Chemical Safety Data Sheet MSDS / SDS

Polymyxin B sulfate

Revision Date:2026-03-21Revision Number:1

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier

Product name: Polymyxin B sulfate
CBnumber: CB8666707
CAS: 1405-20-5
EINECS Number: 215-774-7
Synonyms: POLYMYXIN B;POLYMYXIN B SULPHATE

Relevant identified uses of the substance or mixture and uses advised against

Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
Uses advised against: none

Company Identification

Company: Chemicalbook
Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
Telephone: 010-86108875

SECTION 2: Hazards identification

GHS Label elements, including precautionary statements

Symbol(GHS)

Signal wordWarning

Precautionary statements

P264 Wash skin thouroughly after handling.

P270 Do not eat, drink or smoke when using this product.

P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501 Dispose of contents/container to..…

Hazard statements

H302 Harmful if swallowed

SECTION 3: Composition/information on ingredients

Substance

Product name: Polymyxin B sulfate
Synonyms: POLYMYXIN B;POLYMYXIN B SULPHATE
CAS: 1405-20-5
EC number: 215-774-7
MF: C56H100N16O17S
MW: 1301.56

SECTION 4: First aid measures

4.1 Description of first-aid measures

General advice

Show this material safety data sheet to the doctor in attendance.

If inhaled

After inhalation: fresh air.

In case of skin contact

In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower.

In case of eye contact

After eye contact: rinse out with plenty of water. Remove contact lenses.

If swallowed

After swallowing: immediately make victim drink water (two glasses at most). Consult a physician.

4.2 Most important symptoms and effects, both acute and delayed

The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11

4.3 Indication of any immediate medical attention and special treatment needed

No data available

4.4 Notes to physician

No data available

SECTION 5: Firefighting measures

5.1 Extinguishing media

Suitable extinguishing media

Water Foam Carbon dioxide (CO2) Dry powder

Unsuitable extinguishing media

For this substance/mixture no limitations of extinguishing agents are given.

5.2 Special hazards arising from the substance or mixture

Carbon oxides
Nitrogen oxides (NOx)
Sulfur oxides
Combustible.
Fire may cause evolution of:
Sulfur oxides
Development of hazardous combustion gases or vapours possible in the event of fire.

5.3 Advice for firefighters

In the event of fire, wear self-contained breathing apparatus.
Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.

NFPA 704

HEALTH	3	Short exposure could cause serious temporary or moderate residual injury (e.g. liquid hydrogen, sulfuric acid, calcium hypochlorite, hexafluorosilicic acid)
FIRE	0	Materials that will not burn under typical fire conditions, including intrinsically noncombustible materials such as concrete, stone, and sand. Materials that will not burn in air when exposed to a temperature of 820 °C (1,500 °F) for a period of 5 minutes.(e.g. Carbon tetrachloride)
REACT	0	Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2)
SPEC. HAZ.

SECTION 6: Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Advice for non-emergency personnel: Avoid inhalation of dusts. Avoid substance contact.
Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert.
For personal protection see section 8.

6.2 Environmental precautions

Do not let product enter drains.

6.3 Methods and materials for containment and cleaning up

Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up dry. Dispose of properly. Clean up affected area. Avoid generation of dusts.

6.4 Reference to other sections

For disposal see section 13.

SECTION 7: Handling and storage

7.1 Precautions for safe handling

For precautions see section 2.2.

7.2 Conditions for safe storage, including any incompatibilities

Storage conditions

Tightly closed. Dry.
Recommended storage temperature see product label.

Storage class

Storage class (TRGS 510): 11: Combustible Solids

SECTION 8: Exposure controls/personal protection

8.1 Control parameters

Ingredients with workplace control parameters

Contains no substances with occupational exposure limit values.

8.2 Exposure controls

Appropriate engineering controls

Change contaminated clothing. Preventive skin protection recommended. Wash hands after working with substance.

Personal protective equipment

Eye/face protection

Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses

Skin protection

This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN 16523-1 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell,
Internet: www.kcl.de).
Full contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:KCL 741 L
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:KCL 741 L

Body Protection

protective clothing

Respiratory protection

required when dusts are generated.
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.

Control of environmental exposure

Do not let product enter drains.

SECTION 9: Physical and chemical properties

Information on basic physicochemical properties

a) Physical statepowder
b) Colorcolorless or slightly yellow
c) OdorNo data available
d) Melting point/freezing pointNo data available
e) Initial boiling point and boiling rangeNo data available
f) Flammability (solid, gas)No data available
g) Upper/lower flammability or explosive limitsNo data available
h) Flash pointNot applicable
i) Autoignition temperatureNo data available
j) Decomposition temperatureNo data available
k) pHpH (10g/L, 25℃) : 4.5～7.0
l) ViscosityViscosity, kinematic: No data available
Viscosity, dynamic: No data available
m) Water solubilitySoluble in water at 50mg/ml/n
n) Partition coefficient n-octanol/waterNo data available
o) Vapor pressureNo data available
p) DensityNo data available
Relative densityNo data available
q) Relative vapor densityNo data available
r) Particle characteristicsNo data available
s) Explosive propertiesNo data available
t) Oxidizing propertiesnone
SolubilityH₂O: 50 mg/mL

9.2 Other safety information

No data available

SECTION 10: Stability and reactivity

10.1 Chemical stability

The product is chemically stable under standard ambient conditions (room temperature) .

10.2 Possibility of hazardous reactions

Violent reactions possible with: strong oxidising agents

10.3 Conditions to avoid

no information available

10.4 Incompatible materials

No data available

10.5 Hazardous decomposition products

In the event of fire: see section 5

SECTION 11: Toxicological information

11.1 Information on toxicological effects

Acute toxicity

LD50 Oral - Mouse - 790 mg/kg
Inhalation: No data available
Dermal: No data available

Skin corrosion/irritation

Remarks: No data available

Serious eye damage/eye irritation