N-Me-phe（3）-吗啡肽
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- CAS号:
- 83397-56-2
- 英文名:
- PL017
- 英文别名:
- PL017;TYR-PRO-(NME)PHE-DPRO-NH2;morphiceptin, N-Me-Phe(3)-;[NMPhe3,D-Pro4]morphiceptin;H-TYR-PRO-N-ME-PHE-D-PRO-NH2;[N-ME-PHE3, D-PRO4]-MORPHICEPTIN;L-Tyr-L-Pro-N-Methyl-L-Phe-D-Pro-NH2;[(NME)PHE3, DPRO4] MORPHICEPTIN, BOVINE;[NMePhe3, DPro4] b-Casomorphin: 1-4, amide, bovine;{N-METHYL-PHE3,D-PRO4}-BETA-CASOMORPHIN FRAGMENT 1-
- 中文名:
- N-Me-phe（3）-吗啡肽
- 中文别名:
- N-ME-PHE(3)-吗啡肽;H-TYR-PRO-N-ME-PHE-PRO-NH2
- CBNumber:
- CB5131318
- 分子式:
- C29H37N5O5
- 分子量:
- 535.63
- MOL File:
- 83397-56-2.mol
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N-Me-phe（3）-吗啡肽化学性质
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沸点:
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878.5±65.0 °C(Predicted)
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密度:
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1.313±0.06 g/cm3(Predicted)
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储存条件:
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−20°C
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形态:
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Powder
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酸度系数(pKa):
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9.86±0.15(Predicted)
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水溶解性:
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Soluble to 1 mg/ml in water
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N-Me-phe（3）-吗啡肽性质、用途与生产工艺
PL-017 是一种有效的，选择性 μ 阿片受体 (μ opioid receptor) 激动剂，对 125I-FK 33,824 与 μ 位点结合的 IC50 为 5.5 nM。PL-017 在大鼠中产生持久的可逆性镇痛作用。
IC50: 5.5 nM (
125
I-FK 33,824 binding to μ site)
PL-017 has an IC
50
of 10000 nM for
125
I-DADLE binding to δ site.
PL-017 (0.22, 0.45, 0.9 nmol/rat; i.c.v.) has the time of maximum effect of approximately 15 to 30 mm after injection at lower doses and produces analgesia lasting as long as 4 hours with larger doses in male Sprague-Dawley rats weighing 250 to 375 g.
N-Me-phe（3）-吗啡肽
上下游产品信息
上游原料
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83397-56-2, N-Me-phe（3）-吗啡肽 相关搜索:
- 多肽
- 标准品
- Other Peptides
- Peptides
- BioChemical
- Biochemicals and Reagents
- Amino Acids and Peptides
- C29H37N5O5
- H-TYR-PRO-N-ME-PHE-PRO-NH2
- N-ME-PHE(3)-吗啡肽
- 83397-56-2
- D-Prolinamide, L-tyrosyl-L-prolyl-N-methyl-L-phenylalanyl-
- (N-Me-Phe3,D-Pro4)-β-Casomorphin (1-4) amide (bovine)
- [NMePhe3, DPro4] b-Casomorphin: 1-4, amide, bovine
- L-Tyr-L-Pro-N-Methyl-L-Phe-D-Pro-NH2
- [NMPhe3,D-Pro4]morphiceptin
- morphiceptin, N-Me-Phe(3)-
- [n-methyl-phe3, d-pro4]-β-casomorphin fragment 1-4 amide, bovine
- {N-METHYL-PHE3,D-PRO4}-BETA-CASOMORPHIN FRAGMENT 1-
- H-TYR-PRO-N-ME-PHE-D-PRO-NH2
- TYR-PRO-(NME)PHE-DPRO-NH2
- PL017
- [(NME)PHE3, DPRO4] MORPHICEPTIN, BOVINE
- [N-ME-PHE3, D-PRO4]-MORPHICEPTIN
- (N-ME-PHE3,D-PRO4)-BETA-CASOMORPHIN (1-4) AMIDE (BOVINE)