| Identification | More | [Name]
8-Hydroxyquinoline sulfate | [CAS]
134-31-6 | [Synonyms]
8-HYDROXY-1-AZANAPHTHALENE HEMISULFATE SALT
8-HYDROXYL QUINOLINE SULFATE
8-HYDROXYQUINOLINE HEMISULFATE SALT
8-HYDROXYQUINOLINE SULFATE
8-HYDROXYQUINOLINE SULPHATE
8-HYDROXYQUINOLINIUM SULFATE
8-QUINOLINOL HEMISULFATE SALT
8-QUINOLINOL SULFATE
8-quinolinol sulfate (2:1)
8-QUINOLINOL SULPHATE
8-QUINOLINONE SULFATE
bis(8-hydroxyquinolinium) sulphate
CHINOSOL
HYDROXYQUINOLINE SULFATE
OXINE SULFATE
OXYQUINOLINE SULFATE
QUINOSOL
8-hydroxy-chinolin-sulfat
8-Hydroxyquinolinesulfuricacidsalt
8-Quinolinol,hydrogensulfate(2:1) | [EINECS(EC#)]
205-137-1 | [Molecular Formula]
C9H9NO5S | [MDL Number]
MFCD00013095 | [Molecular Weight]
243.24 | [MOL File]
134-31-6.mol |
| Chemical Properties | Back Directory | [Appearance]
Crystalline | [Melting point ]
~175 °C
| [density ]
1.3819 (rough estimate) | [vapor pressure ]
0Pa at 25℃ | [refractive index ]
1.5364 (estimate) | [storage temp. ]
Inert atmosphere,Room Temperature | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
crystalline
| [color ]
yellow
| [Water Solubility ]
>=10 g/100 mL at 19 ºC | [Merck ]
4843 | [BRN ]
3760550 | [InChIKey]
MRUMAIRJPMUAPZ-UHFFFAOYSA-N | [LogP]
2.42 at 25℃ | [Uses]
oxyquinoline sulfate is a disinfectant and a preservative against fungus growth. It is made from phenols. | [CAS DataBase Reference]
134-31-6(CAS DataBase Reference) | [EPA Substance Registry System]
134-31-6(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R22:Harmful if swallowed. | [Safety Statements ]
S36:Wear suitable protective clothing . | [RIDADR ]
2811 | [WGK Germany ]
1
| [RTECS ]
VC8260000
| [F ]
3-10 | [HazardClass ]
6.1(b) | [PackingGroup ]
III | [HS Code ]
29339900 |
| Hazard Information | Back Directory | [General Description]
Pale yellow to yellow crystalline powder with a slight saffron odor. Burning taste. | [Reactivity Profile]
A sulfate acidic salt of an amine that is also a phenol. Materials in this group are generally soluble in water. The resulting solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible. Many of these compounds catalyze organic reactions. | [Air & Water Reactions]
Water soluble. | [Fire Hazard]
Flash point data for this chemical are not available, but 8-HYDROXYQUINOLINE SULFATE is probably combustible. | [Chemical Properties]
Crystalline | [Originator]
Chinosol,Chinosolfabrik | [Manufacturing Process]
The mixture of 1.4 kg o-nitrophenol, 2.1 kg o-aminophenol, 6 kg glycerine (d = 1.26) and 5 kg sulfuric acid (d = 1.848) was heated at reflux to temperature 130°-140°C. This temperature was kept for 1.5 hours. The obtained oxyquinoline precipitated, the liquid was removed with water-steam distillation. The residue was diluted with water and alkalized with sodium hydroxide and sodium carbonate to the strong alkaline reaction. The repeated distillation with water steam gave the oil, which hardened as the long needles by cooling. MP: 75°-76°C recrystallized from diluted ethanol.
In practice it is usually used as sulfate salt | [Therapeutic Function]
Antiseptic | [Flammability and Explosibility]
Notclassified | [Metabolic pathway]
Little published information is available. | [Degradation]
The salt and free base of 8-hydroxyquinoline sulfate are very stable
but alkali liberates quinolin-8-ol which precipitates heavy metals (PM).
8-Hydroxyquinoline is a chelate ligand of transition metals such as
copper. |
|
|