Chemical Safety Data Sheet MSDS / SDS
Nandrolone
Revision Date:2026-03-21Revision Number:1
Product identifier
- Product name: Nandrolone
- CBnumber: CB5681525
- CAS: 434-22-0
- EINECS Number: 207-101-0
- Synonyms: 19-NORTESTOSTERONE;nortestosterone
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 010-86108875
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
P501 Dispose of contents/container to..…
P405 Store locked up.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P202 Do not handle until all safety precautions have been read and understood.
P201 Obtain special instructions before use.
Hazard statements
H351 Suspected of causing cancer
Substance
- Product name: Nandrolone
- Synonyms: 19-NORTESTOSTERONE;nortestosterone
- CAS: 434-22-0
- EC number: 207-101-0
- MF: C18H26O2
- MW: 274.4
4.1 Description of first-aid measures
General adviceShow this material safety data sheet to the doctor in attendance.
If inhaled
After inhalation: fresh air. If breathing stops: mouth-to-mouth breathing or artificial respiration. Oxygen if necessary. Immediately call in physician.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. Consult a physician.
In case of eye contact
After eye contact: rinse out with plenty of water. Call in ophthalmologist. Remove contact lenses.
If swallowed
After swallowing: immediately make victim drink water (two glasses at most). Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available
4.4 Notes to physician
No data available
5.1 Extinguishing media
Suitable extinguishing mediaFoam Carbon dioxide (CO2) Dry powder
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.
5.2 Special hazards arising from the substance or mixture
Carbon oxides
Nitrogen oxides (NOx)
Combustible.
Pay attention to flashback.
Vapors are heavier than air and may spread along floors.
Development of hazardous combustion gases or vapours possible in the event of fire.
Forms explosive mixtures with air at ambient temperatures.
Nitrogen oxides (NOx)
Combustible.
Pay attention to flashback.
Vapors are heavier than air and may spread along floors.
Development of hazardous combustion gases or vapours possible in the event of fire.
Forms explosive mixtures with air at ambient temperatures.
5.3 Advice for firefighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
Remove container from danger zone and cool with water. Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.
Remove container from danger zone and cool with water. Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.
NFPA 704
3
0
0
| HEALTH | 3 | Short exposure could cause serious temporary or moderate residual injury (e.g. liquid hydrogen, sulfuric acid, calcium hypochlorite, hexafluorosilicic acid) | |
| FIRE | 0 | Materials that will not burn under typical fire conditions, including intrinsically noncombustible materials such as concrete, stone, and sand. Materials that will not burn in air when exposed to a temperature of 820 °C (1,500 °F) for a period of 5 minutes.(e.g. Carbon tetrachloride) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
6.1 Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Keep away from heat and sources of ignition.
Evacuate the danger area, observe emergency procedures, consult an expert.
For personal protection see section 8.
Evacuate the danger area, observe emergency procedures, consult an expert.
For personal protection see section 8.
6.2 Environmental precautions
Do not let product enter drains. Risk of explosion.
6.3 Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up with liquid-absorbent material (e.g. Chemizorb® ).
Dispose of properly. Clean up affected area.
Dispose of properly. Clean up affected area.
6.4 Reference to other sections
For disposal see section 13.
7.1 Precautions for safe handling
Advice on safe handlingWork under hood. Do not inhale substance/mixture. Avoid generation of vapours/aerosols.
Advice on protection against fire and explosion
Keep away from open flames, hot surfaces and sources of ignition.Take precautionary measures against static discharge.
Hygiene measures
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
For precautions see section 2.2.
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Storage conditionsKeep container tightly closed in a dry and well-ventilated place. Keep away from heat and sources of ignition.
Storage stabilityRecommended storage temperature
-20 °C
Storage class
Storage class (TRGS 510): 3: Flammable liquids
8.1 Control parameters
Ingredients with workplace control parameters| ['Component', 'CAS-No.', 'Value', 'Control\nparameters', 'Basis'] | ['Acetonitrile', '75-05-8', 'PC-TWA', '30 mg/m3', 'Occupational exposure limits for\nhazardous agents in the\nworkplace - Chemical\nhazardous agents.'] | ['', 'Remarks', 'Skin', None, None] |
|---|
8.2 Exposure controls
Appropriate engineering controlsImmediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
Personal protective equipment
Eye/face protection
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses
Skin protection
required
Body Protection
Flame retardant antistatic protective clothing.
Respiratory protection
required when vapours/aerosols are generated.
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Control of environmental exposure
Do not let product enter drains. Risk of explosion.
Information on basic physicochemical properties
- a) Physical stateliquid
- b) ColorDimorphic crystals from CH2Cl2/Et2O
- c) OdorNo data available
- d) Melting point/freezing pointNo data available
- e) Initial boiling point and boiling range81 - 82 °C at 1.013 hPa
- f) Flammability (solid, gas)No data available
- g) Upper/lower flammability or explosive limitsUpper explosion limit: 16 %(V)
Lower explosion limit: 4.4 %(V) - h) Flash point2 °C - closed cup
- i) Autoignition temperatureNo data available
- j) Decomposition temperatureNo data available
- k) pHNo data available
- l) ViscosityViscosity, kinematic: No data available
Viscosity, dynamic: No data available - m) Water solubility3.09g/L(25 ºC)
- n) Partition coefficient n-octanol/waterNo data available
- o) Vapor pressureNo data available
- p) Density0.782 g/cm3 at 20 °C
- Relative density1.0528 (rough estimate)
- q) Relative vapor densityNo data available
- r) Particle characteristicsNo data available
- s) Explosive propertiesNot classified as explosive.
- t) Oxidizing propertiesnone
- SolubilityAcetonitrile: 1 mg/ml; Ethanol: 1 mg/ml; Methanol: 1 mg/ml
9.2 Other safety information
No data available
10.1 Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
10.2 Possibility of hazardous reactions
No data available
10.3 Conditions to avoid
Warming.
10.4 Incompatible materials
acids, Bases, Oxidizing agents, Alkali metals
10.5 Hazardous decomposition products
In the event of fire: see section 5
11.1 Information on toxicological effects
Mixture Acute toxicityOral: No data available
Acute toxicity estimate Inhalation - 4 h - 11.01 mg/l - vapor(Calculation method)
Symptoms: Possible symptoms:, mucosal irritations
Acute toxicity estimate Dermal - 1,502 mg/kg (Calculation method)
Skin corrosion/irritation
Acute toxicity estimate Inhalation - 4 h - 11.01 mg/l - vapor(Calculation method)
Symptoms: Possible symptoms:, mucosal irritations
Acute toxicity estimate Dermal - 1,502 mg/kg (Calculation method)
Classified based on available data. For more details, see section 2
Serious eye damage/eye irritation
Remarks: Mixture causes serious eye irritation.
Respiratory or skin sensitization
Classified based on available data. For more details, see section 2
Germ cell mutagenicity
Classified based on available data. For more details, see section 2
Carcinogenicity
Classified based on available data. For more details, see section 2
Reproductive toxicity
May harm the unborn child.
May impair fertility.
Specific target organ toxicity - single exposure
May impair fertility.
Classified based on available data. For more details, see section 2
Specific target organ toxicity - repeated exposure
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2
11.2 Additional Information
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
Treat as cyanide poisoning., Always have on hand a cyanide first-aid kit, together with proper instructions., The onset of symptoms is generally delayed pending conversion to cyanide., Nausea, Vomiting, Diarrhea, Headache, Dizziness, Rash, Cyanosis
Other dangerous properties can not be excluded.
Handle in accordance with good industrial hygiene and safety practice.
Components Acetonitrile
Treat as cyanide poisoning., Always have on hand a cyanide first-aid kit, together with proper instructions., The onset of symptoms is generally delayed pending conversion to cyanide., Nausea, Vomiting, Diarrhea, Headache, Dizziness, Rash, Cyanosis
Other dangerous properties can not be excluded.
Handle in accordance with good industrial hygiene and safety practice.
Acute toxicity
LD50 Oral - Mouse - male and female - 617 mg/kg (OECD Test Guideline 401)
LC50 Inhalation - Mouse - male and female - 4 h - 6.022 mg/l - vapor (OECD Test Guideline 403)
Acute toxicity estimate Dermal - 1,500 mg/kg (Expert judgment)
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
LC50 Inhalation - Mouse - male and female - 4 h - 6.022 mg/l - vapor (OECD Test Guideline 403)
Acute toxicity estimate Dermal - 1,500 mg/kg (Expert judgment)
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Skin corrosion/irritation
Skin - Rabbit
Result: No skin irritation - 4 h (OECD Test Guideline 404)
Result: No skin irritation - 4 h (OECD Test Guideline 404)
Serious eye damage/eye irritation
Eyes - Rabbit
Result: Causes serious eye irritation.
(OECD Test Guideline 405)
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Result: Causes serious eye irritation.
(OECD Test Guideline 405)
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Respiratory or skin sensitization
Buehler Test - Guinea pig
Result: negative (OECD Test Guideline 406)
Result: negative (OECD Test Guideline 406)
Germ cell mutagenicity
Test Type: Ames test
Test system: S. typhimurium
Result: negative
Remarks: (ECHA)
Test Type: In vitro mammalian cell gene mutation test
Test system: Chinese hamster ovary cells
Result: negative
Test Type: Mutagenicity (mammal cell test): chromosome aberration.
Test system: Chinese hamster ovary cells
Result: Positive results were obtained in some in vitro tests.
Remarks: (National Toxicology Program)
Test Type: sister chromatid exchange assay
Test system: Chinese hamster ovary cells
Result: negative
Remarks: Sister chromatid exchange
Test system: Saccharomyces cerevisiae
Result: positive
Remarks: Cytogenetic analysis (ECHA)
Test Type: In vitro mammalian cell gene mutation test
Test system: Mouse lymphoma test
Result: negative
Method: OECD Test Guideline 474
Species: Mouse - male and female
Result: negative
Carcinogenicity
Test system: S. typhimurium
Result: negative
Remarks: (ECHA)
Test Type: In vitro mammalian cell gene mutation test
Test system: Chinese hamster ovary cells
Result: negative
Test Type: Mutagenicity (mammal cell test): chromosome aberration.
Test system: Chinese hamster ovary cells
Result: Positive results were obtained in some in vitro tests.
Remarks: (National Toxicology Program)
Test Type: sister chromatid exchange assay
Test system: Chinese hamster ovary cells
Result: negative
Remarks: Sister chromatid exchange
Test system: Saccharomyces cerevisiae
Result: positive
Remarks: Cytogenetic analysis (ECHA)
Test Type: In vitro mammalian cell gene mutation test
Test system: Mouse lymphoma test
Result: negative
Method: OECD Test Guideline 474
Species: Mouse - male and female
Result: negative
No evidence of carcinogenicity in animal studies.
Reproductive toxicity
Animal testing did not show any effects on fertility.
Specific target organ toxicity - single exposure
The substance or mixture is not classified as specific target organ toxicant, single exposure.
Specific target organ toxicity - repeated exposure
The substance or mixture is not classified as specific target organ toxicant, repeated exposure.
Aspiration hazard
No aspiration toxicity classification
Nandrolone Acute toxicity
Oral: No data available
Inhalation: No data available
Dermal: No data available
Skin corrosion/irritation
Inhalation: No data available
Dermal: No data available
Classified based on available data. For more details, see section 2
Serious eye damage/eye irritation
Classified based on available data. For more details, see section 2
Respiratory or skin sensitization
Classified based on available data. For more details, see section 2
Germ cell mutagenicity
Classified based on available data. For more details, see section 2
Carcinogenicity
Suspected of causing cancer.
Reproductive toxicity
May damage the unborn child.
May damage fertility.
Specific target organ toxicity - single exposure
May damage fertility.
Classified based on available data. For more details, see section 2
Specific target organ toxicity - repeated exposure
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2
12.1 Toxicity
MixtureNo data available
12.2 Persistence and degradability
No data available
12.3 Bioaccumulative potential
No data available
12.4 Mobility in soil
No data available
12.5 Results of PBT and vPvB assessment
PBT/vPvB assessment not available as chemical safety assessment not required/not conducted
12.6 Endocrine disrupting properties
No data available
12.7 Other adverse effects
No data available
Components Acetonitrile
Toxicity to fish flow-through test LC50 - Pimephales promelas (fathead minnow) - 1,640 mg/l - 96 h
Remarks: (ECHA)
Toxicity to algae static test NOEC - Phaeodactylum tricornutum - 400 mg/l - 72 h (ISO 10253) static test ErC50 - Phaeodactylum tricornutum - 9,696 mg/l - 72 h (ISO 10253)
Toxicity to bacteria
Toxicity to flow-through test NOEC - Oryzias latipes - 102 mg/l - 21 d fish(Chronic toxicity) (OECD Test Guideline 204)
Nandrolone
Remarks: (ECHA)
Toxicity to algae static test NOEC - Phaeodactylum tricornutum - 400 mg/l - 72 h (ISO 10253) static test ErC50 - Phaeodactylum tricornutum - 9,696 mg/l - 72 h (ISO 10253)
Toxicity to bacteria
Toxicity to flow-through test NOEC - Oryzias latipes - 102 mg/l - 21 d fish(Chronic toxicity) (OECD Test Guideline 204)
No data available
13.1 Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company.
Offer surplus and non-recyclable solutions to a licensed disposal company.
14.1 UN number
ADR/RID: 1648
IMDG: 1648
IATA-DGR: 1648
IMDG: 1648
IATA-DGR: 1648
14.2 UN proper shipping name
ADR/RID: ACETONITRILE,SOLUTION
IMDG: ACETONITRILE,SOLUTION
IATA-DGR: Acetonitrile,SOLUTION
IMDG: ACETONITRILE,SOLUTION
IATA-DGR: Acetonitrile,SOLUTION
14.3 Transport hazard class(es)
ADR/RID: 3
IMDG: 3
IATA-DGR: 3
IMDG: 3
IATA-DGR: 3
14.4 Packaging group
ADR/RID: II
IMDG: II
IATA-DGR: II
IMDG: II
IATA-DGR: II
14.5 Environmental hazards
ADR/RID: no
IMDG Marine pollutant: no
IATA-DGR: no
IMDG Marine pollutant: no
IATA-DGR: no
14.6 Special precautions for user
Based on chemical properties, choose appropriate tools and conditions of transport.
Transporting tools shall be equipped with appropriate and sufficient firefighting equipment and emergency leaking installations. If transporting by road, please go along the specified route.
Transporting tools shall be equipped with appropriate and sufficient firefighting equipment and emergency leaking installations. If transporting by road, please go along the specified route.
14.7 Incompatible materials
acids, Bases, Oxidizing agents, Alkali metals
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
National regulatory information
Law on the Prevention and Control of Occupational Diseases
Regulations on Safety Management of Hazardous Chemicals
Catalogue of Hazardous Chemicals : Listed
Measures on the Environmental Administration of New Chemical Substances Registration
Registration/Notification number : B1A222212774
Downstream users need to comply with the conditions of safe use of the chemical, understand the environmental and health hazard and risk management measures identified on the SDS as well as the local/national regulations concerning the chemical.
Other regulations
Please pay attention on the waste treatment should also comply with local regulations requirement.
Law on the Prevention and Control of Occupational Diseases
Regulations on Safety Management of Hazardous Chemicals
Catalogue of Hazardous Chemicals : Listed
Measures on the Environmental Administration of New Chemical Substances Registration
Registration/Notification number : B1A222212774
Downstream users need to comply with the conditions of safe use of the chemical, understand the environmental and health hazard and risk management measures identified on the SDS as well as the local/national regulations concerning the chemical.
Other regulations
Please pay attention on the waste treatment should also comply with local regulations requirement.
Abbreviations and acronyms
CAS: Chemical Abstracts Service
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
Disclaimer:
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.