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Technical Data Sheet Nicotine

Compound Information
Product Name: Nicotine
CAS No.: 54-11-5
Molecular Formula: C10H14N2
Molecular Weight: 162.23
Storage: Store at RT
Revision Date: 2026-04-15
Analytical Information
Tests Specifications
Appearance Colorless or brownish viscous liquid, volatile
Water Content (Karl Fisher) ≤ 0.5%
Specific Rotation [a]25D = -130 to -143 °
Related Substances Nicotine related compound A, B, C, D, E, F, G : ≤ 0.3% each; Any other unspecified impurity : ≤ 0.1%; Total impurity : ≤ 0.8%
Assay by titration 99 - 101% (Potentiometry)
Specification Reference USP
Identification B To pass test
Tobacco Specific Nitrosamines (TSNAs) 1) NNN [(2S)-N'-Nitrosonornicotine] : ≤ 0.5 ppm; 2) NNK [4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone] : ≤ 0.5 ppm
MS Pass test
¹H NMR Pass test
¹³C NMR Pass test
IR Pass test
Raman Pass test
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