| Identification | More | [Name]
Menatetrenone | [CAS]
863-61-6 | [Synonyms]
MENAQUINONE
MENAQUINONE 4
MENATETRENONE
VITAMIN K2
1,4-naphthoquinone,2-methyl-3-(3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraen
2-methyl-3-(3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraenyl)-1,4-naphthoqu
2-methyl-3-trans-tetraprenyl-1,4-naphthoquinone
e3100
k2(sub20)
kaytwo
menaquinonek(sub4)
mk(sub4)
vitamink2(sub20)
MENAQUINONE (K2) 100MG NEAT
VitaminK2(20)0.13%Oil
VitaminK2(45)98.0%Min.Powder
VitaminK2(20)
VitaminK2(20)1.3%Powder
VitaminK2(20)98.0%Oil
VitaminK2(20)98.0%Powder | [Molecular Formula]
C31H40O2 | [MDL Number]
MFCD00079646 | [Molecular Weight]
444.65 | [MOL File]
863-61-6.mol |
| Chemical Properties | Back Directory | [Appearance]
Yellow Crystals | [Melting point ]
350C | [Boiling point ]
494.59°C (rough estimate) | [density ]
1.0461 (rough estimate) | [refractive index ]
1.5045 (estimate) | [Fp ]
2℃ | [storage temp. ]
−20°C
| [solubility ]
Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly, Heated) | [form ]
neat | [color ]
Light Yellow to Yellow | [Usage]
Vitamin (prothrombogenic) | [InChIKey]
DKHGMERMDICWDU-GHDNBGIDSA-N | [CAS DataBase Reference]
863-61-6(CAS DataBase Reference) |
| Safety Data | Back Directory | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes . | [RIDADR ]
UN 1648 3 / PGII | [WGK Germany ]
3
| [RTECS ]
QL9279500
| [HS Code ]
2914699000 | [Toxicity]
LD50 intravenous in dog: > 40mL/kg |
| Hazard Information | Back Directory | [Description]
Menatetrenone (also known as MK-4) is a manaquinone compound and a vitamin K compound which can be used as a hemostatic agent as well as adjunctive therapy for the pain of osteoporosis. It mainly takes effects through modulating the signaling of certain tyrosine kinases, thereby affecting several transcription factors including c-myc and c-fos. It is capable of inhibiting tumor cells growth through inducing apoptosis and cell cycle arrest. It can be produced via the conversion of vitamin K1 inside the body including the testes, pancreas and arterial walls. | [Chemical Properties]
Yellow Crystals | [Occurrence]
Menatetrenone (vitamin K2) is widely found in green leaves and vegetables, and also in fish, meat, cheese and liver oil. | [Uses]
Menaquinones are isoprenoid quinones of the naphthalene series and belongs to the K2 Vitamin homologs. Menaquinones were originally discovered as the anti-hemorrhagic factor and now encompasses a vari
ety of physiological processes. Menaquinone 4 has four isoprene residue in its side chain and is also commonly refered to as menatetrenone. Menaquinone-4 is the most common type of vitamin K2 and is k
nown as a hemostatic agent and is used as adjunctive therapy for the pain of osteoporosis. | [Uses]
Vitamin (prothrombogenic) | [Definition]
ChEBI: A menaquinone whose side-chain contains 4 isoprene units in an all-trans-configuration. | [Preparation]
It can be extracted from millet leaves and rotten fish, and can also be synthesized with 2-menaquinone-1,4. | [General Description]
Menaquinone (K2), a vitamin K2 homologue with four isoprene units. It has been reported to enhance bone formation and plays a vital role in the production of blood coagulation factors. | [Biochem/physiol Actions]
Menatetrenone (MK-4) is one of nine forms of vitamin K2 which is ubiquitously present in extrahepatic tissues. MK-4 has a number of metabolic and anti-neoplastic activities. | [storage]
4°C, protect from light | [References]
https://pubchem.ncbi.nlm.nih.gov/compound/menatetrenone#section=Biomolecular-Interactions-and-Pathways
https://en.wikipedia.org/wiki/Menatetrenone |
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