蛇孢菌素A
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- CAS号:
- 4611-05-6
- 英文名:
- OPHIOBOLIN A
- 英文别名:
- ophiobolin;cochliobolin;OPHIOBOLIN A;COCHLIOBOLIN A;Ophiobolin A >=95% (HPLC);Ophiobolin A (Cochliobolin A);Ophiobolin, Helminthosporium sp.;Cochliobolin A, Ophiobolin, Ophiobalin;ophiobolin A from helminthosporium sp.;18-epoxy-3-hydroxy-5-oxo-19-dien-25-a(18r)-ophiobola-14
- 中文名:
- 蛇孢菌素A
- 中文别名:
- 蛇孢菌素;蛇孢菌素A
- CBNumber:
- CB2735485
- 分子式:
- C25H36O4
- 分子量:
- 400.55
- MOL File:
- 4611-05-6.mol
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蛇孢菌素A化学性质
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熔点:
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182°C
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沸点:
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443.19°C (rough estimate)
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密度:
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1.0278 (rough estimate)
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折射率:
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1.4460 (estimate)
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储存条件:
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2-8°C
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溶解度:
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Soluble in DMSO (up to 10 mg/ml)
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形态:
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White to off-white solid.
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酸度系数(pKa):
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13.84±0.70(Predicted)
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颜色:
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White
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稳定性:
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Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
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蛇孢菌素A性质、用途与生产工艺
蛇孢菌素A(OphA)是一种由双极霉属真菌产生的二倍半萜化合物，已被证实在多种实体瘤中具有抗癌效应，但其在直肠癌中的作用尚不明确。
Ophiobolin A 是一种真菌代谢产物和植物毒素，是一种有效的、不可逆的钙调素激活环核苷酸磷酸二酯酶的抑制剂，其IC50 值为 9 μM。Ophiobolin A 具有抗菌和抗癌作用。
IC50: 9 μM (calmodulin-activated cyclic nucleotide phosphodiesterase).
蛇孢菌素A
上下游产品信息
上游原料
下游产品
4611-05-6, 蛇孢菌素A 相关搜索:
- 药靶配体
- 化工原料
- 微生物代谢物
- Intracellular Calcium Signaling
- BioChemical
- Cell Biology
- Calcium Antagonists
- Cell Signaling and Neuroscience
- C25H36O4
- 蛇孢菌素
- 蛇孢菌素A
- 4611-05-6
- Ophiobolin A (Cochliobolin A)
- Ophiobolin A >=95% (HPLC)
- Spiro[dicyclopenta[a,d]cyclooctene-3(2H),2'(3'H)-furan]-6-carboxaldehyde, 1,3a,4,4',5',6a,7,8,9,9a,10,10a-dodecahydro-9-hydroxy-3',9,10a-trimethyl-5'-(2-methyl-1-propen-1-yl)-7-oxo-, (2'S,3'S,3aR,5'R,6aS,9R,9aS,10aR)-
- OPHIOBOLIN A
- Cochliobolin A, Ophiobolin, Ophiobalin
- (18R)-3-Hydroxy-5-oxo-14,18-epoxyophiobola-7,19-diene-25-al
- (18R)-14,18-Epoxy-3-hydroxy-5-oxoophiobola-7,19-dien-25-al
- Ophiobolin, Helminthosporium sp.
- ophiobolin A from helminthosporium sp.
- COCHLIOBOLIN A
- ophiobolin
- cochliobolin
- 18-epoxy-3-hydroxy-5-oxo-19-dien-25-a(18r)-ophiobola-14