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Technical Data Sheet CO-1686

Compound Information
Product Name: CO-1686
CAS No.: 1374640-70-6
Molecular Formula: C27H28F3N7O3
Molecular Weight: 555.55
Storage: Store the product in sealed, cool and dry condition.
Revision Date: 2026-04-27
Analytical Information
Tests Specifications
Description Rociletinib (CO-1686) is a potent, novel inhibitor of EGFR L858R/T790M kinase with Ki of 21.5 nM and 303.3 nM, respectively.
Form Solid
Color Off-White
Purity >98%
General tips For obtaining a higher solubility, please warm the tube at 37 degrees Celsius (98.6 degrees Fahrenheit) and shake it in the ultrasonic bath for a while.
Solubility DMSO 50 mg/mL
NMR Pass test
Disclaimer: This information relates only to the specific material designated and may not be valid for such material used in combination with anyother materials or in any other process. Such information is to be the best of the company's knowledge and believed accurate and reliable as of thedate indicated. However, no representation, warranty or guarantee of any kind, express or implied, is made as to its accuracy, reliability orcompleteness and we assume no responsibility for any loss, damage or expense, direct or consequential, arising out of use. It is the user'sresponsibility to satisfy himself as to the suitableness & completeness of such information for his own particular use.
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