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Technical Data Sheet LY2109761
Compound Information
Product Name:
LY2109761
CAS No.:
700874-71-1
Molecular Formula:
C26H27N5O2
Molecular Weight:
441.52
Storage:
Store at -20°C
Revision Date:
2026-04-27
Analytical Information
| Tests | Specifications |
|---|---|
| Description | LY2109761 is a novel TGF-β receptor type I and type II dual inhibitor, with Ki values of 38 nM and 300 nM, respectively. |
| IUPAC Name | 4- [5,6- Dihydro- 2- (2- pyridinyl)- 4H- pyrrolo[1,2- b]pyrazol- 3- yl]- 7- [2- (4- morpholinyl)ethoxy]quinoline |
| Form | solid |
| Color | White to yellow |
| Solubility | ≥22.1 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH |
| HPLC | Shows 98.5% purity |
| Identification (Mass Spectrometry - APCI) | MH+: 442.5 |
| Melting Point | 172 - 182 °C |
| λmax | 236 nm |
| NMR | Pass test |
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