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1304630-27-0

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1304630-27-0 Structure

1304630-27-0 Structure
IdentificationBack Directory
[Name]

NGP 555
[CAS]

1304630-27-0
[Synonyms]

NGP 555
N-(5-ethyl-2,4-dimethylphenyl)-4-(3-fluoro-4-(4-methyl-1H-imidazol-1-yl)phenyl)thiazol-2-amine
2-Thiazolamine, N-(5-ethyl-2,4-dimethylphenyl)-4-[3-fluoro-4-(4-methyl-1H-imidazol-1-yl)phenyl]-
[Molecular Formula]

C23H23FN4S
[MOL File]

1304630-27-0.mol
[Molecular Weight]

406.52
Chemical PropertiesBack Directory
[Boiling point ]

574.9±60.0 °C(Predicted)
[density ]

1.24±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO: soluble
[form ]

A solid
[pka]

5.16±0.61(Predicted)
Hazard InformationBack Directory
[Uses]

NGP555, is a γ-secretase modulator. It significantly lowers Aβ42 in cell cultures. it also has shown good oral bioavailability and is brain-penetrant.
[storage]

Store at -20°C
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