| Identification | More | [Name]
Carboprost | [CAS]
35700-23-3 | [Synonyms]
15-methyl prostaglandin f2alpha
15(S)-15-METHYL PROSTAGLANDIN F2ALPHA
9ALPHA,11ALPHA,15S-TRIHYDROXY-15-METHYL-PROSTA-5Z,13E-DIEN-1-OIC ACID
CARBOPROST
U-32921
(z)-7-[(3r,5s)-3,5-dihydroxy-2-[(e,3s)-3-hydroxy-3-methyl-oct-1-enyl]cyclopentyl]hept-5-enoic acid
(5z,9-alpha,11-alpha,13e,15s)-9,11,15-trihydroxy-15-methylprosta-5,13-dien-1
15(s)-15-methylpgf2-alpha
15(s)-methylprostaglandinf2-alpha
15-me-pgf2-alpha
15-methyl-pgf2alpha
15-methylpgf2-alpha
15s)-13e
methyl-pgf2-alpha
-oicacid
prosta-5,13-dien-1-oicacid,9,11,15-trihydroxy-15-methyl-,(5z,9-alpha,11-alph
prostin15m
15(S)-15-methylProstaglandinF2a
(15S)-15-Methyl-PGF2a
(5Z,9a,11a,13E,15S)-9,11,15-Trihydroxy-15-methylprosta-5,13-dien-1-oic Acid | [Molecular Formula]
C21H36O5 | [MDL Number]
MFCD00135249 | [Molecular Weight]
368.51 | [MOL File]
35700-23-3.mol |
| Chemical Properties | Back Directory | [Melting point ]
79-82°C | [Boiling point ]
418.83°C (rough estimate) | [density ]
1.0390 (rough estimate) | [refractive index ]
1.6120 (estimate) | [storage temp. ]
-20°C Freezer, Under Inert Atmosphere | [solubility ]
10 mM Na2CO3: >6.5 mg/ml (from PGF2a); DMF: >100 mg/ml (from PGF2a); DMSO: >100 mg/ml (from PGF2a); Ethanol: >100 mg/ml (from PGF2a); PBS pH 7.2: >10 mg/ml (from PGF2a) | [form ]
Solid | [pka]
4.76±0.10(Predicted) | [color ]
White | [Usage]
Analog of prostaglandin F2a. Oxytocic | [CAS DataBase Reference]
35700-23-3(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Description]
15(S)-15-methyl PGF2α is a metabolically stable analog of PGF2α. It is a potent uterine stimulant and abortifacient which can be administered intramuscularly to induce labor.1,2,3 It induces luteolysis and reduces serum progesterone concentrations when given as an intramuscular injection in non-pregnant rhesus monkeys.4 | [Chemical Properties]
Off- White Solid | [Uses]
Analog of prostaglandin F2a. Oxytocic | [Uses]
Analog of prostaglandin F2α. Oxytocic. | [Definition]
ChEBI: Prostaglandin F2alpha in which the hydrogen at position 15 is substituted by methyl (S configuration). It is used as an abortifacient agent that is effective in both the first and second trimesters of
regnancy. | [Brand name]
Hemabate (Pharmacia & Upjohn). |
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