Chemical Safety Data Sheet MSDS / SDS
NICKEL(II) HYDROXIDE
Revision Date:2026-04-25Revision Number:1
Product identifier
- Product name: NICKEL(II) HYDROXIDE
- CBnumber: CB2411181
- CAS: 12054-48-7
- EINECS Number: 235-008-5
- Synonyms: Nickel Hydroxide,Ni(OH)2
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 010-86108875
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
P308+P313 IF exposed or concerned: Get medical advice/attention.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P273 Avoid release to the environment.
P202 Do not handle until all safety precautions have been read and understood.
Hazard statements
H410 Very toxic to aquatic life with long lasting effects
H372 Causes damage to organs through prolonged or repeated exposure
H341 Suspected of causing genetic defects
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled
H317 May cause an allergic skin reaction
H315 Causes skin irritation
Substance
- Product name: NICKEL(II) HYDROXIDE
- Synonyms: Nickel Hydroxide,Ni(OH)2
- CAS: 12054-48-7
- EC number: 235-008-5
- MF: H2NiO2
- MW: 92.71
4.1 Description of first-aid measures
General adviceFirst aiders need to protect themselves. Show this material safety data sheet to the doctor in attendance.
If inhaled
After inhalation: fresh air. Immediately call in physician. If breathing stops: immediately apply artificial respiration, if necessary also oxygen.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. Consult a physician.
In case of eye contact
After eye contact: rinse out with plenty of water. Call in ophthalmologist. Remove contact lenses.
If swallowed
After swallowing: immediately make victim drink water (two glasses at most). Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available
4.4 Notes to physician
No data available
5.1 Extinguishing media
Suitable extinguishing mediaUse extinguishing measures that are appropriate to local circumstances and the surrounding environment.
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.
5.2 Special hazards arising from the substance or mixture
Nickel/nickel oxides
Not combustible.
Ambient fire may liberate hazardous vapours.
Not combustible.
Ambient fire may liberate hazardous vapours.
5.3 Advice for firefighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.
Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.
NFPA 704
3
0
0
| HEALTH | 3 | Short exposure could cause serious temporary or moderate residual injury (e.g. liquid hydrogen, sulfuric acid, calcium hypochlorite, hexafluorosilicic acid) | |
| FIRE | 0 | Materials that will not burn under typical fire conditions, including intrinsically noncombustible materials such as concrete, stone, and sand. Materials that will not burn in air when exposed to a temperature of 820 °C (1,500 °F) for a period of 5 minutes.(e.g. Carbon tetrachloride) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
6.1 Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Avoid generation and inhalation of dusts in all circumstances. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert.
For personal protection see section 8.
For personal protection see section 8.
6.2 Environmental precautions
Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up carefully. Dispose of properly. Clean up affected area.
Avoid generation of dusts.
Avoid generation of dusts.
6.4 Reference to other sections
For disposal see section 13.
7.1 Precautions for safe handling
Advice on safe handlingWork under hood. Do not inhale substance/mixture.
Hygiene measures
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
For precautions see section 2.2.
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Storage conditionsTightly closed. Dry. Keep in a well-ventilated place. Keep locked up or in an area accessible only to qualified or authorized persons.
Storage class
Storage class (TRGS 510): 6.1D: Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
8.1 Control parameters
Ingredients with workplace control parameters| ['Component', 'CAS-No.', 'Value', 'Control\nparameters', 'Basis'] | ['Nickel dihydroxide', '12054-48-\n7', 'PC-TWA', '1 mg/m3', 'Occupational exposure limits for\nhazardous agents in the\nworkplace - Chemical\nhazardous agents.'] | ['', 'Remarks', 'G1 - Carcinogenic to humans', None, None] |
|---|
| ['Component', 'CAS-No.', 'Parameters', 'Value', 'Biological\nspecimen', 'Basis'] | ['Nickel\ndihydroxide', '12054-48-\n7', 'Nickel', '5 µg/l', 'Urine', 'ACGIH -\nBiological\nExposure Indices\n(BEI)'] | ['', 'Remarks', 'End of shift at end of workweek', None, None, None] | ['', '', 'Nickel', '30 µg/l', 'Urine', 'ACGIH -\nBiological\nExposure Indices\n(BEI)'] | ['', '', 'End of shift at end of workweek', None, None, None] |
|---|
8.2 Exposure controls
Appropriate engineering controlsImmediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
Personal protective equipment
Eye/face protection
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses
Skin protection
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN 16523-1 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell,
Internet: www.kcl.de).
Full contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:KCL 741 L
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:KCL 741 L
Body Protection
Internet: www.kcl.de).
Full contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:KCL 741 L
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:KCL 741 L
protective clothing
Respiratory protection
required when dusts are generated.
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Control of environmental exposure
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Do not let product enter drains.
Information on basic physicochemical properties
- a) Physical statepowder
- b) Colorlight green
- c) OdorNo data available
- d) Melting point/freezing pointMelting point: 230 °C
- e) Initial boiling point and boiling rangeNo data available
- f) Flammability (solid, gas)The product is not flammable. - Flammability (solids)
- g) Upper/lower flammability or explosive limitsNo data available
- h) Flash pointNot applicable
- i) Autoignition temperature> 400 °C - Relative self-ignition temperature for solidsdoes not ignite
- j) Decomposition temperature200 °C
- k) pH8.37(1 mM solution);8.37(10 mM solution);8.37(100 mM solution)
- l) ViscosityViscosity, kinematic: No data available
Viscosity, dynamic: No data available - m) Water solubility0.1 g/l at 20 °C - OECD Test Guideline 105- insoluble
- n) Partition coefficient n-octanol/waterNot applicable for inorganic substances
- o) Vapor pressureNo data available
- p) Density4.1 g/cm3
- Relative density3.8 at 21 °C - OECD Test Guideline 109
- r) Particle characteristicsNo data available
- s) Explosive propertiesNo data available
- t) Oxidizing propertiesnone
- Solubilitywater: soluble
9.2 Other safety information
No data available
10.1 Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
10.2 Possibility of hazardous reactions
Violent reactions possible with:
Strong acids
Strong acids
10.3 Conditions to avoid
no information available
10.4 Incompatible materials
No data available
10.5 Hazardous decomposition products
In the event of fire: see section 5
11.1 Information on toxicological effects
Acute toxicityLD50 Oral - Rat - male and female - 1,540 mg/kg (OECD Test Guideline 401)
LC50 Inhalation - Rat - 4 h - 1.2 mg/l - dust/mist
Remarks: Behavioral:Excitement.
Lungs, Thorax, or Respiration:Dyspnea.
Skin and Appendages: Other: Hair.
(RTECS)
LD50 Dermal - Rat - > 2,000 mg/kg
Remarks: (RTECS)
Skin corrosion/irritation
LC50 Inhalation - Rat - 4 h - 1.2 mg/l - dust/mist
Remarks: Behavioral:Excitement.
Lungs, Thorax, or Respiration:Dyspnea.
Skin and Appendages: Other: Hair.
(RTECS)
LD50 Dermal - Rat - > 2,000 mg/kg
Remarks: (RTECS)
Skin - Rabbit
Result: Irritating to skin. - 4 h (OECD Test Guideline 404)
Serious eye damage/eye irritation
Result: Irritating to skin. - 4 h (OECD Test Guideline 404)
Eyes - Rabbit
Result: Mild eye irritation (OECD Test Guideline 405)
Respiratory or skin sensitization
Result: Mild eye irritation (OECD Test Guideline 405)
May cause allergic skin reaction. Classified according to Regulation (EU) 1272/2008, Annex
VI (Table 3.1/3.2)
May cause allergy or asthma symptoms or breathing difficulties if inhaled. Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Germ cell mutagenicity
VI (Table 3.1/3.2)
May cause allergy or asthma symptoms or breathing difficulties if inhaled. Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Suspected of causing genetic defects.
Test Type: In vitro mammalian cell gene mutation test
Test system: mouse lymphoma cells
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 476
Result: positive
Test Type: In vitro mammalian cell gene mutation test
Test system: Chinese hamster ovary cells
Metabolic activation: without metabolic activation
Method: OECD Test Guideline 476
Result: positive
Carcinogenicity
Test Type: In vitro mammalian cell gene mutation test
Test system: mouse lymphoma cells
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 476
Result: positive
Test Type: In vitro mammalian cell gene mutation test
Test system: Chinese hamster ovary cells
Metabolic activation: without metabolic activation
Method: OECD Test Guideline 476
Result: positive
Positive evidence from human epidemiological studies (inhalation)
Reproductive toxicity
May damage the unborn child.
Specific target organ toxicity - single exposure
Classified based on available data. For more details, see section 2
Specific target organ toxicity - repeated exposure
Inhalation - Causes damage to organs through prolonged or repeated exposure.
- Lungs
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Aspiration hazard
- Lungs
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Classified based on available data. For more details, see section 2
11.2 Additional Information
RTECS: QR7040000
Material is extremely destructive to tissue of the mucous membranes and upper respiratory tract, eyes, and skin., Cough, Shortness of breath, Headache, Nausea
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
Material is extremely destructive to tissue of the mucous membranes and upper respiratory tract, eyes, and skin., Cough, Shortness of breath, Headache, Nausea
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
12.1 Toxicity
Toxicity to fish semi-static test LC50 - Oncorhynchus mykiss (rainbow trout) - 15.3 mg/l - 96 h
Remarks: (ECHA)
Toxicity to daphnia static test LC50 - Ceriodaphnia dubia (water flea) - 0.074 mg/l - 48 and other aquatic h invertebrates (US-EPA)
Toxicity to algae static test ErC50 - Pseudokirchneriella subcapitata - 0.081 - 0.148 mg/l - 72 h (OECD Test Guideline 201)
Toxicity to bacteria EC50 - activated sludge - 33 mg/l - 30 min (ISO 8192)
Toxicity to flow-through test NOEC - Oncorhynchus mykiss (rainbow trout) - fish(Chronic toxicity) 0.062 mg/l - 32 d
Remarks: (ECHA)
Toxicity to daphnia semi-static test NOEC - Ceriodaphnia dubia (water flea) - 0.005 - and other aquatic 0.015 mg/l - 7 d invertebrates(Chronic (US-EPA) toxicity)
Remarks: (ECHA)
Toxicity to daphnia static test LC50 - Ceriodaphnia dubia (water flea) - 0.074 mg/l - 48 and other aquatic h invertebrates (US-EPA)
Toxicity to algae static test ErC50 - Pseudokirchneriella subcapitata - 0.081 - 0.148 mg/l - 72 h (OECD Test Guideline 201)
Toxicity to bacteria EC50 - activated sludge - 33 mg/l - 30 min (ISO 8192)
Toxicity to flow-through test NOEC - Oncorhynchus mykiss (rainbow trout) - fish(Chronic toxicity) 0.062 mg/l - 32 d
Remarks: (ECHA)
Toxicity to daphnia semi-static test NOEC - Ceriodaphnia dubia (water flea) - 0.005 - and other aquatic 0.015 mg/l - 7 d invertebrates(Chronic (US-EPA) toxicity)
12.2 Persistence and degradability
The methods for determining biodegradability are not applicable to inorganic substances.
12.3 Bioaccumulative potential
No data available
12.4 Mobility in soil
No data available
12.5 Results of PBT and vPvB assessment
PBT/vPvB assessment not available as chemical safety assessment not required/not conducted
12.6 Endocrine disrupting properties
No data available
12.7 Other adverse effects
No data available
13.1 Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company.
Offer surplus and non-recyclable solutions to a licensed disposal company.
14.1 UN number
ADR/RID: 3077
IMDG: 3077
IATA-DGR: 3077
IMDG: 3077
IATA-DGR: 3077
14.2 UN proper shipping name
ADR/RID: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (Nickel dihydroxide)
IMDG: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (Nickel dihydroxide)
IATA-DGR: Environmentally hazardous substance, solid, n.o.s. (Nickel dihydroxide)
IMDG: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (Nickel dihydroxide)
IATA-DGR: Environmentally hazardous substance, solid, n.o.s. (Nickel dihydroxide)
14.3 Transport hazard class(es)
ADR/RID: 9
IMDG: 9
IATA-DGR: 9
IMDG: 9
IATA-DGR: 9
14.4 Packaging group
ADR/RID: III
IMDG: III
IATA-DGR: III
IMDG: III
IATA-DGR: III
14.5 Environmental hazards
ADR/RID: yes
IMDG Marine pollutant: yes
IATA-DGR: yes
IMDG Marine pollutant: yes
IATA-DGR: yes
14.6 Special precautions for user
14.7 Incompatible materials
Further information: EHS-Mark required (ADR 2.2.9.1.10, IMDG code 2.10.3) for single packagings and combination packagings containing inner packagings with Dangerous Goods > 5L for liquids or > 5kg for solids.
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
National regulatory information
Law on the Prevention and Control of Occupational Diseases
Regulations on Occupational Labor Protection in the at workplaces where Toxic
Substances Are Used
Catalogue of Highly Toxic Chemicals : Listed
Other regulations
Please pay attention on the waste treatment should also comply with local regulations requirement.
Law on the Prevention and Control of Occupational Diseases
Regulations on Occupational Labor Protection in the at workplaces where Toxic
Substances Are Used
Catalogue of Highly Toxic Chemicals : Listed
Other regulations
Please pay attention on the waste treatment should also comply with local regulations requirement.
Abbreviations and acronyms
CAS: Chemical Abstracts Service
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
Disclaimer:
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.
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