Chemical Safety Data Sheet MSDS / SDS
Sulfur dioxide
Revision Date:2026-03-21Revision Number:1
Product identifier
- Product name: Sulfur dioxide
- CBnumber: CB4323183
- CAS: 7446-09-5
- EINECS Number: 231-195-2
- Synonyms: SO2;SULPHUR DIOXIDE
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 010-86108875
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
P410+P403 Protect from sunlight. Store in a well-ventilated place.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
Hazard statements
H331 Toxic if inhaled
H314 Causes severe skin burns and eye damage
H280 Contains gas under pressure; may explode if heated
Substance
- Product name: Sulfur dioxide
- Synonyms: SO2;SULPHUR DIOXIDE
- CAS: 7446-09-5
- EC number: 231-195-2
- MF: O2S
- MW: 64.06
General advice
Show this safety data sheet to the doctor in attendance.
If inhaled
After inhalation: fresh air. Immediately call in physician. If breathing stops: immediately apply artificial respiration, if necessary also oxygen.
In case of skin contact
In case of skin contact: Take off immediately all con- taminated clothing. Rinse skin with water/ shower. Call a physician immediately.
In case of eye contact
After eye contact: rinse out with plenty of water. Immediately call in ophthalmologist. Remove contact lenses.
If swallowed
After swallowing: immediately make victim drink water (two glasses at most). Consult a physician.
Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11
Protection of first-aiders
For personal protection see section 8.
Notes to physician
No data available
Suitable extinguishing media
Foam Carbon dioxide (CO2) Dry powder
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.
Specific hazards during fire fighting
Combustible. Pay attention to flashback. Vapours are heavier than air and may spread along floors. Development of hazardous combustion gases or vapours possible in the event of fire. Forms explosive mixtures with air at ambient temperatures.
Hazardous combustion products
Carbon oxides Sulphur oxides
Specific extinguishing methods
Remove container from danger zone and cool with water. Suppress (knock down) gases/vapours/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.
Special protective equipment for fire-fighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
NFPA 704
3
0
0
| HEALTH | 3 | Short exposure could cause serious temporary or moderate residual injury (e.g. liquid hydrogen, sulfuric acid, calcium hypochlorite, hexafluorosilicic acid) | |
| FIRE | 0 | Materials that will not burn under typical fire conditions, including intrinsically noncombustible materials such as concrete, stone, and sand. Materials that will not burn in air when exposed to a temperature of 820 °C (1,500 °F) for a period of 5 minutes.(e.g. Carbon tetrachloride) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Do not breathe vapours, aerosols. Avoid substance contact. Ensure adequate ventilation. Keep away from heat and sources of ignition. Evacuate the danger area, observe emergency procedures, consult an expert. Advice for emergency responders: For personal protection see section 8.
Environmental precautions
Do not let product enter drains. Risk of explosion.
Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up carefully with liquid-absorbent material . Dispose of properly. Clean up affected area.
Handling
Advice on protection against fire and explosionKeep away from open flames, hot surfaces and sources of ignition. Take precautionary measures against static discharge.
Advice on safe handling
Work under hood. Do not inhale substance/mixture. Avoid generation of vapours/aerosols.
Avoidance of contact
Strong oxidizing agents
Storage
Further information on storage conditionsKeep container tightly closed in a dry and wellventilated place. Keep away from heat and sources of ignition.
Storage class
3, Flammable liquids
Recommended storage temperature
Recommended storage temperature see product label.
Further information on storage stability
Test for peroxide formation periodically and before distillation.
Ingredients with workplace control parameters
Biological occupational exposure limits
Engineering measures
No data available
Personal protective equipment
Respiratory protectionrequired when vapours/aerosols are generated.
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Recommended Filter type
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Filter type ABEK
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.
Eye/face protection
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Tightly fitting safety goggles
Skin and body protection
Tightly fitting safety goggles
Flame retardant antistatic protective clothing.
Hand protection
Remarks
required
Hygiene measures
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
Information on basic physicochemical properties
- Dielectric constant17.6（-20℃）
- Solubilitysoluble in H2O, EtOh, ethyl ether,chloroform
- Physical statecolorless gas
- Particle characteristics Particle sizeNo data available
- Oxidizing propertiesnone
- Explosive propertiesNot classified as explosive.
- Flow timeNo data available
- Viscosity, kinematicNo data available
- Viscosity, dynamicNo data available
- Decomposition temperatureNo data available
- Autoignition temperatureNo data available
- Partition coefficient: n-octanol/waterNo data available
- Water solubility%H2O: 17.7 (0°C), 11.9 (15°C), 8.5 (25°C), 6.4 (35°C); % other solvents: 25, alcohol; 32, methanol [MER06]
- Density0.8935 g/cm3
- Relative density1.25 g/mL at 25 °C (lit.)
- Relative vapor density2.26 (21 °C, vs air)
- Vapor pressure1779 mm Hg ( 21 °C)
- Lower explosion limit / Lower flammability limitNo data available
- Upper explosion limit / Upper flammability limitNo data available
- Burning rateNo data available
- Flammability (liquids)No data available
- Flammability (solid, gas)No data available
- Evaporation rateNo data available
- Flash point-17.5 °C
- Boiling point/boiling range-10 °C (lit.)
- Melting point/ rangeNo data available
- pHNo data available
- Odor ThresholdNo data available
- OdorPungent odor detectable at 0.3 to 5 ppm
- Colorcolorless
- Appearanceliquid
Reactivity
Formation of peroxides possible. Vapours may form explosive mixture with air.
Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
Possibility of hazardous reactions
No data available
Conditions to avoid
Warming. Moisture.
Incompatible materials
Strong oxidizing agents
Hazardous decomposition products
Peroxides : In the event of fire: see section 5
11.1 Information on toxicological effects
Mixture Acute toxicityOral: No data available
Acute toxicity estimate Inhalation - 4 h - 25000 ppm - gas(Calculation method)
Symptoms: Possible symptoms:, mucosal irritations, Cough, Shortness of breath,
Possible damages:, damage of respiratory tract
Dermal: No data available
Skin corrosion/irritation
Acute toxicity estimate Inhalation - 4 h - 25000 ppm - gas(Calculation method)
Symptoms: Possible symptoms:, mucosal irritations, Cough, Shortness of breath,
Possible damages:, damage of respiratory tract
Dermal: No data available
Remarks: Mixture causes skin irritation.
Serious eye damage/eye irritation
Remarks: Mixture causes serious eye damage.
Respiratory or skin sensitization
Classified based on available data. For more details, see section 2
Germ cell mutagenicity
Classified based on available data. For more details, see section 2
Carcinogenicity
Evidence of a carcinogenic effect.
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Mixture may cause damage to organs. - Respiratory system
Mixture may cause respiratory irritation.
Mixture may cause drowsiness or dizziness.
Specific target organ toxicity - repeated exposure
Mixture may cause respiratory irritation.
Mixture may cause drowsiness or dizziness.
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2
11.2 Additional Information
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
Other dangerous properties can not be excluded.
This substance should be handled with particular care.
Handle in accordance with good industrial hygiene and safety practice.
Components Tetrahydrofuran
Other dangerous properties can not be excluded.
This substance should be handled with particular care.
Handle in accordance with good industrial hygiene and safety practice.
Acute toxicity
LD50 Oral - Rat - male and female - 1,650 mg/kg
Remarks: (ECHA)
Symptoms: Irritation of mucous membranes
LC50 Inhalation - Rat - male and female - 6 h - > 14.7 mg/l - vapour (US-EPA)
LD50 Dermal - Rat - male and female - > 2,000 mg/kg (OECD Test Guideline 402)
Remarks: (ECHA)
Symptoms: Irritation of mucous membranes
LC50 Inhalation - Rat - male and female - 6 h - > 14.7 mg/l - vapour (US-EPA)
LD50 Dermal - Rat - male and female - > 2,000 mg/kg (OECD Test Guideline 402)
Skin corrosion/irritation
Skin - Rabbit
Result: No skin irritation - 72 h (Draize Test)
Remarks: Repeated or prolonged exposure may cause skin irritation and dermatitis, due to degreasing properties of the product.
Result: No skin irritation - 72 h (Draize Test)
Remarks: Repeated or prolonged exposure may cause skin irritation and dermatitis, due to degreasing properties of the product.
Serious eye damage/eye irritation
Eyes - Rabbit
Result: Causes serious eye irritation.
Remarks: (IUCLID)
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Result: Causes serious eye irritation.
Remarks: (IUCLID)
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Respiratory or skin sensitization
Local lymph node assay (LLNA) - Mouse
Result: negative (OECD Test Guideline 429)
Result: negative (OECD Test Guideline 429)
Germ cell mutagenicity
Test Type: Ames test
Test system: S. typhimurium
Result: negative
Test Type: In vitro mammalian cell gene mutation test
Test system: Chinese hamster ovary cells
Result: negative
Test Type: Chromosome aberration test in vitro
Test system: Chinese hamster ovary cells
Result: negative
Method: OECD Test Guideline 474
Species: Mouse - male and female - Red blood cells (erythrocytes)
Result: negative
Carcinogenicity
Test system: S. typhimurium
Result: negative
Test Type: In vitro mammalian cell gene mutation test
Test system: Chinese hamster ovary cells
Result: negative
Test Type: Chromosome aberration test in vitro
Test system: Chinese hamster ovary cells
Result: negative
Method: OECD Test Guideline 474
Species: Mouse - male and female - Red blood cells (erythrocytes)
Result: negative
Suspected of causing cancer.
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Inhalation - May cause respiratory irritation. - Central nervous system
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
May cause drowsiness or dizziness.
Acute oral toxicity - Irritation of mucous membranes
Specific target organ toxicity - repeated exposure Aspiration hazard
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
May cause drowsiness or dizziness.
Acute oral toxicity - Irritation of mucous membranes
Classified based on available data. For more details, see section 2
Sulphur dioxide Acute toxicity
Oral: No data available
Acute toxicity estimate Inhalation - 1000 ppm - gas (Expert judgement)
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Dermal: No data available
Skin corrosion/irritation
Acute toxicity estimate Inhalation - 1000 ppm - gas (Expert judgement)
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Dermal: No data available
Remarks: Causes skin burns.
Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Serious eye damage/eye irritation
Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Remarks: Causes serious eye damage.
Respiratory or skin sensitization
Classified based on available data. For more details, see section 2
Germ cell mutagenicity
Classified based on available data. For more details, see section 2
Carcinogenicity
Classified based on available data. For more details, see section 2
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Inhalation - Causes damage to organs. - Respiratory system
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Specific target organ toxicity - repeated exposure
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2
Ecotoxicity
Components:
Tetrahydrofuran:
Toxicity to fishLC50 (Pimephales promelas (fathead minnow)): 2,160 mg/l End point: mortality Exposure time: 96 h Test Type: flow-through test Analytical monitoring: yes Method: OECD Test Guideline 203
Toxicity to daphnia and other aquatic invertebrates
EC50 (Daphnia magna (Water flea)): 3,485 mg/l End point: mortality Exposure time: 48 h Test Type: static test Method: OECD Test Guideline 202
Toxicity to fish (Chronic toxicity)
NOEC (Pimephales promelas (fathead minnow)): 216 mg/l End point: Growth inhibition Exposure time: 33 d Test Type: flow-through test Analytical monitoring: yes Remarks: (ECHA)
Persistence and degradability
Components:
Tetrahydrofuran:
Biodegradabilityaerobic Inoculum: activated sludge Concentration: 2 mg/l Biochemical oxygen demand Result: Not readily biodegradable. Biodegradation: 39 % Exposure time: 28 d Method: OECD Test Guideline 301D
Sulphur dioxide:
BiodegradabilityRemarks: The methods for determining the biological degradability are not applicable to inorganic substances.
Bioaccumulative potential
Components:
Tetrahydrofuran:
Partition coefficient: noctanol/waterlog Pow: 0.45 (25 °C) Method: OECD Test Guideline 107 Remarks: Bioaccumulation is not expected.
Sulphur dioxide:
Partition coefficient: noctanol/waterRemarks: Not applicable for inorganic substances
Mobility in soil
No data available
Other adverse effects
Components:
Tetrahydrofuran:
Results of PBT and vPvB assessmentSubstance does not meet the criteria for PBT or vPvB according to Regulation (EC) No 1907/2006, Annex XIII.
Disposal methods
Waste from residuesOffer surplus and non-recyclable solutions to a licensed disposal company.
International Regulations
IATA-DGR
UN/ID No. : UN 2056
Proper shipping name : Tetrahydrofuran solution
Class : 3
Packing group : II
Labels : Class 3 - Flammable liquids
Packing instruction (cargo aircraft) : 364
Packing instruction (passenger aircraft) : 353
Proper shipping name : Tetrahydrofuran solution
Class : 3
Packing group : II
Labels : Class 3 - Flammable liquids
Packing instruction (cargo aircraft) : 364
Packing instruction (passenger aircraft) : 353
IMDG-Code
UN number : UN 2056
Proper shipping name : TETRAHYDROFURAN SOLUTION
Class : 3
Packing group : II
Labels : 3
EmS Code : F-E, S-D
Marine pollutant : no
Proper shipping name : TETRAHYDROFURAN SOLUTION
Class : 3
Packing group : II
Labels : 3
EmS Code : F-E, S-D
Marine pollutant : no
Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code
Not applicable for product as supplied.
National Regulations
JT/T 617
UN number : UN 2056
Proper shipping name : TETRAHYDROFURAN
Class : 3
Packing group : II
Labels : 3
Environmentally hazardous : no
Proper shipping name : TETRAHYDROFURAN
Class : 3
Packing group : II
Labels : 3
Environmentally hazardous : no
Special precautions for user
The transport classification(s) provided herein are for informational purposes only, and solely based upon the properties of the unpackaged material as it is described within this Safety Data Sheet. Transportation classifications may vary by mode of transportation, package sizes, and variations in regional or country regulations.
National regulatory information
Law on the Prevention and Control of Occupational Diseases
Regulations on Safety Management of Hazardous Chemicals
Catalogue of Hazardous Chemicals
Listed
Identification of Major Hazard Installations for Hazardous Chemicals (GB 18218)
No. / Code Chemical name / Category Threshold quantity
W5.3 Flammable liquids 1,000 t
Hazardous Chemicals for Priority Management
Listed under SAWS
Catalogue of Specially Controlled Hazardous
Not listed Chemicals
List of Explosive Precursors
Not listed
Regulations on Labour Protection in Workplaces where Toxic Substances are Used
Catalogue of Highly Toxic Chemicals
Not listed
Regulation of Environmental Management on the First Import of Chemicals and the Import and Export of Toxic Chemicals
China Severely Restricted Toxic Chemicals for Import and Export
Not listed
Regulation on the Administration of Precursor Chemicals
Catalogue and Classification of Precursor Chemicals
Not listed
Regulations on the Administration of Controlled Chemicals
List of Controlled Chemicals
Not listed
Regulations of Ozone Depleting Substances Management
List of Controlled Ozone Depleting Substances
Not listed
List of Controlled Ozone Depleting Substances Import and Export
Not listed
Environmental Protection Law
List of Priority Controlled Chemicals
Not listed
List of Key Controlled New Pollutants
Not listed
Full text of other abbreviations
ACGIHUSA. ACGIH Threshold Limit Values (TLV)
ACGIH BEI
ACGIH - Biological Exposure Indices (BEI)
GBZ 2.1-2007
Occupational exposure limits for hazardous agents in the workplace - Chemical hazardous agents.
ACGIH / TWA
8-hour, time-weighted average
ACGIH / STEL
Short-term exposure limit
GBZ 2.1-2007 / PC-TWA
Permissible concentration - time weighted average
GBZ 2.1-2007 / PC-STEL AIIC - Australian Invent Transport by Land of Bra bw - Body weight; CMR Standard of the German List (Canada); ECx - Conc associated with x% respo Chemical Substances (Jap response; ERG - Emerge GLP - Good Laboratory P cer; IATA - International Construction and Equipm Half maximal inhibitory c tion; IECSC - Inventory o tional Maritime Dangerou Industrial Safety and H Standardization; KECI - K tration to 50 % of a test (Median Lethal Dose); MA lution from Ships; n.o.s. No Observed (Adverse) E fect Level; NOELR - No Norm; NTP - National Toxi icals; OECD - Organizatio fice of Chemical Safety a and Toxic substance; PIC stances; (Q)SAR - (Quant (EC) No 1907/2006 of th Registration, Evaluation, Accelerating Decompositi Chemical Substance Inve Thailand Existing Chemica States); UN - United Nat Transport of Dangerous WHMIS - Workplace Hazar
Permissible concentration - short term exposure limit ry of Industrial Chemicals
ANTT - National Agency for il
ASTM - American Society for the Testing of Materials
- Carcinogen, Mutagen or Reproductive Toxicant
DIN nstitute for Standardisation
DSL - Domestic Substances ntration associated with x% response
ELx - Loading rate se
EmS - Emergency Schedule
ENCS - Existing and New n)
ErCx - Concentration associated with x% growth rate cy Response Guide
GHS - Globally Harmonized System
actice
IARC - International Agency for Research on Canir Transport Association
IBC - International Code for the nt of Ships carrying Dangerous Chemicals in Bulk
IC50 ncentration
ICAO - International Civil Aviation Organiza- Existing Chemical Substances in China
IMDG - Interna- Goods
IMO - International Maritime Organization
ISHL alth Law (Japan)
ISO - International Organisation for rea Existing Chemicals Inventory
LC50 - Lethal Concenopulation
LD50 - Lethal Dose to 50% of a test population POL - International Convention for the Prevention of Pol- Not Otherwise Specified
Nch - Chilean Norm
NO(A)EC fect Concentration
NO(A)EL - No Observed (Adverse) Efbservable Effect Loading Rate
NOM - Official Mexican ology Program
NZIoC - New Zealand Inventory of Chemfor Economic Co-operation and Development
OPPTS - Ofd Pollution Prevention
PBT - Persistent, Bioaccumulative S - Philippines Inventory of Chemicals and Chemical Subtative) Structure Activity Relationship
REACH - Regulation European Parliament and of the Council concerning the uthorisation and Restriction of Chemicals
SADT - Selfn Temperature
SDS - Safety Data Sheet
TCSI - Taiwan tory
TDG - Transportation of Dangerous Goods
TECI s Inventory
TSCA - Toxic Substances Control Act (United ons
UNRTDG - United Nations Recommendations on the oods
vPvB - Very Persistent and Very Bioaccumulative
ous Materials Information System
ANTT - National Agency for il
ASTM - American Society for the Testing of Materials
- Carcinogen, Mutagen or Reproductive Toxicant
DIN nstitute for Standardisation
DSL - Domestic Substances ntration associated with x% response
ELx - Loading rate se
EmS - Emergency Schedule
ENCS - Existing and New n)
ErCx - Concentration associated with x% growth rate cy Response Guide
GHS - Globally Harmonized System
actice
IARC - International Agency for Research on Canir Transport Association
IBC - International Code for the nt of Ships carrying Dangerous Chemicals in Bulk
IC50 ncentration
ICAO - International Civil Aviation Organiza- Existing Chemical Substances in China
IMDG - Interna- Goods
IMO - International Maritime Organization
ISHL alth Law (Japan)
ISO - International Organisation for rea Existing Chemicals Inventory
LC50 - Lethal Concenopulation
LD50 - Lethal Dose to 50% of a test population POL - International Convention for the Prevention of Pol- Not Otherwise Specified
Nch - Chilean Norm
NO(A)EC fect Concentration
NO(A)EL - No Observed (Adverse) Efbservable Effect Loading Rate
NOM - Official Mexican ology Program
NZIoC - New Zealand Inventory of Chemfor Economic Co-operation and Development
OPPTS - Ofd Pollution Prevention
PBT - Persistent, Bioaccumulative S - Philippines Inventory of Chemicals and Chemical Subtative) Structure Activity Relationship
REACH - Regulation European Parliament and of the Council concerning the uthorisation and Restriction of Chemicals
SADT - Selfn Temperature
SDS - Safety Data Sheet
TCSI - Taiwan tory
TDG - Transportation of Dangerous Goods
TECI s Inventory
TSCA - Toxic Substances Control Act (United ons
UNRTDG - United Nations Recommendations on the oods
vPvB - Very Persistent and Very Bioaccumulative
ous Materials Information System
Disclaimer:
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.