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Technical Data Sheet FM26

Compound Information
Product Name: FM26
CAS No.: 2407981-35-3
Molecular Formula: C22H15ClF3N3O3
Molecular Weight: 461.82
Revision Date: 2026-04-15
Analytical Information
Tests Specifications
Description FM26 (compound 25) is a potent and allosteric retinoic acid receptor-related orphan receptor γt (RORγt) inverse agonists with an IC50 of 264 nM. FM26 has a distinct isoxazole chemotype and effectively reduces IL-17a mRNA production in EL4 cells.
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