Chemical Safety Data Sheet MSDS / SDS

Testosterone

Revision Date:2026-03-21Revision Number:1

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier

  • Product name: Testosterone
  • CBnumber: CB5380541
  • CAS: 58-22-0
  • EINECS Number: 200-370-5
  • Synonyms: TESTOSTERON;Sustanon

Relevant identified uses of the substance or mixture and uses advised against

  • Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
  • Uses advised against: none

Company Identification

  • Company: Chemicalbook
  • Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
  • Telephone: 010-86108875

SECTION 2: Hazards identification

GHS Label elements, including precautionary statements

  • Symbol(GHS)
  • Signal wordDanger
Precautionary statements
P202 Do not handle until all safety precautions have been read and understood.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P308+P313 IF exposed or concerned: Get medical advice/attention.
Hazard statements
H302 Harmful if swallowed
H351 Suspected of causing cancer
H400 Very toxic to aquatic life

SECTION 3: Composition/information on ingredients

Substance

  • Product name: Testosterone
  • Synonyms: TESTOSTERON;Sustanon
  • CAS: 58-22-0
  • EC number: 200-370-5
  • MF: C19H28O2
  • MW: 288.43

SECTION 4: First aid measures

4.1 Description of first-aid measures

General advice
Show this material safety data sheet to the doctor in attendance.
If inhaled
After inhalation: fresh air. If breathing stops: mouth-to-mouth breathing or artificial respiration. Oxygen if necessary. Immediately call in physician.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. Consult a physician.
In case of eye contact
After eye contact: rinse out with plenty of water. Call in ophthalmologist. Remove contact lenses.
If swallowed
After swallowing: immediately make victim drink water (two glasses at most). Consult a physician.

4.2 Most important symptoms and effects, both acute and delayed

The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11

4.3 Indication of any immediate medical attention and special treatment needed

No data available

SECTION 5: Firefighting measures

5.1 Extinguishing media

Suitable extinguishing media
Foam Carbon dioxide (CO2) Dry powder
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.

5.2 Special hazards arising from the substance or mixture

Carbon oxides
Nitrogen oxides (NOx)
Combustible.
Pay attention to flashback.
Vapors are heavier than air and may spread along floors.
Development of hazardous combustion gases or vapours possible in the event of fire.
Forms explosive mixtures with air at ambient temperatures.

5.3 Advice for firefighters

Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.

5.4 Further information

Remove container from danger zone and cool with water. Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.

NFPA 704

2
0
0
HEALTH 2 Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury (e.g. diethyl ether, ammonium phosphate, iodine)
FIRE 0 Materials that will not burn under typical fire conditions, including intrinsically noncombustible materials such as concrete, stone, and sand. Materials that will not burn in air when exposed to a temperature of 820 °C (1,500 °F) for a period of 5 minutes.(e.g. Carbon tetrachloride)
REACT 0 Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2)
SPEC. HAZ.

SECTION 6: Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Keep away from heat and sources of ignition.
Evacuate the danger area, observe emergency procedures, consult an expert.
For personal protection see section 8.

6.2 Environmental precautions

Do not let product enter drains. Risk of explosion.

6.3 Methods and materials for containment and cleaning up

Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up with liquid-absorbent material (e.g. Chemizorb® ).
Dispose of properly. Clean up affected area.

6.4 Reference to other sections

For disposal see section 13.

SECTION 7: Handling and storage

7.1 Precautions for safe handling

Advice on safe handling
Work under hood. Do not inhale substance/mixture. Avoid generation of vapours/aerosols.
Advice on protection against fire and explosion
Keep away from open flames, hot surfaces and sources of ignition.Take precautionary measures against static discharge.
Hygiene measures
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
For precautions see section 2.2.

7.2 Conditions for safe storage, including any incompatibilities

Storage conditions
Keep container tightly closed in a dry and well-ventilated place. Keep away from heat and sources of ignition.
Storage stabilityRecommended storage temperature
-20 °C
Storage class
Storage class (TRGS 510): 3: Flammable liquids

7.3 Specific end use(s)

Apart from the uses mentioned in section 1.2 no other specific uses are stipulated

SECTION 8: Exposure controls/personal protection

8.1 Control parameters

Ingredients with workplace control parameters

8.2 Exposure controls

Personal protective equipment
Eye/face protection
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses
Skin protection
required
Body Protection
Flame retardant antistatic protective clothing.
Respiratory protection
required when vapours/aerosols are generated.
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Recommended Filter type: Filter type ABEK
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer.
These measures have to be properly documented.
Control of environmental exposure
Do not let product enter drains. Risk of explosion.

SECTION 9: Physical and chemical properties

Information on basic physicochemical properties

  • a) Physical stateliquid
  • b) ColorNo data available
  • c) OdorNo data available
  • d) Melting point/freezing pointNo data available
  • e) Initial boiling point and boiling range81 - 82 °C at 1,013 hPa
  • f) Flammability (solid, gas)No data available
  • g) Upper/lower flammability or explosive limitsUpper explosion limit: 16 %(V)
    Lower explosion limit: 4,4 %(V)
  • h) Flash point2 °C - closed cup
  • i) Autoignition temperatureNo data available
  • j) Decomposition temperatureNo data available
  • k) pHNo data available
  • l) ViscosityViscosity, kinematic: No data available
    Viscosity, dynamic: No data available
  • m) Water solubility22.79mg/L(20 ºC)
  • n) Partition coefficient n-octanol/waterNo data available
  • o) Vapor pressureNo data available
  • p) Density0,782 g/cm3 at 20 °C
  • Relative density1.0484 (rough estimate)
  • q) Relative vapor densityNo data available
  • r) Particle characteristicsNo data available
  • s) Explosive propertiesNot classified as explosive.
  • t) Oxidizing propertiesnone
  • Solubility45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble18.2 mg/ml

9.2 Other safety information

No data available

SECTION 10: Stability and reactivity

10.1 Reactivity

Vapors may form explosive mixture with air.

10.2 Chemical stability

The product is chemically stable under standard ambient conditions (room temperature) .

10.3 Possibility of hazardous reactions

No data available

10.4 Conditions to avoid

Warming.

10.5 Incompatible materials

acids, Bases, Oxidizing agents, Alkali metals

10.6 Hazardous decomposition products

In the event of fire: see section 5

SECTION 11: Toxicological information

11.1 Information on toxicological effects

Mixture Acute toxicity
Oral: No data available
Acute toxicity estimate Inhalation - 4 h - 11,01 mg/l - vapor(Calculation method)
Symptoms: Possible symptoms:, mucosal irritations
Acute toxicity estimate Dermal - 1.502 mg/kg (Calculation method)
Skin corrosion/irritation
Classified based on available data. For more details, see section 2
Serious eye damage/eye irritation
Remarks: Mixture causes serious eye irritation.
Respiratory or skin sensitization
Classified based on available data. For more details, see section 2
Germ cell mutagenicity
Classified based on available data. For more details, see section 2
Carcinogenicity
Classified based on available data. For more details, see section 2
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Classified based on available data. For more details, see section 2
Specific target organ toxicity - repeated exposure
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2

11.2 Additional Information

Endocrine disrupting properties
Product:
Assessment : The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
Treat as cyanide poisoning., Always have on hand a cyanide first-aid kit, together with proper instructions., The onset of symptoms is generally delayed pending conversion to cyanide., Nausea, Vomiting, Diarrhea, Headache, Dizziness, Rash, Cyanosis
Other dangerous properties can not be excluded.
Handle in accordance with good industrial hygiene and safety practice.
Components Acetonitrile
Acute toxicity
LD50 Oral - Mouse - male and female - 617 mg/kg (OECD Test Guideline 401)
Acute toxicity estimate Oral - 617 mg/kg (ATE value derived from LD50/LC50 value)
LC50 Inhalation - Mouse - male and female - 4 h - 6,022 mg/l - vapor (OECD Test Guideline 403)
Acute toxicity estimate Dermal - 1.500 mg/kg (Expert judgment)
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Skin corrosion/irritation
Skin - Rabbit
Result: No skin irritation - 4 h (OECD Test Guideline 404)
Serious eye damage/eye irritation
Eyes - Rabbit
Result: Causes serious eye irritation.
(OECD Test Guideline 405)
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Respiratory or skin sensitization
Buehler Test - Guinea pig
Result: negative (OECD Test Guideline 406)
Germ cell mutagenicity
Test Type: Ames test
Test system: S. typhimurium
Result: negative
Remarks: (ECHA)
Test Type: In vitro mammalian cell gene mutation test
Test system: Chinese hamster ovary cells
Result: negative
Test Type: Mutagenicity (mammal cell test): chromosome aberration.
Test system: Chinese hamster ovary cells
Result: Positive results were obtained in some in vitro tests.
Remarks: (National Toxicology Program)
Test Type: sister chromatid exchange assay
Test system: Chinese hamster ovary cells
Result: negative
Remarks: Sister chromatid exchange
Test system: Saccharomyces cerevisiae
Result: positive
Remarks: Cytogenetic analysis (ECHA)
Test Type: In vitro mammalian cell gene mutation test
Test system: Mouse lymphoma test
Result: negative
Method: OECD Test Guideline 474
Species: Mouse - male and female
Result: negative
Carcinogenicity
No evidence of carcinogenicity in animal studies.
Reproductive toxicity
Animal testing did not show any effects on fertility.
Specific target organ toxicity - single exposure
The substance or mixture is not classified as specific target organ toxicant, single exposure.
Specific target organ toxicity - repeated exposure
The substance or mixture is not classified as specific target organ toxicant, repeated exposure.
Aspiration hazard
No aspiration toxicity classification
Testosterone Acute toxicity
LD50 Oral - Rat - male - 500 - 1.000 mg/kg (OECD Test Guideline 423)
The value is given in analogy to the following substances: 4-Androstene-3,17-dione
Inhalation: No data available
LD50 Dermal - Rat - male and female - > 2.000 mg/kg (OECD Test Guideline 402)
The value is given in analogy to the following substances: 4-Androstene-3,17-dione
Skin corrosion/irritation
Skin - Rat
Result: No skin irritation - 24 h
Remarks: (ECHA) (in analogy to similar products)
The value is given in analogy to the following substances: 4-Androstene-3,17-dione
Serious eye damage/eye irritation
Eyes - Rabbit
Result: No eye irritation (OECD Test Guideline 405)
Remarks: (in analogy to similar products)
The value is given in analogy to the following substances: 4-Androstene-3,17-dione
Respiratory or skin sensitization
Maximization Test - Guinea pig
Result: negative (OECD Test Guideline 406)
Remarks: (in analogy to similar products)
The value is given in analogy to the following substances: 4-Androstene-3,17-dione
Germ cell mutagenicity
Classified based on available data. For more details, see section 2
Carcinogenicity
Suspected of causing cancer.
Reproductive toxicity
May damage the unborn child.
May damage fertility.
Specific target organ toxicity - single exposure
Classified based on available data. For more details, see section 2
Specific target organ toxicity - repeated exposure
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2

SECTION 12: Ecological information

12.1 Toxicity

Mixture
No data available

12.2 Persistence and degradability

No data available

12.3 Bioaccumulative potential

No data available

12.4 Mobility in soil

No data available

12.5 Results of PBT and vPvB assessment

This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

12.6 Endocrine disrupting properties

Product:
Assessment : The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission
Delegated regulation (EU) 2017/2100 or Commission
Regulation (EU) 2018/605 at levels of 0.1% or higher.

12.7 Other adverse effects

No data available
Components Acetonitrile
Toxicity to fish flow-through test LC50 - Pimephales promelas (fathead minnow) - 1.640 mg/l - 96 h
Remarks: (ECHA)
Toxicity to algae static test NOEC - Phaeodactylum tricornutum - 400 mg/l - 72 h (ISO 10253) static test ErC50 - Phaeodactylum tricornutum - 9.696 mg/l - 72 h (ISO 10253)
Toxicity to bacteria
Toxicity to flow-through test NOEC - Oryzias latipes - 102 mg/l - 21 d fish(Chronic toxicity) (OECD Test Guideline 204)
Testosterone
Toxicity to daphnia static test NOEC - Daphnia magna (Water flea) - > 6,2 mg/l - and other aquatic 48 h invertebrates (OECD Test Guideline 202)
Toxicity to algae static test ErC50 - Desmodesmus subspicatus (green algae) - 0,7 mg/l - 72 h (OECD Test Guideline 201)

SECTION 13: Disposal considerations

13.1 Waste treatment methods

No data available

SECTION 14: Transport information

14.1 UN number

ADR/RID: 1648
IMDG: 1648
IATA: 1648

14.2 UN proper shipping name

ADR/RID: ACETONITRILE, SOLUTION
IMDG: ACETONITRILE, SOLUTION
IATA: Acetonitrile, SOLUTION

14.3 Transport hazard class(es)

ADR/RID: 3
IMDG: 3
IATA: 3

14.4 Packaging group

ADR/RID: II
IMDG: II
IATA: II

14.5 Environmental hazards

ADR/RID: no
IMDG Marine pollutant: no
IATA: no

14.6 Special precautions for user

Tunnel restriction code : (D/E)
Further information : No data available

SECTION 15: Regulatory information

15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture

This material safety data sheet complies with the requirements of Regulation (EC) No.
1907/2006.
Authorisations and/or restrictions on use National legislation
Seveso III: Directive 2012/18/EU of the P5c FLAMMABLE LIQUIDS
European Parliament and of the Council on the control of major-accident hazards involving dangerous substances.
Other regulations
Observe work restrictions regarding maternity protection in accordance to Dir 92/85/EEC or stricter national regulations where applicable.
Take note of Dir 94/33/EC on the protection of young people at work.

15.2 Chemical Safety Assessment

For this product a chemical safety assessment was not carried out

SECTION 16: Other information

Full text of other abbreviations

ADN - European Agreement concerning the International Carriage of Dangerous Goods by Inland Waterways
ADR - Agreement concerning the International Carriage ofDangerous Goods by Road
AIIC - Australian Inventory of Industrial Chemicals
ASTM -American Society for the Testing of Materials
bw - Body weight
CMR - Carcinogen,Mutagen or Reproductive Toxicant
DIN - Standard of the German Institute forStandardisation
DSL - Domestic Substances List (Canada)
ECx - Concentration associated with x% response
ELx - Loading rate associated with x% response
EmS -Emergency Schedule
ENCS - Existing and New Chemical Substances (Japan)
ErCx -Concentration associated with x% growth rate response
GHS - Globally HarmonizedSystem
GLP - Good Laboratory Practice
IARC - International Agency for Research onCancer
IATA - International Air Transport Association
IBC - International Code for theConstruction and Equipment of Ships carrying Dangerous Chemicals in Bulk
IC50 - Half maximal inhibitory concentration
ICAO - International Civil Aviation Organization
IECSC - Inventory of Existing Chemical Substances in China
IMDG - InternationalMaritime Dangerous Goods
IMO - International Maritime Organization
ISHL - IndustrialSafety and Health Law (Japan)
ISO - International Organisation for Standardization
KECI - Korea Existing Chemicals Inventory
LC50 - Lethal Concentration to 50 % of a test population
LD50 - Lethal Dose to 50% of a test population (Median Lethal Dose)
MARPOL - International Convention for the Prevention of Pollution from Ships
n.o.s. -Not Otherwise Specified
NO(A)EC - No Observed (Adverse) Effect Concentration
NO(A)EL - No Observed (Adverse) Effect Level
NOELR - No Observable Effect LoadingRate
NZIoC - New Zealand Inventory of Chemicals
OECD - Organization for EconomicCo-operation and Development
OPPTS - Office of Chemical Safety and PollutionPrevention
PBT - Persistent, Bioaccumulative and Toxic substance
PICCS - PhilippinesInventory of Chemicals and Chemical Substances
(Q)SAR - (Quantitative) StructureActivity Relationship
REACH - Regulation (EC) No 1907/2006 of the EuropeanParliament and of the Council concerning the Registration, Evaluation, Authorisation andRestriction of Chemicals
RID - Regulations concerning the International Carriage ofDangerous Goods by Rail
SADT - Self-Accelerating Decomposition Temperature
SDS -Safety Data Sheet
TCSI - Taiwan Chemical Substance Inventory
TECI - ThailandExisting Chemicals Inventory
TSCA - Toxic Substances Control Act (United States)
UN - United Nations
UNRTDG - United Nations Recommendations on the Transport ofDangerous Goods
vPvB - Very Persistent and Very Bioaccumulative
Disclaimer:

The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.

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