| Identification | More | [Name]
Alantolactone | [CAS]
546-43-0 | [Synonyms]
[3ar-(3aa,5b,8ab,9aa)]-3a,5,6,7,8,8a,9,9a-octahydro-5,8a-dimethyl-3-methylenenaphtho-[2,3-b]furan-2(3h)-one
8b-hydroxy-4ah-eudesm-5-en-12-oic acid
ALANTOLACETONE
ALANTOLACTONE
ALLANTOLACTONE
HELENINE
[3aR-(3aalpha,5beta,8abeta,9aalpha)]-3a,5,6,7,8,8a,9,9a-octahydro-5,8a-dimethyl-3-methylenenaphtho[2,3-b]furan-2(3H)-one
Alantolactone (Helenin)
helenin
4αH-Eudesma-5,11(13)-dien-12-oic acid, 8β-hydroxy-, γ-lactone (8CI)
Alant camphor
Alantolactone (6CI)
Elecampane camphor
Eupatal
Helenin (7CI)
Inula camphor
Naphtho[2,3-b]furan-2(3H)-one, 3a,5,6,7,8,8a,9,9a-octahydro-5,8a-dimethyl-3-methylene-, (3aR,5S,8aR,9aR)-
Naphtho[2,3-b]furan-2(3H)-one, 3a,5,6,7,8,8a,9,9a-octahydro-5,8a-dimethyl-3-methylene-, [3aR-(3aα,5β,8aβ,9aα)]-
NSC 93131
[3aR-(3aa,5b,8ab,9aa)]-3a,5,6,7,8,8a,9,9a-Octahydro-5,8a-dimethyl-3-methylenenaphtho-[2,3-b]furan-2(3H)-one | [EINECS(EC#)]
208-899-3 | [Molecular Formula]
C3H5NO2 | [MDL Number]
MFCD00046915 | [Molecular Weight]
87.08 | [MOL File]
546-43-0.mol |
| Chemical Properties | Back Directory | [Melting point ]
78-79 C | [alpha ]
D +175° (chloroform) | [Boiling point ]
275 C | [density ]
1.0610 (rough estimate) | [refractive index ]
1.4360 (estimate) | [storage temp. ]
?20°C | [solubility ]
DMSO: soluble15mg/mL (clear solution) | [form ]
powder | [color ]
white to beige | [Contact allergens]
The allergen eudesmanolide sesquiterpene lactone was
isolated from elecampane (Inula helenium L.). With
dehydrocostuslactone and costunolide, it is a component
of the (sesquiterpene) lactone mix used to detect
sensitization to Compositae-Asteraceae. | [LogP]
3.380 | [CAS DataBase Reference]
546-43-0(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Chemical Properties]
Crystalline powder | [Uses]
Alantolactone is sesquiterpene lactone that possesses anti-inflammatory property. Alantolactone have been studied to be developed as a novel agent against human liver cancer. | [Uses]
anthelmintic, antibacterial, antineoplastic | [Definition]
ChEBI: A sesquiterpene lactone that is 3a,5,6,7,8,8a,9,9a-octahydronaphtho[2,3-b]furan-2-one bearing two methyl substituents at positions 5 and 8a as well as a methylidene substituent at position 3. | [Description]
The allergen eudesmanolide sesquiterpene lactone was
isolated from elecampane (Inula helenium L.). With
dehydrocostuslactone and costunolide, it is a component
of the (sesquiterpene) lactone-mix, used to detect
sensitization to Compositae.
| [General Description]
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG | [Biochem/physiol Actions]
Alantolactone is a sesquiterpene lactone disrupts the Cripto-1/ActRII complexes, resulting in an induction of activin/SMAD3 signaling. Alantolactone inhibits proliferation in cancer cells with no affect on normal cells. | [storage]
Store at -20°C |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3 | [HS Code ]
29322090 |
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