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Technical Data Sheet Vatalanib base
Compound Information
Product Name:
Vatalanib base
CAS No.:
212141-54-3
Molecular Formula:
C20H15ClN4
Molecular Weight:
346.81
Storage:
Store the product in sealed, cool and dry condition.
Revision Date:
2026-04-27
Analytical Information
| Tests | Specifications |
|---|---|
| Description | Vatalanib is an inhibitor of the VEGFR tyrosine kinases VEGFR-1 (Flt-1, IC₅₀ = 77 nM) and VEGFR-2 (FLK-1/KDR, IC₅₀ = 37 nM), with slightly higher potency against the latter. |
| Form | solid |
| Color | Light yellow to yellow |
| Purity | >98% |
| General tips | For obtaining a higher solubility, please warm the tube at 37 degrees Celsius (98.6 degrees Fahrenheit) and shake it in the ultrasonic bath for a while. |
| Melting Point | 206-210 °C |
| Solubility | DMSO 25 mg/mL |
| NMR | Pass test |
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