11.1 Information on toxicological effects
Acute toxicity
LD50 Oral - Rat - male and female - > 5,000 mg/kg (OECD Test Guideline 401)
LC50 Inhalation - Rat - male and female - 4 h - > 2.42 mg/l - aerosol (OECD Test Guideline 403)
Dermal: No data available
Skin corrosion/irritation
Skin - reconstructed human epidermis (RhE)
Result: No skin irritation (OECD Test Guideline 439)
Serious eye damage/eye irritation
Eyes - Chicken eye
Result: No eye irritation (OECD Test Guideline 438)
Respiratory or skin sensitization
Local lymph node assay (LLNA) - Mouse
Result: positive (OECD Test Guideline 429)
Germ cell mutagenicity
Test Type: Ames test
Test system: Escherichia coli/Salmonella typhimurium
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 471
Result: negative
Test Type: In vitro mammalian cell gene mutation test
Test system: mouse lymphoma cells
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 476
Result: negative
Test Type: Chromosome aberration test in vitro
Test system: Chinese hamster lung cells
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 473
Result: negative
Carcinogenicity
Classified based on available data. For more details, see section 2
Reproductive toxicity
May damage the unborn child.
Suspected of damaging fertility.
Studies indicating a hazard to babies during the lactation period
Specific target organ toxicity - single exposure
Classified based on available data. For more details, see section 2
Specific target organ toxicity - repeated exposure
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2
11.2 Additional Information
Repeated dose toxicity - Rat - male and female - Oral - 13 Weeks - NOAEL (No observed adverse effect level) - >= 100 mg/kg
RTECS: WY2625000
Nausea, Headache, Vomiting, Central nervous system depression
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
The following applies to tellurium compounds in general: after oral uptake, the compound is mostly reduced to metallic tellurium and subsequently eliminated with the faeces (blue- grey). After inhalation or ingestion: metallic taste, dryness in mouth. Possible in extreme cases: gastrointestinal complaints, cyanosis, unconsciousness, collapse, in some cases risk of liver and kidney damage.