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Technical Data Sheet TPPB
Compound Information
Product Name:
TPPB
CAS No.:
497259-23-1
Molecular Formula:
C27H30F3N3O3
Molecular Weight:
501.54
Storage:
Store at -20°C
Revision Date:
2026-04-27
Analytical Information
| Tests | Specifications |
|---|---|
| Description | A cell-permeable benzolactam derived PKC activator (Ki = 11.9 nM for PKCα) that efficiently enhances non-amyloidogenic α-processing of amyloid precursor protein (APP) even at 100 nM in human fibroblast AG06848. Displays a marked loss of tumor promoting ac |
| IUPAC Name | (2E,4E)- N- [(2S,5S)- 1,2,3,4,5,6- Hexahydro- 5- (hydroxymethyl)- 1- methyl- 2- (1- methylethyl)- 3- oxo- 1,4- benzodiazocin- 8- yl]- 5- [4- (trifluoromethyl)phenyl]- 2,4- pentadienamide |
| Form | Solid |
| Color | Light yellow to yellow |
| Solubility | 25.08mg/mL in DMSO |
| HPLC | Shows 99.4% purity |
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