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Technical Data Sheet AZD 9668

Compound Information
Product Name: AZD 9668
CAS No.: 848141-11-7
Molecular Formula: C25H22F3N5O4S
Molecular Weight: 545.53
Storage: Store the product in sealed, cool and dry condition.
Revision Date: 2026-04-27
Analytical Information
Tests Specifications
Description Alvelestat (AZD9668) is an oral, highly selective inhibitor of neutrophil elastase (NE) with IC50 and Ki of 12 nM and 9.4 nM, at least 600-fold more selective over other serine proteases.
Form Solid
Color White
Purity >98%
General tips For obtaining a higher solubility, please warm the tube at 37 degrees Celsius (98.6 degrees Fahrenheit) and shake it in the ultrasonic bath for a while.
Solubility DMSO ≥ 60 mg/mL
NMR Pass test
Disclaimer: This information relates only to the specific material designated and may not be valid for such material used in combination with anyother materials or in any other process. Such information is to be the best of the company's knowledge and believed accurate and reliable as of thedate indicated. However, no representation, warranty or guarantee of any kind, express or implied, is made as to its accuracy, reliability orcompleteness and we assume no responsibility for any loss, damage or expense, direct or consequential, arising out of use. It is the user'sresponsibility to satisfy himself as to the suitableness & completeness of such information for his own particular use.
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