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Technical Data Sheet Trimethoprim
Compound Information
Product Name:
Trimethoprim
CAS No.:
738-70-5
Molecular Formula:
C14H18N4O3
Molecular Weight:
290.32
Revision Date:
2026-04-15
Analytical Information
| Tests | Specifications |
|---|---|
| Appearance | White or yellowish-white powder |
| Purity | 98.5 - 101.0% |
| Melting Point | 199-203 °C |
| Residual Solvents | Methanol ≤ 3000 ppm; DMSO ≤ 5000 ppm; Acetic acid ≤ 5000 ppm |
| Solubility | DMSO: soluble |
| Solution | Not more intensely colored than reference Solution BY₇ |
| Total Impurities (HPLC) | ≤ 0.2% |
| Absorbance | Max. 287 nm: 240 - 250 |
| Fluorescence | Green fluorescence at 365 nm |
| Heavy Metals | ≤ 20 ppm |
| Impurity | Impurity F ≤ 0.1%; Impurity K (aniline by GC) ≤ 5 ppm |
| Loss on Drying | ≤ 1.0% |
| Single Impurity | ≤ 0.1% |
| Sulfated Ash | ≤ 0.1% |
| MS | Pass test |
| ¹H NMR | Pass test |
| ¹³C NMR | Pass test |
| IR | Pass test |
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