PDF
Technical Data Sheet Leptomycin B
Compound Information
Product Name:
Leptomycin B
CAS No.:
87081-35-4
Molecular Formula:
C33H48O6
Molecular Weight:
540.73
Storage:
Powder -20°C 3 years; 4°C 2 years
In solvent -80°C 6 months; -20°C 1 month
In solvent -80°C 6 months; -20°C 1 month
Revision Date:
2026-04-27
Analytical Information
| Tests | Specifications |
|---|---|
| Description | Leptomycin B (CI 940; LMB (LMB) is a protein exit nuclear transport inhibitor. Leptomycin deactivates CRM1/exportin 1 by covalent modification at cysteine residues. Leptomycin B is a potent antifungal antibiotic that blocks the eukaryotic cell cycle. |
| Native Source | Streptomyces sp. |
| Form | Liquid |
| Color | White to off-white |
| Purity (HPLC) | 99% |
| Solubility | Supplied in solution in ethanol (1 mg/ml). Further dilutions may be made with either ethanol or DMSO. |
| ¹H NMR | Pass test |
Disclaimer: This information relates only to the specific material designated and may not be valid for such material used in combination with anyother materials or in any other process. Such information is to be the best of the company's knowledge and believed accurate and reliable as of thedate indicated. However, no representation, warranty or guarantee of any kind, express or implied, is made as to its accuracy, reliability orcompleteness and we assume no responsibility for any loss, damage or expense, direct or consequential, arising out of use. It is the user'sresponsibility to satisfy himself as to the suitableness & completeness of such information for his own particular use.
ChemicalBook