Chemical Safety Data Sheet MSDS / SDS
Tri(propylene glycol) diacrylate
Revision Date:2026-03-21Revision Number:1
Product identifier
- Product name: Tri(propylene glycol) diacrylate
- CBnumber: CB1301197
- CAS: 42978-66-5
- EINECS Number: 256-032-2
- Synonyms: TPGDA;TRIPROPYLENE GLYCOL DIACRYLATE
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 010-86108875
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordWarning
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash skin thouroughly after handling.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
Hazard statements
H315 Causes skin irritation
H317 May cause an allergic skin reaction
H319 Causes serious eye irritation
H335 May cause respiratory irritation
H411 Toxic to aquatic life with long lasting effects
Substance
- Product name: Tri(propylene glycol) diacrylate
- Synonyms: TPGDA;TRIPROPYLENE GLYCOL DIACRYLATE
- CAS: 42978-66-5
- EC number: 256-032-2
- MF: C15H24O6
- MW: 300.35
4.1 Description of first-aid measures
General adviceShow this material safety data sheet to the doctor in attendance.
If inhaled
After inhalation: fresh air.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. Consult a physician.
In case of eye contact
After eye contact: rinse out with plenty of water. Call in ophthalmologist. Remove contact lenses.
If swallowed
After swallowing: caution if victim vomits. Risk of aspiration! Keep airways free. Pulmonary failure possible after aspiration of vomit. Call a physician immediately.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available
4.4 Notes to physician
No data available
5.1 Extinguishing media
Suitable extinguishing mediaWater Foam Carbon dioxide (CO2) Dry powder
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.
5.2 Special hazards arising from the substance or mixture
Carbon oxides
Combustible.
Vapors are heavier than air and may spread along floors.
Forms explosive mixtures with air on intense heating.
Development of hazardous combustion gases or vapours possible in the event of fire.
Combustible.
Vapors are heavier than air and may spread along floors.
Forms explosive mixtures with air on intense heating.
Development of hazardous combustion gases or vapours possible in the event of fire.
5.3 Advice for firefighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
Prevent fire extinguishing water from contaminating surface water or the ground water system.
Prevent fire extinguishing water from contaminating surface water or the ground water system.
NFPA 704
1
1
0
| HEALTH | 1 | Exposure would cause irritation with only minor residual injury (e.g. acetone, sodium bromate, potassium chloride) | |
| FIRE | 1 | Materials that require considerable preheating, under all ambient temperature conditions, before ignition and combustion can occur. Includes some finely divided suspended solids that do not require heating before ignition can occur. Flash point at or above 93.3 °C (200 °F). (e.g. mineral oil, ammonia) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
6.1 Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert.
For personal protection see section 8.
For personal protection see section 8.
6.2 Environmental precautions
Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up with liquid-absorbent material (e.g. Chemizorb® ).
Dispose of properly. Clean up affected area.
Dispose of properly. Clean up affected area.
6.4 Reference to other sections
For disposal see section 13.
7.1 Precautions for safe handling
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Storage conditionsTightly closed.
Light sensitive. Hygroscopic.
Storage class
Light sensitive. Hygroscopic.
Storage class (TRGS 510): 10: Combustible liquids
8.1 Control parameters
Ingredients with workplace control parametersContains no substances with occupational exposure limit values.
8.2 Exposure controls
Appropriate engineering controlsImmediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
Personal protective equipment
Eye/face protection
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses
Skin protection
required
Body Protection
protective clothing
Respiratory protection
required when vapours/aerosols are generated.
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Control of environmental exposure
Do not let product enter drains.
Information on basic physicochemical properties
- a) Physical stateliquid
- b) Colorlight yellow
- c) OdorNo data available
- d) Melting point/freezing pointMelting point/range: < -20 °C - (ECHA)
- e) Initial boiling point and boiling range> 120 °C at 1,013.25 hPa - (ECHA)
- f) Flammability (solid, gas)No data available
- g) Upper/lower flammability or explosive limitsNo data available
- h) Flash point153 °C - closed cup - ISO 2719
- i) Autoignition temperature214 °C at 1,000 hPa
- j) Decomposition temperatureNo data available
- k) pHNo data available
- l) ViscosityViscosity, kinematic: 14.5 mm2/s at 20 °C - OECD Test
Guideline 1146.7 mm2/s at 40 °C - OECD Test Guideline 114
Viscosity, dynamic: 15.1 mPa.s at 20 °C - OECD Test Guideline 1146.85 mPa.s at 40 °C - OECD Test Guideline 114 - m) Water solubility4 g/l at 20 °C - OECD Test Guideline 105
- n) Partition coefficient n-octanol/waterlog Pow: > 2.5 - < 2.7 at 23 °C - Bioaccumulation is not expected.
- o) Vapor pressure< 0.01 hPa at 20 °C
- p) Density1.03 g/cm3 at 25 °C - lit.
- Relative density1.03 g/mL at 25 °C(lit.)
- q) Relative vapor density>1 (vs air)
- r) Particle characteristicsNo data available
- s) Explosive propertiesNo data available
- t) Oxidizing propertiesnone
- SolubilityChloroform, Methanol (Slightly)
9.2 Other safety information
Relative vapor density10.36 - (Air = 1.0)
10.1 Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
10.2 Possibility of hazardous reactions
No data available
10.3 Conditions to avoid
May polymerize on exposure to light. Avoid moisture.
Strong heating.
Strong heating.
10.4 Incompatible materials
Oxidizing agentsStrong acids, Strong oxidizing agents, Strong bases, Brass, Copper, Steel (all types and surface treatments), Iron and iron salts.
10.5 Hazardous decomposition products
In the event of fire: see section 5
11.1 Information on toxicological effects
Acute toxicityLD50 Oral - Rat - female - > 2,000 mg/kg (Tri(propylene glycol) diacrylate, mixture of isomers) (OECD Test Guideline 423)
Inhalation: No data available
LD50 Dermal - Rabbit - male and female - > 2,000 mg/kg (Tri(propylene glycol) diacrylate, mixture of isomers) (OECD Test Guideline 402)
Skin corrosion/irritation
Inhalation: No data available
LD50 Dermal - Rabbit - male and female - > 2,000 mg/kg (Tri(propylene glycol) diacrylate, mixture of isomers) (OECD Test Guideline 402)
Remarks: Causes skin irritation.
Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Serious eye damage/eye irritation
Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Eyes - Rabbit (Tri(propylene glycol) diacrylate, mixture of isomers)
Result: Mild eye irritation - 24 h (OECD Test Guideline 405)
Remarks: Causes serious eye irritation.
Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Respiratory or skin sensitization
Result: Mild eye irritation - 24 h (OECD Test Guideline 405)
Remarks: Causes serious eye irritation.
Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Local lymph node assay (LLNA) - Mouse (Tri(propylene glycol) diacrylate, mixture of isomers)
Result: positive (OECD Test Guideline 429)
May cause an allergic skin reaction. Classified according to Regulation (EU) 1272/2008,
Annex VI (Table 3.1/3.2) (Tri(propylene glycol) diacrylate, mixture of isomers)
Germ cell mutagenicity
Result: positive (OECD Test Guideline 429)
May cause an allergic skin reaction. Classified according to Regulation (EU) 1272/2008,
Annex VI (Table 3.1/3.2) (Tri(propylene glycol) diacrylate, mixture of isomers)
Test Type: gene mutation test (Tri(propylene glycol) diacrylate, mixture of isomers)
Test system: Chinese hamster ovary cells
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 476
Result: negative
Test Type: In vitro mammalian cell gene mutation test (Tri(propylene glycol) diacrylate, mixture of isomers)
Test system: mouse lymphoma cells
Metabolic activation: with and without metabolic activation
Result: positive
Remarks: (ECHA) (Tri(propylene glycol) diacrylate, mixture of isomers)
Test Type: In vivo micronucleus test
Species: Mouse
Application Route: Intraperitoneal
Method: OECD Test Guideline 474
Result: negative
Carcinogenicity
Test system: Chinese hamster ovary cells
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 476
Result: negative
Test Type: In vitro mammalian cell gene mutation test (Tri(propylene glycol) diacrylate, mixture of isomers)
Test system: mouse lymphoma cells
Metabolic activation: with and without metabolic activation
Result: positive
Remarks: (ECHA) (Tri(propylene glycol) diacrylate, mixture of isomers)
Test Type: In vivo micronucleus test
Species: Mouse
Application Route: Intraperitoneal
Method: OECD Test Guideline 474
Result: negative
Classified based on available data. For more details, see section 2
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
May cause respiratory irritation. - Respiratory system (Tri(propylene glycol) diacrylate, mixture of isomers)
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Specific target organ toxicity - repeated exposure
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2
11.2 Additional Information
Repeated dose toxicity - Rat - male and female - Oral - NOAEL (No observed adverse effect level) - 375 mg/kg (Tri(propylene glycol) diacrylate, mixture of isomers)
Repeated dose toxicity - Rat - male and female - Dermal - 90 d - LOAEL (Lowest observed adverse effect level) - 20 mg/kg (Tri(propylene glycol) diacrylate, mixture of isomers)
RTECS: AT4690000
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated. (Tri(propylene glycol) diacrylate, mixture of isomers)
Repeated dose toxicity - Rat - male and female - Dermal - 90 d - LOAEL (Lowest observed adverse effect level) - 20 mg/kg (Tri(propylene glycol) diacrylate, mixture of isomers)
RTECS: AT4690000
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated. (Tri(propylene glycol) diacrylate, mixture of isomers)
12.1 Toxicity
Toxicity to fish static test LC50 - Leuciscus idus (Golden orfe) - > 4.6 - < 10 mg/l - 96 h (Tri(propylene glycol) diacrylate, mixture of isomers) (DIN 38412)
Toxicity to daphnia static test EC50 - Daphnia magna Straus (Water flea) - 89 mg/l - 48 and other aquatic h (Tri(propylene glycol) diacrylate, mixture of isomers) invertebrates (Regulation (EC) No. 440/2008, Annex, C.2)
Toxicity to algae static test ErC50 - Desmodesmus subspicatus (green algae) - 65.9 mg/l - 72 h (Tri(propylene glycol) diacrylate, mixture of isomers) (DIN 38412)
Toxicity to bacteria Respiration inhibition EC50 - Sludge Treatment - > 1,000 mg/l - 30 min (Tri(propylene glycol) diacrylate, mixture of isomers) (OECD Test Guideline 209)
Toxicity to daphnia static test EC50 - Daphnia magna Straus (Water flea) - 89 mg/l - 48 and other aquatic h (Tri(propylene glycol) diacrylate, mixture of isomers) invertebrates (Regulation (EC) No. 440/2008, Annex, C.2)
Toxicity to algae static test ErC50 - Desmodesmus subspicatus (green algae) - 65.9 mg/l - 72 h (Tri(propylene glycol) diacrylate, mixture of isomers) (DIN 38412)
Toxicity to bacteria Respiration inhibition EC50 - Sludge Treatment - > 1,000 mg/l - 30 min (Tri(propylene glycol) diacrylate, mixture of isomers) (OECD Test Guideline 209)
12.2 Persistence and degradability
Biodegradability aerobic - Exposure time 28 d (Tri(propylene glycol) diacrylate, mixture of isomers)
Result: 48 % - Partially biodegradable.
(OECD Test Guideline 301B)
Result: 48 % - Partially biodegradable.
(OECD Test Guideline 301B)
12.3 Bioaccumulative potential
No data available
12.4 Mobility in soil
No data available
12.5 Results of PBT and vPvB assessment
PBT/vPvB assessment not available as chemical safety assessment not required/not conducted
12.6 Endocrine disrupting properties
No data available
12.7 Other adverse effects
No data available
13.1 Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company.
Offer surplus and non-recyclable solutions to a licensed disposal company.
14.1 UN number
ADR/RID: 3082
IMDG: 3082
IATA-DGR: 3082
IMDG: 3082
IATA-DGR: 3082
14.2 UN proper shipping name
ADR/RID: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S. (Tri(propylene glycol) diacrylate, mixture of isomers)
IMDG: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S. (Tri(propylene glycol) diacrylate, mixture of isomers)
IATA-DGR: Environmentally hazardous substance, liquid, n.o.s. (Tri(propylene glycol) diacrylate, mixture of isomers)
IMDG: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S. (Tri(propylene glycol) diacrylate, mixture of isomers)
IATA-DGR: Environmentally hazardous substance, liquid, n.o.s. (Tri(propylene glycol) diacrylate, mixture of isomers)
14.3 Transport hazard class(es)
ADR/RID: 9
IMDG: 9
IATA-DGR: 9
IMDG: 9
IATA-DGR: 9
14.4 Packaging group
ADR/RID: III
IMDG: III
IATA-DGR: III
IMDG: III
IATA-DGR: III
14.5 Environmental hazards
ADR/RID: yes
IMDG Marine pollutant: yes
IATA-DGR: yes
IMDG Marine pollutant: yes
IATA-DGR: yes
14.6 Special precautions for user
14.7 Incompatible materials
Oxidizing agentsStrong acids, Strong oxidizing agents, Strong bases, Brass, Copper, Steel (all types and surface treatments), Iron and iron salts.
Further information: Packages smaller than or equal to 5 kg / L , not dangerous goods of Class 9
Further information: Packages smaller than or equal to 5 kg / L , not dangerous goods of Class 9
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
National regulatory information
Other regulations
Please pay attention on the waste treatment should also comply with local regulations requirement.
Other regulations
Please pay attention on the waste treatment should also comply with local regulations requirement.
Abbreviations and acronyms
CAS: Chemical Abstracts Service
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
Disclaimer:
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.
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