have been read and understood.
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
Hazard statements
H225 Highly Flammable liquid and vapour
H314 Causes severe skin burns and eye damage
H341 Suspected of causing genetic defects
H351 Suspected of causing cancer
Substance
- Product name: Isobutylene oxide
- Synonyms: 2,2-DIMETHYLOXIRANE;2-Methyl-1,2-epoxypropane
- CAS: 558-30-5
- EC number: 209-193-8
- MF: C4H8O
- MW: 72.11
4.1 Description of first-aid measures
General adviceFirst aiders need to protect themselves. Show this material safety data sheet to the doctor in attendance.
If inhaled
After inhalation: fresh air. Call in physician.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. Call a physician immediately.
In case of eye contact
After eye contact: rinse out with plenty of water. Immediately call in ophthalmologist.
Remove contact lenses.
If swallowed
Remove contact lenses.
After swallowing: make victim drink water (two glasses at most), avoid vomiting (risk of perforation). Call a physician immediately. Do not attempt to neutralise.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available
4.4 Notes to physician
No data available
5.1 Extinguishing media
Suitable extinguishing mediaCarbon dioxide (CO2) Dry powder
Unsuitable extinguishing media
Foam Water
5.2 Special hazards arising from the substance or mixture
Carbon oxides
Combustible.
Pay attention to flashback.
Vapors are heavier than air and may spread along floors.
Development of hazardous combustion gases or vapours possible in the event of fire.
Forms explosive mixtures with air at ambient temperatures.
Combustible.
Pay attention to flashback.
Vapors are heavier than air and may spread along floors.
Development of hazardous combustion gases or vapours possible in the event of fire.
Forms explosive mixtures with air at ambient temperatures.
5.3 Advice for firefighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
Remove container from danger zone and cool with water. Prevent fire extinguishing water from contaminating surface water or the ground water system.
Remove container from danger zone and cool with water. Prevent fire extinguishing water from contaminating surface water or the ground water system.
NFPA 704
3
3
0
| HEALTH | 3 | Short exposure could cause serious temporary or moderate residual injury (e.g. liquid hydrogen, sulfuric acid, calcium hypochlorite, hexafluorosilicic acid) | |
| FIRE | 3 | Liquids and solids (including finely divided suspended solids) that can be ignited under almost all ambient temperature conditions . Liquids having a flash point below 22.8 °C (73 °F) and having a boiling point at or above 37.8 °C (100 °F) or having a flash point between 22.8 and 37.8 °C (73 and 100 °F). (e.g. gasoline, acetone) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
6.1 Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Keep away from heat and sources of ignition.
Evacuate the danger area, observe emergency procedures, consult an expert.
For personal protection see section 8.
Evacuate the danger area, observe emergency procedures, consult an expert.
For personal protection see section 8.
6.2 Environmental precautions
Do not let product enter drains. Risk of explosion.
6.3 Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up carefully with liquid-absorbent material (e.g.
Chemizorb®). Dispose of properly. Clean up affected area.
Chemizorb®). Dispose of properly. Clean up affected area.
6.4 Reference to other sections
For disposal see section 13.
7.1 Precautions for safe handling
Advice on safe handlingWork under hood. Do not inhale substance/mixture. Avoid generation of vapours/aerosols.
Advice on protection against fire and explosion
Keep away from open flames, hot surfaces and sources of ignition.Take precautionary measures against static discharge.
Hygiene measures
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
For precautions see section 2.2.
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Storage conditionsKeep container tightly closed in a dry and well-ventilated place. Keep away from heat and sources of ignition.
Storage class
Storage class (TRGS 510): 3: Flammable liquids
8.1 Control parameters
Ingredients with workplace control parametersContains no substances with occupational exposure limit values.
8.2 Exposure controls
Appropriate engineering controlsImmediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
Personal protective equipment
Eye/face protection
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Tightly fitting safety goggles
Skin protection
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN 16523-1 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell,
Internet: www.kcl.de).
Splash contact
Material: butyl-rubber
Minimum layer thickness: 0.7 mm
Break through time: 30 min
Material tested:Butoject® (KCL 898)
Body Protection
Internet: www.kcl.de).
Splash contact
Material: butyl-rubber
Minimum layer thickness: 0.7 mm
Break through time: 30 min
Material tested:Butoject® (KCL 898)
Flame retardant antistatic protective clothing.
Respiratory protection
required when vapours/aerosols are generated. Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Control of environmental exposure
Do not let product enter drains. Risk of explosion.
Information on basic physicochemical properties
- a) Physical stateliquid
- b) Colorcolorless
- c) OdorNo data available
- d) Melting point/freezing pointMelting point/range: -66.1 °C
- e) Initial boiling point and boiling range50 - 51 °C - lit.
- f) Flammability (solid, gas)No data available
- g) Upper/lower flammability or explosive limits1.5-13.5%(V)
- h) Flash point-32.5 °C
- i) Autoignition temperature345 °C
- j) Decomposition temperatureNo data available
- k) pHNo data available
- l) ViscosityViscosity, kinematic: No data available
Viscosity, dynamic: No data available - m) Water solubility58 g/l at 20 °C
- n) Partition coefficient n-octanol/waterlog Pow: 0.83
- o) Vapor pressure270 hPa at 15.2 °C 387.9 hPa at 24.7 °C
- p) Density0.812 g/cm3 at 25 °C - lit.
- Relative density0.812 g/mL at 25 °C(lit.)
- q) Relative vapor densityNo data available
- r) Particle characteristicsNo data available
- s) Explosive propertiesNo data available
- t) Oxidizing propertiesNo data available
- Solubility58g/l
9.2 Other safety information
No data available
10.1 Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
10.2 Possibility of hazardous reactions
Violent reactions possible with:
Water acids
Water acids
10.3 Conditions to avoid
Avoid moisture.
Warming.
Warming.
10.4 Incompatible materials
No data available
10.5 Hazardous decomposition products
In the event of fire: see section 5
11.1 Information on toxicological effects
Acute toxicityLD50 Oral - Rat - male and female - 3,890 mg/kg (OECD Test Guideline 401)
Inhalation: No data available
LD50 Dermal - Acute toxicity estimate - male and female - > 4,000 mg/kg (OECD Test Guideline 402)
Skin corrosion/irritation
Inhalation: No data available
LD50 Dermal - Acute toxicity estimate - male and female - > 4,000 mg/kg (OECD Test Guideline 402)
Skin - Rabbit
Result: Corrosive (OECD Test Guideline 404)
Serious eye damage/eye irritation
Result: Corrosive (OECD Test Guideline 404)
Remarks: No data available
Respiratory or skin sensitization
Classified based on available data. For more details, see section 2
Germ cell mutagenicity
Test Type: reverse mutation assay
Test system: Salmonella typhimurium
Metabolic activation: with and without metabolic activation
Method: Mutagenicity (Salmonella typhimurium - reverse mutation assay)
Result: negative
Carcinogenicity
Test system: Salmonella typhimurium
Metabolic activation: with and without metabolic activation
Method: Mutagenicity (Salmonella typhimurium - reverse mutation assay)
Result: negative
Classified based on available data. For more details, see section 2
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Classified based on available data. For more details, see section 2
Specific target organ toxicity - repeated exposure
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2
11.2 Additional Information
RTECS: TZ3580000
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
12.1 Toxicity
No data available
Toxicity to daphnia static test EC50 - Daphnia magna (Water flea) - 64.8 mg/l - 48 h and other aquatic invertebrates
Toxicity to algae Remarks: No data available
Toxicity to bacteria
Remarks: No data available
Toxicity to daphnia static test EC50 - Daphnia magna (Water flea) - 64.8 mg/l - 48 h and other aquatic invertebrates
Toxicity to algae Remarks: No data available
Toxicity to bacteria
Remarks: No data available
12.2 Persistence and degradability
Biodegradability
Result: 90 - 100 % - Readily biodegradable.
(OECD Test Guideline 310)
Result: 90 - 100 % - Readily biodegradable.
(OECD Test Guideline 310)
12.3 Bioaccumulative potential
No data available
12.4 Mobility in soil
No data available
12.5 Results of PBT and vPvB assessment
PBT/vPvB assessment not available as chemical safety assessment not required/not conducted
12.6 Endocrine disrupting properties
No data available
12.7 Other adverse effects
No data available
13.1 Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company.
Offer surplus and non-recyclable solutions to a licensed disposal company.
14.1 UN number
ADR/RID: 1993
IMDG: 1993
IATA-DGR: 1993
IMDG: 1993
IATA-DGR: 1993
14.2 UN proper shipping name
ADR/RID: FLAMMABLE LIQUID, N.O.S. (2,2-Dimethyloxirane) (2,2-Dimethyloxirane)
IMDG: FLAMMABLE LIQUID, N.O.S. (2,2-Dimethyloxirane) (2,2-Dimethyloxirane)
IATA-DGR: Flammable liquid, n.o.s. (2,2-Dimethyloxirane) (2,2-Dimethyloxirane)
IMDG: FLAMMABLE LIQUID, N.O.S. (2,2-Dimethyloxirane) (2,2-Dimethyloxirane)
IATA-DGR: Flammable liquid, n.o.s. (2,2-Dimethyloxirane) (2,2-Dimethyloxirane)
14.3 Transport hazard class(es)
ADR/RID: 3
IMDG: 3
IATA-DGR: 3
IMDG: 3
IATA-DGR: 3
14.4 Packaging group
ADR/RID: II
IMDG: II
IATA-DGR: II
IMDG: II
IATA-DGR: II
14.5 Environmental hazards
ADR/RID: no
IMDG Marine pollutant: no
IATA-DGR: no
IMDG Marine pollutant: no
IATA-DGR: no
14.6 Special precautions for user
Based on chemical properties, choose appropriate tools and conditions of transport.
Transporting tools shall be equipped with appropriate and sufficient firefighting equipment and emergency leaking installations. If transporting by road, please go along the specified route.
Transporting tools shall be equipped with appropriate and sufficient firefighting equipment and emergency leaking installations. If transporting by road, please go along the specified route.
14.7 Incompatible materials
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
National regulatory information
Regulations on Safety Management of Hazardous Chemicals
Catalogue of Hazardous Chemicals : Listed
Regulation of Environmental Management on the First Import of Chemicals and the Import and Export of Toxic Chemicals
China Severely Restricted Toxic Chemicals for : Listed
Import and Export
Measures on the Environmental Administration of New Chemical Substances Registration
Registration/Notification number : B1A222225568
Downstream users need to comply with the conditions of safe use of the chemical, understand the environmental and health hazard and risk management measures identified on the SDS as well as the local/national regulations concerning the chemical.
Other regulations
Please pay attention on the waste treatment should also comply with local regulations requirement.
Regulations on Safety Management of Hazardous Chemicals
Catalogue of Hazardous Chemicals : Listed
Regulation of Environmental Management on the First Import of Chemicals and the Import and Export of Toxic Chemicals
China Severely Restricted Toxic Chemicals for : Listed
Import and Export
Measures on the Environmental Administration of New Chemical Substances Registration
Registration/Notification number : B1A222225568
Downstream users need to comply with the conditions of safe use of the chemical, understand the environmental and health hazard and risk management measures identified on the SDS as well as the local/national regulations concerning the chemical.
Other regulations
Please pay attention on the waste treatment should also comply with local regulations requirement.
Abbreviations and acronyms
CAS: Chemical Abstracts Service
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
Disclaimer:
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.