PDF
Technical Data Sheet EGF816
Compound Information
Product Name:
EGF816
CAS No.:
1508250-71-2
Molecular Formula:
C26H31ClN6O2
Molecular Weight:
495.02
Storage:
Store the product in sealed, cool and dry condition.
Revision Date:
2026-04-27
Analytical Information
| Tests | Specifications |
|---|---|
| Description | Nazartinib (EGF816, NVS-816) is a covalent, irreversible, mutant-selective EGFR inhibitor that has nanomolar inhibitory potency against activating mt (L858R, ex19del) and T790M mt, with up to 60-fold selectivity over wild type (wt) EGFR in vitro. |
| Form | Powder |
| Color | Off-white to yellow |
| Purity | >98% |
| General tips | For obtaining a higher solubility, please warm the tube at 37 degrees Celsius (98.6 degrees Fahrenheit) and shake it in the ultrasonic bath for a while. |
| Solubility | 99 mg/mL in DMSO |
Disclaimer: This information relates only to the specific material designated and may not be valid for such material used in combination with anyother materials or in any other process. Such information is to be the best of the company's knowledge and believed accurate and reliable as of thedate indicated. However, no representation, warranty or guarantee of any kind, express or implied, is made as to its accuracy, reliability orcompleteness and we assume no responsibility for any loss, damage or expense, direct or consequential, arising out of use. It is the user'sresponsibility to satisfy himself as to the suitableness & completeness of such information for his own particular use.
ChemicalBook