1208222-39-2
|
|
|
- CAS号:
- 1208222-39-2
- 英文名:
- VU 0365114
- 英文别名:
- VU 0365114;1-Biphenyl-4-ylmethyl-5-trifluoromethoxy-1H-indole-2,3-dione;1-([1,1'-Biphenyl]-4-ylmethyl)-5-(trifluoromethoxy)indoline-2,3-dione;1-[(1,1'-Biphenyl)-4-ylmethyl]-5-(trifluoromethoxy)-1H-indole-2,3-dione;1H-Indole-2,3-dione, 1-([1,1'-biphenyl]-4-ylmethyl)-5-(trifluoromethoxy)-;VU 0365114,inhibit,Muscarinic acetylcholine receptor,VU0365114,Inhibitor,VU-0365114,mAChR
- 中文名:
- 1208222-39-2
- 中文别名:
- 化合物VU 0365114;VU 0365114,M5受体的正变构调节剂;1-([1,1'-联苯]-4-基甲基)-5-(三氟甲氧基)二氢吲哚-2,3-二酮;1-([1,1'-联苯]-4-基甲基)-5-(三氟甲氧基)二氢吲哚-2,3-二酮
- CBNumber:
- CB32652655
- 分子式:
- C22H14F3NO3
- 分子量:
- 397.35
- MOL File:
- 1208222-39-2.mol
|
|
|
1208222-39-2化学性质
-
沸点:
-
526.2±60.0 °C(Predicted)
-
|
-
密度:
-
1.386±0.06 g/cm3(Predicted)
-
|
-
储存条件:
-
2-8°C
-
|
-
溶解度:
-
Ethanol:10.0(Max Conc. mg/mL);25.17(Max Conc. mM)
DMSO:30.0(Max Conc. mg/mL);75.5(Max Conc. mM)
DMF:30.0(Max Conc. mg/mL);75.5(Max Conc. mM)-
|
-
形态:
-
Powder
-
|
-
酸度系数(pKa):
-
-3.71±0.20(Predicted)
-
|
1208222-39-2性质、用途与生产工艺
VU 0365114 是 mAChR M5 的正变构调节剂，其EC50 值为2.7 μM。
EC50: 2.7 μM (mAChR M
5
).
用途
VU 0365114 is a selective positive allosteric modulator of M5 (EC50 values are 2.7 μM for human M5, and >30 μM for M1, M2, M3 and M4 receptors).
1208222-39-2
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/04/30 | HY-107651 | VU 0365114 | | 1 mg | 400元 |
| 2024/04/30 | HY-107651 | 1208222-39-2
VU 0365114 | 1208222-39-2 | 5mg | 900元 |
1208222-39-2, 1208222-39-2 相关搜索:
- Intermediates & Fine Chemicals
- Heterocycles
- Aromatics
- Amines
- Pharmaceuticals
- 药靶配体
- 1-([1,1'-联苯]-4-基甲基)-5-(三氟甲氧基)二氢吲哚-2,3-二酮
- VU 0365114,M5受体的正变构调节剂
- 化合物VU 0365114
- 1-([1,1'-联苯]-4-基甲基)-5-(三氟甲氧基)二氢吲哚-2,3-二酮
- 1208222-39-2
- 1-([1,1'-Biphenyl]-4-ylmethyl)-5-(trifluoromethoxy)indoline-2,3-dione
- VU 0365114,inhibit,Muscarinic acetylcholine receptor,VU0365114,Inhibitor,VU-0365114,mAChR
- 1H-Indole-2,3-dione, 1-([1,1'-biphenyl]-4-ylmethyl)-5-(trifluoromethoxy)-
- 1-[(1,1'-Biphenyl)-4-ylmethyl]-5-(trifluoromethoxy)-1H-indole-2,3-dione
- 1-Biphenyl-4-ylmethyl-5-trifluoromethoxy-1H-indole-2,3-dione
- VU 0365114