11.1 Information on toxicological effects
Acute toxicity
LD50 Oral - Rat - female - 3.020 mg/kg
Remarks: (ECHA)
Inhalation: No data available
Dermal: No data available
Skin corrosion/irritation
Classified based on available data. For more details, see section 2
Serious eye damage/eye irritation
Remarks: No data available
Respiratory or skin sensitization
Classified based on available data. For more details, see section 2
Germ cell mutagenicity
Test Type: Ames test
Test system: Salmonella typhimurium
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 471
Result: negative
Remarks: (ECHA)
Test Type: In vitro mammalian cell gene mutation test
Test system: mouse lymphoma cells
Metabolic activation: without metabolic activation
Method: OECD Test Guideline 476
Result: negative
Remarks: (ECHA)
Test Type: Mutagenicity (mammal cell test): chromosome aberration.
Test system: Chinese hamster lung cells
Metabolic activation: without metabolic activation
Method: OECD Test Guideline 473
Result: positive
Remarks: (ECHA)
Carcinogenicity
Classified based on available data. For more details, see section 2
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Classified based on available data. For more details, see section 2
Specific target organ toxicity - repeated exposure
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2
11.2 Additional Information
Endocrine disrupting properties
Product:
Assessment : The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.
Repeated dose toxicity - Rat - male - Oral - 2 yr - NOAEL (No observed adverse effect level) - 1.820 mg/kg - LOAEL (Lowest observed adverse effect level) - 110 mg/kg
Remarks: (ECHA)
RTECS: TS8050000 hyperkalemia, Nausea, Vomiting, Abdominal pain, Diarrhea, Constipation., Paresthesia.,
Thirst, Dizziness, Rash, pruritus, Weakness, muscle cramps, minor psychiatric changes, minor visual changes
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.