Chemical Safety Data Sheet MSDS / SDS
Propionaldehyde
Revision Date:2026-03-21Revision Number:1
Product identifier
- Product name: Propionaldehyde
- CBnumber: CB4852968
- CAS: 123-38-6
- EINECS Number: 204-623-0
- Synonyms: PROPANAL;Propanaldehyde
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 010-86108875
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
Hazard statements
H335 May cause respiratory irritation
H318 Causes serious eye damage
H315 Causes skin irritation
H225 Highly Flammable liquid and vapour
Substance
- Product name: Propionaldehyde
- Synonyms: PROPANAL;Propanaldehyde
- CAS: 123-38-6
- EC number: 204-623-0
- MF: C3H6O
- MW: 58.08
4.1 Description of first-aid measures
General adviceShow this material safety data sheet to the doctor in attendance.
If inhaled
After inhalation: fresh air.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower.
In case of eye contact
After eye contact: rinse out with plenty of water. Immediately call in ophthalmologist.
Remove contact lenses.
If swallowed
Remove contact lenses.
After swallowing: immediately make victim drink water (two glasses at most). Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available
4.4 Notes to physician
No data available
5.1 Extinguishing media
Suitable extinguishing mediaWater Foam Carbon dioxide (CO2) Dry powder
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.
5.2 Special hazards arising from the substance or mixture
Carbon oxides
Combustible.
Pay attention to flashback.
Vapors are heavier than air and may spread along floors.
Development of hazardous combustion gases or vapours possible in the event of fire.
Forms explosive mixtures with air at ambient temperatures.
Combustible.
Pay attention to flashback.
Vapors are heavier than air and may spread along floors.
Development of hazardous combustion gases or vapours possible in the event of fire.
Forms explosive mixtures with air at ambient temperatures.
5.3 Advice for firefighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
Remove container from danger zone and cool with water. Prevent fire extinguishing water from contaminating surface water or the ground water system.
Remove container from danger zone and cool with water. Prevent fire extinguishing water from contaminating surface water or the ground water system.
NFPA 704
2
3
2
| HEALTH | 2 | Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury (e.g. diethyl ether, ammonium phosphate, iodine) | |
| FIRE | 3 | Liquids and solids (including finely divided suspended solids) that can be ignited under almost all ambient temperature conditions . Liquids having a flash point below 22.8 °C (73 °F) and having a boiling point at or above 37.8 °C (100 °F) or having a flash point between 22.8 and 37.8 °C (73 and 100 °F). (e.g. gasoline, acetone) | |
| REACT | 2 | Undergoes violent chemical change at elevated temperatures and pressures, reacts violently with water, or may form explosive mixtures with water (e.g. white phosphorus, potassium, sodium) | |
| SPEC. HAZ. |
6.1 Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Keep away from heat and sources of ignition.
Evacuate the danger area, observe emergency procedures, consult an expert.
For personal protection see section 8.
Evacuate the danger area, observe emergency procedures, consult an expert.
For personal protection see section 8.
6.2 Environmental precautions
Do not let product enter drains. Risk of explosion.
6.3 Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up with liquid-absorbent material (e.g. Chemizorb® ).
Dispose of properly. Clean up affected area.
Dispose of properly. Clean up affected area.
6.4 Reference to other sections
For disposal see section 13.
7.1 Precautions for safe handling
Advice on safe handlingWork under hood. Do not inhale substance/mixture. Avoid generation of vapours/aerosols.
Advice on protection against fire and explosion
Keep away from open flames, hot surfaces and sources of ignition.Take precautionary measures against static discharge.
Hygiene measures
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
For precautions see section 2.2.
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Storage conditionsKeep container tightly closed in a dry and well-ventilated place. Keep away from heat and sources of ignition.
Storage stabilityRecommended storage temperature
2 - 8 °C
Handle and open container with care. Handle and store under inert gas. Air and moisture sensitive.
Storage class
Handle and open container with care. Handle and store under inert gas. Air and moisture sensitive.
Storage class (TRGS 510): 3: Flammable liquids
8.1 Control parameters
Ingredients with workplace control parameters| ['Component', 'CAS-No.', 'Value', 'Control', 'Basis'] |
|---|
8.2 Exposure controls
Appropriate engineering controlsImmediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
Personal protective equipment
Eye/face protection
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Tightly fitting safety goggles
Skin protection
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN 16523-1 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell,
Internet: www.kcl.de).
Splash contact
Material: butyl-rubber
Minimum layer thickness: 0.7 mm
Break through time: 240 min
Material tested:Butoject® (KCL 898)
Internet: www.kcl.de).
Splash contact
Material: butyl-rubber
Minimum layer thickness: 0.7 mm
Break through time: 240 min
Material tested:Butoject® (KCL 898)
Body Protection
Flame retardant antistatic protective clothing.
Respiratory protection
required when vapours/aerosols are generated. Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Control of environmental exposure
Do not let product enter drains. Risk of explosion.
Information on basic physicochemical properties
- a) Physical stateclear, liquid
- b) Colorcolorless
- c) OdorStench.
- d) Melting point/freezing pointMelting point/range: -81 °C
- e) Initial boiling point and boiling range47.6 °C at 1,003.27 hPa
- f) Flammability (solid, gas)No data available
- g) Upper/lower flammability or explosive limitsUpper explosion limit: 16.1 %(V)
Lower explosion limit: 2.6 %(V) - h) Flash point-30 °C - closed cup
- i) Autoignition temperature195 °C at 1,013.25 hPa - DIN 51794
- j) Decomposition temperatureNo data available
- k) pHNo data available
- l) ViscosityViscosity, kinematic: No data available
Viscosity, dynamic: 0.317 mPa.s at 26.7 °C 0.375 mPa.s at 20 °C - m) Water solubility306 g/l at 25 °C completely soluble
- n) Partition coefficient n-octanol/waterlog Pow: 0.59 at 25 °C - Bioaccumulation is not expected.
- o) Vapor pressure400.46 hPa at 23.61 °C
- p) Density0.80 g/cm3 at 20 °C
- Relative density0.805 g/mL at 25 °C (lit.)
- q) Relative vapor density2 (vs air)
- r) Particle characteristicsNo data available
- s) Explosive propertiesNo data available
- t) Oxidizing propertiesnone
- Solubilitysoluble in chloroform; miscible with alcohol and ether
- Dielectric constant18.9（17℃）
9.2 Other safety information
Surface tension23.4 mN/m at 20 °C
Relative vapor density
2.01 - (Air = 1.0)
10.1 Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
10.2 Possibility of hazardous reactions
Exothermic reaction with: alkali hydroxides mineral acids
Oxidizing agents
Oxidizing agents
10.3 Conditions to avoid
Warming.
10.4 Incompatible materials
No data available
10.5 Hazardous decomposition products
In the event of fire: see section 5
11.1 Information on toxicological effects
Acute toxicityLD50 Oral - Rat - female - 1,690 mg/kg (OECD Test Guideline 401)
LC50 Inhalation - Mouse - 4 h - 10.9 mg/l - vapor
Remarks: Lungs, Thorax, or Respiration:Acute pulmonary edema.
Liver:Other changes.
Kidney, Ureter, Bladder:Other changes.
(RTECS)
LD50 Dermal - Rabbit - female - 2,460 mg/kg (OECD Test Guideline 402)
Remarks: Behavioral:Somnolence (general depressed activity).
Behavioral:Convulsions or effect on seizure threshold.
Lungs, Thorax, or Respiration:Dyspnea.
Skin corrosion/irritation
LC50 Inhalation - Mouse - 4 h - 10.9 mg/l - vapor
Remarks: Lungs, Thorax, or Respiration:Acute pulmonary edema.
Liver:Other changes.
Kidney, Ureter, Bladder:Other changes.
(RTECS)
LD50 Dermal - Rabbit - female - 2,460 mg/kg (OECD Test Guideline 402)
Remarks: Behavioral:Somnolence (general depressed activity).
Behavioral:Convulsions or effect on seizure threshold.
Lungs, Thorax, or Respiration:Dyspnea.
Skin - Rabbit
Result: Skin irritation - 4 h (OECD Test Guideline 404)
Serious eye damage/eye irritation
Result: Skin irritation - 4 h (OECD Test Guideline 404)
Eyes - Rabbit
Result: Risk of serious damage to eyes.
(OECD Test Guideline 405)
Respiratory or skin sensitization
Result: Risk of serious damage to eyes.
(OECD Test Guideline 405)
Local lymph node assay (LLNA) - Mouse
Result: negative (OECD Test Guideline 429)
Germ cell mutagenicity
Result: negative (OECD Test Guideline 429)
Test Type: Ames test
Test system: S. typhimurium
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 471
Result: negative
Test Type: Micronucleus test
Species: Mouse
Cell type: Red blood cells (erythrocytes)
Application Route: Intraperitoneal
Method: OECD Test Guideline 474
Result: negative
Carcinogenicity
Test system: S. typhimurium
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 471
Result: negative
Test Type: Micronucleus test
Species: Mouse
Cell type: Red blood cells (erythrocytes)
Application Route: Intraperitoneal
Method: OECD Test Guideline 474
Result: negative
Classified based on available data. For more details, see section 2
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Inhalation - May cause respiratory irritation. - Respiratory system
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Specific target organ toxicity - repeated exposure
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2
11.2 Additional Information
RTECS: UE0350000
Material is extremely destructive to tissue of the mucous membranes and upper respiratory tract, eyes, and skin., Cough, Shortness of breath, Headache, Nausea
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
After absorption:
Tiredness narcosis
Other dangerous properties can not be excluded.
Handle in accordance with good industrial hygiene and safety practice.
Material is extremely destructive to tissue of the mucous membranes and upper respiratory tract, eyes, and skin., Cough, Shortness of breath, Headache, Nausea
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
After absorption:
Tiredness narcosis
Other dangerous properties can not be excluded.
Handle in accordance with good industrial hygiene and safety practice.
12.1 Toxicity
Toxicity to fish static test LC50 - Pimephales promelas (fathead minnow) - 14 mg/l - 96 h
Remarks: (ECHA)
Toxicity to daphnia static test EC50 - Daphnia magna (Water flea) - 88.7 mg/l - 48 h and other aquatic (Regulation (EC) No. 440/2008, Annex, C.2) invertebrates
Toxicity to algae static test ErC50 - Desmodesmus subspicatus (green algae) - 260 mg/l - 72 h (DIN 38412)
12.2 Persistence and degradability
Remarks: (ECHA)
Toxicity to daphnia static test EC50 - Daphnia magna (Water flea) - 88.7 mg/l - 48 h and other aquatic (Regulation (EC) No. 440/2008, Annex, C.2) invertebrates
Toxicity to algae static test ErC50 - Desmodesmus subspicatus (green algae) - 260 mg/l - 72 h (DIN 38412)
Biodegradability aerobic - Exposure time 28 d
Result: ca.91 - 97 % - Readily biodegradable.
(OECD Test Guideline 301C)
Ratio BOD/ThBOD 95 %
Ratio BOD/ThBOD 38 %
Result: ca.91 - 97 % - Readily biodegradable.
(OECD Test Guideline 301C)
Ratio BOD/ThBOD 95 %
Ratio BOD/ThBOD 38 %
12.3 Bioaccumulative potential
No data available
12.4 Mobility in soil
No data available
12.5 Results of PBT and vPvB assessment
PBT/vPvB assessment not available as chemical safety assessment not required/not conducted
12.6 Endocrine disrupting properties
No data available
12.7 Other adverse effects
Discharge into the environment must be avoided.
13.1 Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company.
Offer surplus and non-recyclable solutions to a licensed disposal company.
14.1 UN number
ADR/RID: 1275
IMDG: 1275
IATA-DGR: 1275
IMDG: 1275
IATA-DGR: 1275
14.2 UN proper shipping name
ADR/RID: PROPIONALDEHYDE
IMDG: PROPIONALDEHYDE
IATA-DGR: Propionaldehyde
IMDG: PROPIONALDEHYDE
IATA-DGR: Propionaldehyde
14.3 Transport hazard class(es)
ADR/RID: 3
IMDG: 3
IATA-DGR: 3
IMDG: 3
IATA-DGR: 3
14.4 Packaging group
ADR/RID: II
IMDG: II
IATA-DGR: II
IMDG: II
IATA-DGR: II
14.5 Environmental hazards
ADR/RID: no
IMDG Marine pollutant: no
IATA-DGR: no
IMDG Marine pollutant: no
IATA-DGR: no
14.6 Special precautions for user
Based on chemical properties, choose appropriate tools and conditions of transport.
Transporting tools shall be equipped with appropriate and sufficient firefighting equipment and emergency leaking installations. If transporting by road, please go along the specified route.
Transporting tools shall be equipped with appropriate and sufficient firefighting equipment and emergency leaking installations. If transporting by road, please go along the specified route.
14.7 Incompatible materials
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
National regulatory information
Law on the Prevention and Control of Occupational Diseases
Regulations on Safety Management of Hazardous Chemicals
Catalogue of Hazardous Chemicals : Listed
Other regulations
Please pay attention on the waste treatment should also comply with local regulations requirement.
Law on the Prevention and Control of Occupational Diseases
Regulations on Safety Management of Hazardous Chemicals
Catalogue of Hazardous Chemicals : Listed
Other regulations
Please pay attention on the waste treatment should also comply with local regulations requirement.
Abbreviations and acronyms
CAS: Chemical Abstracts Service
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
Disclaimer:
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.