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Technical Data Sheet TM 5275

Compound Information
Product Name: TM 5275
CAS No.: 1103926-82-4
Molecular Formula: C28H29ClN3NaO5
Molecular Weight: 546
Storage: Store at +4°C
Revision Date: 2026-04-27
Analytical Information
Tests Specifications
Description TM5275 sodium is an orally available, potent and selective plasminogen activator inhibitor (PAI-1) with an IC50 of 6.95 μM that delivers antithrombotic benefits devoid of bleeding effect in nonhuman primates.
IUPAC Name 5-Chloro-2-[[2-[2-[4-(Diphenylmethyl)-1-piperazinyl]-2-oxoethoxy]acetyl]amino]benzoic acid sodium salt
Form powder
Color white to beige
Solubility DMSO:20.0(Max Conc. mg/mL);36.77(Max Conc. mM)
DMF:PBS (pH 7.2) (1:8):0.11(Max Conc. mg/mL);0.2(Max Conc. mM)
DMF:33.0(Max Conc. mg/mL);60.66(Max Conc. mM)
HPLC Shows 99% purity
¹H NMR Pass test
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