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Technical Data Sheet NS-018
Compound Information
Product Name:
NS-018
CAS No.:
1239358-86-1
Molecular Formula:
C21H20FN7
Molecular Weight:
389.43
Storage:
Powder -20°C 3 years; 4°C 2 years
In solvent -80°C 6 months; -20°C 1 month
In solvent -80°C 6 months; -20°C 1 month
Revision Date:
2026-04-15
Analytical Information
| Tests | Specifications |
|---|---|
| Description | Ilginatinib (NS-018) is a highly active and orally bioavailable JAK2 inhibitor, with an IC50 of 0.72 nM, 46-, 54-, and 31-fold selectivity for JAK2 over JAK1 (IC50, 33 nM), JAK3 (IC50, 39 nM), and Tyk2 (IC50, 22 nM). |
| Form | Solid |
| Solubility | DMSO : ≥ 34 mg/mL (87.31 mM) |
| ¹H NMR | Pass test |
Disclaimer: This information relates only to the specific material designated and may not be valid for such material used in combination with anyother materials or in any other process. Such information is to be the best of the company's knowledge and believed accurate and reliable as of thedate indicated. However, no representation, warranty or guarantee of any kind, express or implied, is made as to its accuracy, reliability orcompleteness and we assume no responsibility for any loss, damage or expense, direct or consequential, arising out of use. It is the user'sresponsibility to satisfy himself as to the suitableness & completeness of such information for his own particular use.
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