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ChemicalBook CAS DataBase List (1R)-2,2,2-TRIFLUORO-1-(2-PYRIDYL)ETHYLAMINE
1228565-87-4

(1R)-2,2,2-TRIFLUORO-1-(2-PYRIDYL)ETHYLAMINE synthesis

1synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 4.5 h / 0 °C
1.2: ChiralPak AD
2.1: trifluorormethanesulfonic acid; trifluoroacetic acid / dichloromethane / 26 h / 0 - 20 °C

References:

US2013/109665,2013,A1

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