Safety Data Sheet

Chemical Safety Data Sheet MSDS / SDS

Revision Date:2026-03-20Revision Number:1

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Relevant identified uses of the substance or mixture and uses advised against

Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
Uses advised against: none

Company Identification

Company: Chemicalbook
Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
Telephone: 010-86108875

SECTION 2: Hazards identification

GHS Label elements, including precautionary statements

Signal wordDanger

Precautionary statements

P501 Dispose of contents/container to..…

P391 Collect spillage. Hazardous to the aquatic environment

P273 Avoid release to the environment.

P501 Dispose of contents/container to..…

P391 Collect spillage. Hazardous to the aquatic environment

P273 Avoid release to the environment.

P501 Dispose of contents/container to..…

P330 Rinse mouth.

P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P270 Do not eat, drink or smoke when using this product.

P264 Wash skin thouroughly after handling.

P501 Dispose of contents/container to..…

P314 Get medical advice/attention if you feel unwell.

P270 Do not eat, drink or smoke when using this product.

P264 Wash skin thouroughly after handling.

P260 Do not breathe dust/fume/gas/mist/vapours/spray.

P501 Dispose of contents/container to..…

P363 Wash contaminated clothing before reuse.

P321 Specific treatment (see … on this label).

P333+P313 IF SKIN irritation or rash occurs: Get medical advice/attention.

P302+P352 IF ON SKIN: wash with plenty of soap and water.

P280 Wear protective gloves/protective clothing/eye protection/face protection.

P272 Contaminated work clothing should not be allowed out of the workplace.

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

P501 Dispose of contents/container to..…

P405 Store locked up.

P308+P313 IF exposed or concerned: Get medical advice/attention.

P281 Use personal protective equipment as required.

P202 Do not handle until all safety precautions have been read and understood.

P201 Obtain special instructions before use.

Hazard statements

H302 Harmful if swallowed

H361 Suspected of damaging fertility or the unborn child

H400 Very toxic to aquatic life

H410 Very toxic to aquatic life with long lasting effects

H372 Causes damage to organs through prolonged or repeated exposure

H317 May cause an allergic skin reaction

SECTION 3: Composition/information on ingredients

Substance

Product name: Osimertinib mesylate
Synonyms: Osimertinib;PB1211
CAS: 1421373-66-1
EC number: 200-064-1
MF: C29H37N7O5S
MW: 595.72

SECTION 4: First aid measures

SECTION 5: Firefighting measures

SECTION 6: Accidental release measures

SECTION 7: Handling and storage

SECTION 8: Exposure controls/personal protection

control parameter

Hazard composition and occupational exposure limits

Does not contain substances with occupational exposure limits.

SECTION 9: Physical and chemical properties

SECTION 10: Stability and reactivity

SECTION 11: Toxicological information

SECTION 12: Ecological information

SECTION 13: Disposal considerations

SECTION 14: Transport information

SECTION 15: Regulatory information

SECTION 16: Other information

Disclaimer:

The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.