Chemical Safety Data Sheet MSDS / SDS
Nerolidol
Revision Date:2026-03-21Revision Number:1
Product identifier
- Product name: Nerolidol
- CBnumber: CB2206877
- CAS: 7212-44-4
- EINECS Number: 230-597-5
- Synonyms: 1,6,10-dodecatrien-3-ol,3,7,11-trimethyl- ;nerolido
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 010-86108875
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordWarning
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P273 Avoid release to the environment.
P264 Wash skin thouroughly after handling.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
Hazard statements
H410 Very toxic to aquatic life with long lasting effects
H319 Causes serious eye irritation
H317 May cause an allergic skin reaction
Substance
- Product name: Nerolidol
- Synonyms: 1,6,10-dodecatrien-3-ol,3,7,11-trimethyl- ;nerolido
- CAS: 7212-44-4
- EC number: 230-597-5
- MF: C15H26O
- MW: 222.37
General advice
Show this safety data sheet to the doctor in attendance.
If inhaled
After inhalation: fresh air.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. Consult a physician.
In case of eye contact
After eye contact: rinse out with plenty of water. Call in ophthalmologist. Remove contact lenses.
If swallowed
After swallowing: immediately make victim drink water (two glasses at most). Consult a physician.
Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11
Protection of first-aiders
For personal protection see section 8.
Notes to physician
No data available
Suitable extinguishing media
Carbon dioxide (CO2) Foam Dry powder
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.
Specific hazards during fire fighting
Combustible. Vapours are heavier than air and may spread along floors. Forms explosive mixtures with air on intense heating. Development of hazardous combustion gases or vapours possible in the event of fire.
Hazardous combustion products
Carbon oxides
Specific extinguishing methods
Prevent fire extinguishing water from contaminating surface water or the ground water system.
Special protective equipment for fire-fighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
NFPA 704
1
1
0
| HEALTH | 1 | Exposure would cause irritation with only minor residual injury (e.g. acetone, sodium bromate, potassium chloride) | |
| FIRE | 1 | Materials that require considerable preheating, under all ambient temperature conditions, before ignition and combustion can occur. Includes some finely divided suspended solids that do not require heating before ignition can occur. Flash point at or above 93.3 °C (200 °F). (e.g. mineral oil, ammonia) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Do not breathe vapours, aerosols. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert. Advice for emergency responders: For personal protection see section 8.
Environmental precautions
Do not let product enter drains.
Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up with liquid-absorbent material (e.g. Chemizorb® ). Dispose of properly. Clean up affected area.
Handling
Avoidance of contactStrong oxidizing agents
Storage
Further information on storage conditionsTightly closed.
Storage class
10, Combustible liquids
Recommended storage temperature
Recommended storage temperature see product label.
Ingredients with workplace control parameters
Contains no substances with occupational exposure limit values.
Engineering measures
No data available
Personal protective equipment
Respiratory protectionrequired when vapours/aerosols are generated.
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Recommended Filter
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Filter A (acc. to DIN 3181) for vapours of organic
type
compounds
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.
Eye/face protection
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Safety glasses
Skin and body protection
Safety glasses
protective clothing
Hand protection
Material
Nitrile rubber
Break through time
480 min
Glove thickness
0.4 mm
Protective index
Full contact
Manufacturer
Camatril® (KCL 730 / Aldrich Z677442, Size M)
Material
butyl-rubber
Break through time
120 min
Glove thickness
0.7 mm
Protective index
Splash contact
Manufacturer
Butoject® (KCL 898)
Remarks
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN 16523-1 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D- 36124 Eichenzell, Internet: www.kcl.de).
Hygiene measures
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
Information on basic physicochemical properties
- Solubility0.014g/l, Very slightly soluble in water, soluble in alcohol and oils.
- Physical stateLiquid
- Particle characteristics Particle sizeNo data available
- Molecular weight222.37 g/mol
- Oxidizing propertiesnone
- Explosive propertiesNo data available
- Flow timeNo data available
- Viscosity, kinematic15.8 mm2/s ( 20 °C)
Method: OECD Test Guideline 114
GLP: yes - Viscosity, dynamic13.8 mPa.s ( 20 °C)
Method: OECD Test Guideline 114
GLP: yes - Autoignition temperature230 °C
Decomposition temperature Viscosity: No data available - Partition coefficient: n-octanol/waterlog Pow: 4.5 (24 °C)
Method: Regulation (EC) No. 440/2008, Annex, A.8 - Water solubility0.0141 g/l (20 °C)
Method: Regulation (EC) No. 440/2008, Annex, A.6
GLP: yes - Density0.875 g/cm3 (25 °C)
Method: lit. - Relative density0.875 g/mL at 25 °C (lit.)
- Relative vapor densityNo data available
- Vapor pressure< 0.1 hPa (20 °C)
Method: OECD Test Guideline 104
GLP: yes - Lower explosion limit / Lower flammability limit0.7-4.5%(V)
- Upper explosion limit / Upper flammability limit0.7-4.5%(V)
- Burning rateNo data available
- Flammability (liquids)No data available
- Flammability (solid, gas)No data available
- Evaporation rateNo data available
- Flash point128 °C (1,013 hPa)
Method: ISO 2719, closed cup
GLP: yes - Boiling point/boiling range114 °C (1 hPa)
Method: lit. - Melting point/ range-90 °C point Method: OECD Test Guideline 102
GLP: yes - pHNo data available
- Odor ThresholdNo data available
- Odorat 100.00 %. floral green waxy citrus woody
- Colorcolourless
- Appearanceliquid (20 °C , 1,013 hPa)
Reactivity
Forms explosive mixtures with air on intense heating. A range from approx. 15 Kelvin below the flash point is to be rated as critical.
Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
Contains the following stabiliser(s):
DL-α-Tocopherol (>=0.05 - <=0.2 %)
Possibility of hazardous reactions
Violent reactions possible with: acids
Conditions to avoid
Strong heating.
Incompatible materials
Strong oxidizing agents
Hazardous decomposition products
In the event of fire: see section 5
11.1 Information on toxicological effects
Acute toxicityLD50 Oral - Rat - male and female - > 2,610 mg/kg (OECD Test Guideline 401)
Inhalation: No data available
LD50 Dermal - Rabbit - > 5,000 mg/kg
Remarks: (ECHA)
Skin corrosion/irritation
Inhalation: No data available
LD50 Dermal - Rabbit - > 5,000 mg/kg
Remarks: (ECHA)
Skin - Rabbit
Result: No skin irritation - 4 h (OECD Test Guideline 404)
Serious eye damage/eye irritation
Result: No skin irritation - 4 h (OECD Test Guideline 404)
Eyes - Rabbit
Result: Irritating to eyes. - 8 d (OECD Test Guideline 405)
Respiratory or skin sensitization
Result: Irritating to eyes. - 8 d (OECD Test Guideline 405)
Local lymph node assay (LLNA) - Mouse
Result: Causes sensitisation.
(OECD Test Guideline 429)
Germ cell mutagenicity
Result: Causes sensitisation.
(OECD Test Guideline 429)
Test Type: Ames test
Test system: S. typhimurium
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 471
Result: negative
Carcinogenicity
Test system: S. typhimurium
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 471
Result: negative
Classified based on available data. For more details, see section 2
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Classified based on available data. For more details, see section 2
Specific target organ toxicity - repeated exposure
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2
11.2 Additional Information
RTECS: JR4977000
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
Ecotoxicity
Components:
3,7,11-Trimethyldodeca-1,6,10-trien-3-ol,mixed isomers:
Toxicity to fishLC50 (Pimephales promelas (fathead minnow)): 1.43 mg/l End point: mortality Exposure time: 96 h Test Type: flow-through test NOEC (Pimephales promelas (fathead minnow)): 0.64 mg/l End point: mortality Exposure time: 96 h Test Type: flow-through test
Toxicity to daphnia and other aquatic invertebrates
EC50 (Daphnia magna (Water flea)): 0.5103 mg/l End point: Immobilization Exposure time: 48 h Test Type: static test Method: Regulation (EC) No. 440/2008, Annex, C.2
Toxicity to algae/aquatic plants
EC50 (Desmodesmus subspicatus (green algae)): 2 mg/l Exposure time: 72 h Test Type: static test Method: OECD Test Guideline 201 GLP: yes NOEC (Desmodesmus subspicatus (green algae)): 0.44 mg/l Exposure time: 72 h Test Type: static test Method: OECD Test Guideline 201 GLP: yes
M-Factor (Acute aquatic toxicity)
1
M-Factor (Chronic aquatic toxicity)
1
Toxicity to microorganisms
EC50 (activated sludge): > 1,000 mg/l Exposure time: 0.5 h Test Type: static test Method: OECD Test Guideline 209
DL-α-Tocopherol:
Toxicity to fishLC50 (Oncorhynchus mykiss (rainbow trout)): > 100 mg/l End point: mortality Exposure time: 96 h Test Type: static test Analytical monitoring: yes Method: OECD Test Guideline 203 GLP: yes The value is given in analogy to the following substances: dl-α-Tocopherolacetate
Toxicity to daphnia and other aquatic invertebrates
EC50 (Daphnia magna (Water flea)): > 23.53 mg/l Exposure time: 48 h Test Type: static test Analytical monitoring: yes Method: OECD Test Guideline 202 GLP: yes
Toxicity to algae/aquatic plants
ErC50 (Pseudokirchneriella subcapitata (green algae)): > 25.8 mg/l Exposure time: 72 h Test Type: static test Analytical monitoring: yes Method: OECD Test Guideline 201 GLP: yes
Toxicity to fish (Chronic toxicity)
(Oncorhynchus mykiss (rainbow trout)): > 100 mg/l End point: mortality Test Type: semi-static test Analytical monitoring: yes Method: OECD Test Guideline 215 GLP: yes
Toxicity to microorganisms
EC20 (activated sludge): > 927 mg/l Exposure time: 30 min Test Type: static test Method: DIN/EN ISO 8192 The value is given in analogy to the following substances: dl-α-Tocopherolacetate
Ecotoxicology Assessment
Chronic aquatic toxicityThis product has no known ecotoxicological effects.
Persistence and degradability
Components:
3,7,11-Trimethyldodeca-1,6,10-trien-3-ol,mixed isomers:
Biodegradabilityaerobic Inoculum: activated sludge Concentration: 100 mg/l Result: Readily biodegradable. Biodegradation: 70 - 80 % Exposure time: 28 d Method: OECD Test Guideline 301 GLP: yes
DL-α-Tocopherol:
Biodegradabilityaerobic Inoculum: activated sludge Result: Not readily biodegradable. Biodegradation: 20 % Exposure time: 28 d Method: OECD Test Guideline 301F GLP: yes
Bioaccumulative potential
Components:
3,7,11-Trimethyldodeca-1,6,10-trien-3-ol,mixed isomers:
Partition coefficient: noctanol/waterlog Pow: 4.5 (24 °C) pH: 7 Method: Regulation (EC) No. 440/2008, Annex, A.8 Remarks: Potential bioaccumulation
DL-α-Tocopherol:
Partition coefficient: noctanol/waterlog Pow: > 6 Method: (calculated) Remarks: (External MSDS) Potential bioaccumulation
Mobility in soil
No data available
Other adverse effects
Components:
3,7,11-Trimethyldodeca-1,6,10-trien-3-ol,mixed isomers:
Additional ecological informationDischarge into the environment must be avoided.
DL-α-Tocopherol:
Additional ecological informationDischarge into the environment must be avoided.
Disposal methods
Waste from residuesOffer surplus and non-recyclable solutions to a licensed disposal company.
International Regulations
IATA-DGR
UN/ID No. : UN 3082
Proper shipping name : Environmentally hazardous substance, liquid, n.o.s.
(3,7,11-Trimethyldodeca-1,6,10-trien-3-ol,mixed isomers)
Class : 9
Packing group : III
Labels : Class 9 - Miscellaneous dangerous substances and articles
Packing instruction (cargo aircraft) : 964
Packing instruction (passenger aircraft) : 964
Proper shipping name : Environmentally hazardous substance, liquid, n.o.s.
(3,7,11-Trimethyldodeca-1,6,10-trien-3-ol,mixed isomers)
Class : 9
Packing group : III
Labels : Class 9 - Miscellaneous dangerous substances and articles
Packing instruction (cargo aircraft) : 964
Packing instruction (passenger aircraft) : 964
IMDG-Code
UN number : UN 3082
Proper shipping name : ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S.
(3,7,11-Trimethyldodeca-1,6,10-trien-3-ol,mixed isomers)
Class : 9
Packing group : III
Labels : 9
EmS Code : F-A, S-F
Marine pollutant : yes
Proper shipping name : ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S.
(3,7,11-Trimethyldodeca-1,6,10-trien-3-ol,mixed isomers)
Class : 9
Packing group : III
Labels : 9
EmS Code : F-A, S-F
Marine pollutant : yes
Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code
Not applicable for product as supplied.
National Regulations
JT/T 617
UN number : UN 3082
Proper shipping name : ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S.
(3,7,11-Trimethyldodeca-1,6,10-trien-3-ol,mixed isomers)
Class : 9
Packing group : III
Labels : 9
Environmentally hazardous : no
Proper shipping name : ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S.
(3,7,11-Trimethyldodeca-1,6,10-trien-3-ol,mixed isomers)
Class : 9
Packing group : III
Labels : 9
Environmentally hazardous : no
Special precautions for user
Remarks : EHS-Mark required (ADR 2.2.9.1.10, IMDG code 2.10.3) for single packagings and combination packagings containing inner packagings with Dangerous
Goods > 5L for liquids or > 5kg for solids.
Packages smaller than or equal to 5 kg / L , not dangerous goods of Class 9
The transport classification(s) provided herein are for informational purposes only, and solely based upon the properties of the unpackaged material as it is described within this Safety Data Sheet. Transportation classifications may vary by mode of transportation, package sizes, and variations in regional or country regulations.
Goods > 5L for liquids or > 5kg for solids.
Packages smaller than or equal to 5 kg / L , not dangerous goods of Class 9
The transport classification(s) provided herein are for informational purposes only, and solely based upon the properties of the unpackaged material as it is described within this Safety Data Sheet. Transportation classifications may vary by mode of transportation, package sizes, and variations in regional or country regulations.
Catalogue of Hazardous Chemicals : This product is not listed in the catalogue of hazardous chemicals, but it meets the definition of hazardous chemicals and its principles of determination.
National regulatory information
Regulations on Safety Management of Hazardous Chemicals
Identification of Major Hazard Installations for Hazardous Chemicals (GB 18218)
Not listed
Hazardous Chemicals for Priority Management
Not listed under SAWS
China. List of Explosive Precursors
Not applicable
Regulations on Labour Protection in Workplaces where Toxic Substances are Used
Catalogue of Highly Toxic Chemicals
Not listed
Regulation of Environmental Management on the First Import of Chemicals and the Import and Export of Toxic Chemicals
China Severely Restricted Toxic Chemicals for Import and Export
Not listed
Full text of other abbreviations
AIIC - Australian Inventory of Industrial Chemicals
ANTT - National Agency forTransport by Land of Brazil
ASTM - American Society for the Testing of Materials
bw - Body weight
CMR - Carcinogen, Mutagen or Reproductive Toxicant
DIN -Standard of the German Institute for Standardisation
DSL - Domestic SubstancesList (Canada)
ECx - Concentration associated with x% response
ELx - Loading rate associated with x% response
EmS - Emergency Schedule
ENCS - Existing and NewChemical Substances (Japan)
ErCx - Concentration associated with x% growth rate response
ERG - Emergency Response Guide
GHS - Globally Harmonised System
GLP - Good Laboratory Practice
IARC - International Agency for Research on Can- cer
IATA - International Air Transport Association
IBC - International Code for theConstruction and Equipment of Ships carrying Dangerous Chemicals in Bulk
IC50 -Half maximal inhibitory concentration
ICAO - International Civil Aviation Organiza- tion
IECSC - Inventory of Existing Chemical Substances in China
IMDG - Interna- tional Maritime Dangerous Goods
IMO - International Maritime Organisation
ISHL -Industrial Safety and Health Law (Japan)
ISO - International Organisation forStandardisation
KECI - Korea Existing Chemicals Inventory
LC50 - Lethal Concen- tration to 50 % of a test population
LD50 - Lethal Dose to 50% of a test population (Median Lethal Dose)
MARPOL - International Convention for the Prevention of Pol- lution from Ships
MERCOSUR - The Agreement for the Facilitation of the Transport of Dangerous Goods
n.o.s. - Not Otherwise Specified
Nch - Chilean Norm
NO(A)EC - No Observed (Adverse) Effect Concentration
NO(A)EL - No Observed (Adverse) Ef- fect Level
NOELR - No Observable Effect Loading Rate
NOM - Official MexicanNorm
NTP - National Toxicology Program
NZIoC - New Zealand Inventory of Chem- icals
OECD - Organisation for Economic Co-operation and Development
OPPTS - Of- fice of Chemical Safety and Pollution Prevention
PBT - Persistent, Bioaccumulative and Toxic substance
PICCS - Philippines Inventory of Chemicals and Chemical Sub- stances
(Q)SAR - (Quantitative) Structure Activity Relationship
REACH - Regulation (EC) No 1907/2006 of the European Parliament and of the Council concerning theRegistration, Evaluation, Authorisation and Restriction of Chemicals
SADT - Self-Accelerating Decomposition Temperature
SDS - Safety Data Sheet
TCSI - TaiwanChemical Substance Inventory
TDG - Transportation of Dangerous Goods
TECI -Thailand Existing Chemicals Inventory
TSCA - Toxic Substances Control Act (UnitedStates)
UN - United Nations
UNRTDG - United Nations Recommendations on theTransport of Dangerous Goods
vPvB - Very Persistent and Very Bioaccumulative
WHMIS - Workplace Hazardous Materials Information System
ANTT - National Agency forTransport by Land of Brazil
ASTM - American Society for the Testing of Materials
bw - Body weight
CMR - Carcinogen, Mutagen or Reproductive Toxicant
DIN -Standard of the German Institute for Standardisation
DSL - Domestic SubstancesList (Canada)
ECx - Concentration associated with x% response
ELx - Loading rate associated with x% response
EmS - Emergency Schedule
ENCS - Existing and NewChemical Substances (Japan)
ErCx - Concentration associated with x% growth rate response
ERG - Emergency Response Guide
GHS - Globally Harmonised System
GLP - Good Laboratory Practice
IARC - International Agency for Research on Can- cer
IATA - International Air Transport Association
IBC - International Code for theConstruction and Equipment of Ships carrying Dangerous Chemicals in Bulk
IC50 -Half maximal inhibitory concentration
ICAO - International Civil Aviation Organiza- tion
IECSC - Inventory of Existing Chemical Substances in China
IMDG - Interna- tional Maritime Dangerous Goods
IMO - International Maritime Organisation
ISHL -Industrial Safety and Health Law (Japan)
ISO - International Organisation forStandardisation
KECI - Korea Existing Chemicals Inventory
LC50 - Lethal Concen- tration to 50 % of a test population
LD50 - Lethal Dose to 50% of a test population (Median Lethal Dose)
MARPOL - International Convention for the Prevention of Pol- lution from Ships
MERCOSUR - The Agreement for the Facilitation of the Transport of Dangerous Goods
n.o.s. - Not Otherwise Specified
Nch - Chilean Norm
NO(A)EC - No Observed (Adverse) Effect Concentration
NO(A)EL - No Observed (Adverse) Ef- fect Level
NOELR - No Observable Effect Loading Rate
NOM - Official MexicanNorm
NTP - National Toxicology Program
NZIoC - New Zealand Inventory of Chem- icals
OECD - Organisation for Economic Co-operation and Development
OPPTS - Of- fice of Chemical Safety and Pollution Prevention
PBT - Persistent, Bioaccumulative and Toxic substance
PICCS - Philippines Inventory of Chemicals and Chemical Sub- stances
(Q)SAR - (Quantitative) Structure Activity Relationship
REACH - Regulation (EC) No 1907/2006 of the European Parliament and of the Council concerning theRegistration, Evaluation, Authorisation and Restriction of Chemicals
SADT - Self-Accelerating Decomposition Temperature
SDS - Safety Data Sheet
TCSI - TaiwanChemical Substance Inventory
TDG - Transportation of Dangerous Goods
TECI -Thailand Existing Chemicals Inventory
TSCA - Toxic Substances Control Act (UnitedStates)
UN - United Nations
UNRTDG - United Nations Recommendations on theTransport of Dangerous Goods
vPvB - Very Persistent and Very Bioaccumulative
WHMIS - Workplace Hazardous Materials Information System
Disclaimer:
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.