| Identification | More | [Name]
2-Chloroquinoline | [CAS]
612-62-4 | [Synonyms]
2-CHLOROQUINOLINE
2CQ
2-chloro-quinolin
Quinoline2-chloro-
2-Chloroquinoline,99% | [EINECS(EC#)]
210-317-8 | [Molecular Formula]
C9H6ClN | [MDL Number]
MFCD00006741 | [Molecular Weight]
163.6 | [MOL File]
612-62-4.mol |
| Chemical Properties | Back Directory | [Appearance]
white to yellowish crystals, powder, chunks or | [Melting point ]
34-37 °C (lit.) | [Boiling point ]
266-267 °C (lit.) | [density ]
1.23 g/mL at 25 °C(lit.)
| [refractive index ]
1.6342 (estimate) | [Fp ]
>230 °F
| [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [solubility ]
methanol: 0.1 g/mL, clear
| [form ]
Crystalline Powder, Crystals and/or Chunks or Fused Mass | [pka]
0.41±0.40(Predicted) | [color ]
White to yellow | [Water Solubility ]
Insoluble | [BRN ]
112561 | [InChIKey]
OFUFXTHGZWIDDB-UHFFFAOYSA-N | [CAS DataBase Reference]
612-62-4(CAS DataBase Reference) | [NIST Chemistry Reference]
Quinoline, 2-chloro-(612-62-4) | [EPA Substance Registry System]
612-62-4(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [RTECS ]
VB2320000
| [F ]
8 | [TSCA ]
Yes | [HS Code ]
29334900 |
| Hazard Information | Back Directory | [Chemical Properties]
white to yellowish crystals, powder, chunks or | [Uses]
2-Chloroquinoline is an intermediate used in the synthesis of various compounds that exhibits antifungal properties. | [Synthesis Reference(s)]
The Journal of Organic Chemistry, 67, p. 7884, 2002 DOI: 10.1021/jo016196i
Synthesis, p. 1013, 1987 DOI: 10.1055/s-1987-28152 | [Purification Methods]
Purify it by crystallisation of its picrate to constant melting point (123-124o) from *benzene, regenerating the base and distilling it under vacuum [Cumper et al. J Chem Soc 1183 1962]. 2-Chloroquinoline can be crystallised from EtOH. Its picrate has m 123-124o (from EtOH). [Beilstein 20 H 359, 20/7 V 312.] |
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