SWAINSONINE
|
|
|
- CAS-Nr.
- 72741-87-8
- Englisch Name:
- SWAINSONINE
- Synonyma:
- 8AR)-1;SwainMoia;Tridolgosir;SWAINSONINE;D-Swainsonine;(-)-Swainsonine;SWAINSONINE 98+%;(-)-D-Swainsonine;Swainsonine min. 99%;swainsonine synthetic
- CBNumber:
- CB0484750
- Summenformel:
- C8H15NO3
- Molgewicht:
- 173.21
- MOL-Datei:
- 72741-87-8.mol
|
SWAINSONINE Eigenschaften
- Schmelzpunkt:
- 148-149°C
- Siedepunkt:
- 353.3±21.0 °C(Predicted)
- Dichte
- 1.38±0.1 g/cm3 (20 ºC 760 Torr)
- storage temp.
- -20°C
- Löslichkeit
- H2O: soluble1mg/mL
- pka
- 14.01±0.60(Predicted)
- Aggregatzustand
- lyophilized powder
- Farbe
- white to faint yellow
- Wasserlöslichkeit
- Soluble to 50 mM in water
- BRN
- 4175740
- Stabilität:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO, ethanol or distilled water may be stored at -20°C for up to 3 months.
- CAS Datenbank
- 72741-87-8
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Kennzeichnung gefährlicher |
Xn |
|
|
| R-Sätze: |
20/21/22 |
|
|
| S-Sätze: |
36 |
|
|
| WGK Germany |
3 |
|
|
| RTECS-Nr. |
NM2408666 |
|
|
| HS Code |
29339900 |
|
|
| Bildanzeige (GHS) |
|
| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
| H312 |
Gesundheitsschädlich bei Hautkontakt. |
Akute Toxizität dermal |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P280,P302+P352, P312, P322, P363,P501 |
| H332 |
Gesundheitsschädlich bei Einatmen. |
Akute Toxizität inhalativ |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P261, P271, P304+P340, P312 |
|
| Sicherheit |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
|
SWAINSONINE Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.
S-Sätze Betriebsanweisung:
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
White Crystalline Solid
Occurrence
Swainsonia canescens yields this simple alkaloid.
Definition
ChEBI: An indolizidine alkaloid isolated from the plant Swainsona canescens with three hydroxy substituents at positions 1, 2 and 8.
Allgemeine Beschreibung
Swainsonine is produced by endophytes, plant and insect pathogens. It is synthesized from the pipecolic acid and mevalonic acid. Swainsonine is a water-soluble indole alkaloid.
Biologische Aktivität
Inhibitor of α -mannosidase II which inhibits glycoprotein processing. Displays anticancer and immune modulatory properties.
SWAINSONINE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
SWAINSONINE Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 164)Lieferanten
72741-87-8()Verwandte Suche:
6-Amino-8-(((aminocarbonyl)oxy)-methyl)-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino-(2',3': 3,4)pyrrolo(1,2-a)indol-4,7-dion,(1aS-(1a alpha, 8 beta, 8a alpha,8b alpha))-
1-Hexanol
Betain
Octacosan-1-ol
- 8-indolizinetriol,octahydro-,(1s,2r,8r,8ar)-2
- (1S,2S,8R,8AR)-TRIHYDROXYINDOLIZIDINE
- (1S,2R,8R,8AR)-1,2,8-OCTAHYDROINDOLIZIDINETRIOL
- 8ALPHA,BETA-INDOLIZIDINE-1,2ALPHA,8BETA-TRIOL
- 8ALPHA,BETA-INDOLIZIDINE-1ALPHA,2ALPHA,8BETA-TRIOL
- 8A-BETA-INDOLIZIDINE-1ALPHA,2ALPHA,8BETA-TRIOL
- 8A,B-INDOLIZIDINE-1,2A,8B-TRIOL
- 8A,B-OCTAHYDROINDOLIZIDINE-1A,2A,8B-TRIOL
- swainsonine from locoweed
- swainsonine from rhizoctonia*leguminicola
- swainsonine synthetic
- SWAINSONINE FROM METARRHIZIUM ANISOPLIAE
- SWAINSONINE FROM RHIZOCTONIA &
- SWAINSONINE 98+%
- Tridolgosir
- (-)-D-Swainsonine
- (1S,2α,8β,8aβ)-Octahydro-1,2,8-indolizinetriol
- (1S,8aβ)-Octahydroindolizine-1α,2α,8β-triol
- D-Swainsonine
- (1S,2R,8R,8aR)-Octahydro-1,2,8-indolizinetriol
- SwainMoia
- 8a,-Octahydroindolizidine-1a,2a,8-triol
- SWAINSONINE, SWAINSONA CANESCENS
- 8-indolizinetriol(1s-(1-alpha,2-alpha,8-beta,8a-beta))-octahydro-2
- 8-indolizinetriol,octahydro-,(1s-(1-alpha,2-alpha,8-beta,8a-beta))-2
- (-)-SWAINSONINE
(1S,2R,8R,8AR)-1,2,8-OCTAHYDROINDOLIZIDINETRIOL
(1S,2S,8R,8AR)-TRIHYDROXYINDOLIZIDINE
- 8α,β-Octahydroindolizidine-1α,2α,8β-triol
- (1S,2R,8R,8aR)-1,2,3,5,6,7,8,8a-Octahydroindolizine-1,2,8-triol
- Swainsonine min. 99%
- 8AR)-1
- SWAINSONINE FROM LOCOWEED, 500 UG*
- SWAINSONINE
- Swainsonine, Swainsona canescens - CAS 72741-87-8 - Calbiochem
- 1,2,8-Indolizinetriol,octahydro-, (1S,2R,8R,8aR)-
- (-)-Swainsonine
- 72741-87-8
- Enzymes, Inhibitors, and Substrates
- Enzyme Inhibitors by Type
- Enzyme Inhibitors by Enzyme
- Enzyme Inhibitors
- L to O
- Mannosidase, alpha-
- Substrate Analogs
- BioChemical
- Biochemicals and Reagents
- Antibiotics
- Antibiotics N-S
- Antibiotics A to Z
- Alkaloids
- Glycosidase Inhibitors
- Inhibitors
- Elisa Kit-plant ELISA Kit
