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Technical Data Sheet Sivelestat sodium
Compound Information
Product Name:
Sivelestat sodium
CAS No.:
201677-61-4
Molecular Formula:
C20H25N2NaO8S
Molecular Weight:
476.48
Storage:
Powder -20°C 3 years; 4°C 2 years
In solvent -80°C 6 months; -20°C 1 month
In solvent -80°C 6 months; -20°C 1 month
Revision Date:
2026-04-15
Analytical Information
| Tests | Specifications |
|---|---|
| Description | Sivelestat sodium tetrahydrate is a competitive inhibitor of human neutrophil elastase, with an IC50 of 44 nM and a Ki of 200 nM. Sivelestat (EI546) sodium tetrahydrate also inhibits leukocyte elastase obtained from rabbit, rat, hamster and mouse. |
| Form | White solid. |
| Color | White |
| Solubility | Soluble in DMSO (up to 20 mg/ml). |
| Purity | 99.62% |
| ¹H NMR | Pass test |
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