N,N,N',N'-Tetramethylacridin-3,6-yldiaminhydrochlorid

ACRIDINE ORANGE Struktur
65-61-2
CAS-Nr.
65-61-2
Bezeichnung:
N,N,N',N'-Tetramethylacridin-3,6-yldiaminhydrochlorid
Englisch Name:
ACRIDINE ORANGE
Synonyma:
AO;AOX1;Lysotraker;CI NO 46005;BASIC ORANGE;-Cellstain-Ao;Euchrysine 3r;EUCHRYSINE 3RX;acridineoranger;RHODULINE ORANGE
CBNumber:
CB0747468
Summenformel:
C17H20ClN3
Molgewicht:
301.82
MOL-Datei:
65-61-2.mol

N,N,N',N'-Tetramethylacridin-3,6-yldiaminhydrochlorid Eigenschaften

Schmelzpunkt:
284-287 °C(lit.)
Dichte
1.001 g/mL at 20 °C
Brechungsindex
n20/D 1.338
storage temp. 
-20°C
Löslichkeit
Soluble in water, ethanol, dimethyl sulfoxide
Aggregatzustand
Powder
pka
-3.2, 10.5(at 25℃)
Colour Index 
46005
Farbe
orange to red
maximale Wellenlänge (λmax)
500 nm
BRN 
3734978
Biologische Anwendungen
Detecting cancer cells,spores,human papilloma virus (HPV),stress biomarkers; treating amyloid associated diseases,lupus,pathogen infections; apoptosis assays; cytotoxicity assays
Major Application
Adhesives; aluminophosphate crystalline materials; detecting clay particles; display device; evaluating fiber surface characteristics; glass matrixes; imaging material; inks; lasers; recording materials; photoresists; textiles; thin films; tracers for hydrology; wiring boards
CAS Datenbank
65-61-2
EPA chemische Informationen
C.I. Basic Orange 14 (65-61-2)
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
S-Sätze: 22-24/25
WGK Germany  3
RTECS-Nr. AR7601000
HS Code  32041300
Toxizität dnd-mus:ast 20 mmol/L BBACAQ 374,96,74
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H341 Kann vermutlich genetische Defekte verursachen. Keimzellmutagenität Kategorie 2 Warnung P201,P202, P281, P308+P313, P405,P501
Sicherheit
P201 Vor Gebrauch besondere Anweisungen einholen.
P202 Vor Gebrauch alle Sicherheitshinweise lesen und verstehen.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P308+P313 BEI Exposition oder falls betroffen: Ärztlichen Rat einholen/ärztliche Hilfe hinzuziehen.
P405 Unter Verschluss aufbewahren.
P501 Inhalt/Behälter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

N,N,N',N'-Tetramethylacridin-3,6-yldiaminhydrochlorid Chemische Eigenschaften,Einsatz,Produktion Methoden

S-Sätze Betriebsanweisung:

S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.

Chemische Eigenschaften

dark orange to brown powder

Verwenden

Acridine orange is a dye that interacts with DNA and RNA by intercelation or electrostatic attraction. This cationic dye has been used as a fluorescent stain for nucleic acids in agarose and polyacrylamide gels.

synthetische

4,4 ‘-Bis (N, N-dimethyl) aminodiphenylmethane obtained dinitration of 4,4′ – bis (N, N-dimethyl) amino-2 ‘- dinitro-diphenyl methane reduction, and with an acid of heat, so that the diamino compound is cyclized product is oxidized and then cyclized and converted into zinc chloride double salt.

Sicherheitsprofil

Mutation data reported. Whenheated to decomposition it emits very toxic fumes of HCl,Cl??, and NOx.

Enzyminhibitor

This cell-permeable dye (FWfree-base = 265.36 g/mol; CAS 65-61-2), also known as N,N,N',N'-tetramethylacridine-3,6-diamine, is an intercalator that binds tightly to nucleic acids. Binding to DNA is characterized by excitation maximum at 502 nm (cyan) and an emission maximum at 525 nm, producing a green fluorescence. (A 120 μM solution of acridine orange will detect 25-50 ng DNA per band in an agarose or polyacrylamide gel.) Binding to RNA is characterized by an excitation maximum at 460 nm and the emission maximum is located at 650 nm, yielding a reddish-orange fluorescence. Acridine orange also penetrates acidic compartments (e.g., lysosomes and phagolysosomes); upon protonation, the dye emits orange light when excited by blue light.

N,N,N',N'-Tetramethylacridin-3,6-yldiaminhydrochlorid Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


N,N,N',N'-Tetramethylacridin-3,6-yldiaminhydrochlorid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 133)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652
info@fdachem.com China 19368 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
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Hubei Jusheng Technology Co.,Ltd.
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+8618530059196
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TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 19892 58
GERBU Biotechnik GmbH
+49-62217264160 +49-62217264160
found@gerbu.de Germany 4 58
Nantong HI-FUTURE Biology Co., Ltd.
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Wuhan Topule Biopharmaceutical Co., Ltd
+8618327326525
masar@topule.com China 8474 58

65-61-2(N,N,N',N'-Tetramethylacridin-3,6-yldiaminhydrochlorid)Verwandte Suche:


  • 3,6-BIS(DIMETHYLAMINO)ACRIDINE HYDROCHLORIDE
  • ACRIDINE ORANGE (E GURR)
  • ACRIDINE ORANGE HYDROCHLORIDE
  • ACRIDINE ORANGE N
  • BASIC ORANGE
  • BIS(DIMETHYLAMINO) ACRIDINE HYDROCHLORIDE
  • AO
  • CI NO 46005
  • EUCHRYSINE 3RX
  • rhodulineorangeno
  • N,N,N',N'-tetramethylacridin-3,6-yldiamine hydrochloride
  • ACRIDINE ORANGE SOLUTION
  • ACRIDINE ORANGE HYDROCHLORIDE SOLUTION, ~1% IN WATER
  • ACRIDINE ORANGE FOR MICROSCOPY
  • ACRIDINE ORANGE HYDROCHLORIDE HYDRATE, F OR MICROSCOPY
  • ACRIDINE ORANGE HYDROCHLORIDE HYDRATE 80%
  • -Cellstain-Ao
  • -Cellstain-AoSolution
  • ACRIDING ORANGE HYDROCHLORIDE
  • 3,6-Bis(dimethylamino) acridine, zinc chloride double salt
  • Acridine Orange, hydrochloride hydrate, ca. 80 % dye content, pure
  • AOX1
  • acridine orange hydrochloride solution
  • 3,6-Bis(dimethylamino)acridine,hydrochloride,hydrate,aqueoussolution
  • ACRIDINE ORANGE N-HYRATE
  • Basic orange 14 (C.I. 46005)
  • Acridine Orange solution hydrochloride
  • Acridine Orange hydrate hydrochloride
  • Acridine Orange, hydrochloride hydrate,pure,ca. 80 % dye content
  • Acridine Orange hydrochloride solution,3,6-Bis(dimethylamino)acridine hydrochloride
  • ACRIDINE ORANGE HYDROCHLORIDE HYDRATE PURUM, FOR MICROSCOPY ((FL., HIST.)) 98%
  • RHODULINE ORANGE
  • 3,6-BIS(DIMETHYLAMINO)ACRIDINE, HCL
  • 3,6-acridinediamine, N,n,n0,n0-tetramethyl-, monohydrochloride
  • Acridine, 3,6-bis(dimethylamino)-, Hydrochloride
  • Acridine, 3,6-bis(dimethylamino)-, Monohydrochloride
  • Euchrysine 3r
  • Sumitomo Acridine Orange No
  • Sumitomo acridine Orange Rk Conc
  • 3,6-Acridinediamine,N,N,N’,N’-tetramethyl-,monohydrochloride
  • 3,6-bis(dimethylamino)-acridinmonohydrochloride
  • 6-acridinediamine,n,n,n’,n’-tetramethyl-monohydrochloride
  • acridineorangeno
  • acridineorangens
  • acridineoranger
  • c.i.basicorange14
  • 6-acridinediamine
  • 6-Bis(dimethylamino)acridine hydrochloride 3
  • Lysotraker
  • N’-Tetramethyl-3
  • N,N,N',N'-Tetramethyl-3,6-acridinediamine hydrochloride
  • N3,N3,N6,N6-Tetramethylacridine-3,6-diamine hydrochloride
  • Acridine Orange hydrochloride?, >99%
  • N3,N3,N6,N6-tetramethylacridine-3,6-diamine chloride
  • Cellstain AO Solution (1mg/ml H2O)
  • Acridine Orange Solution [for Cell Staining]
  • C.I.Basic Orange 14:C.I.46005
  • Acridine orange hydrochloride, hydrate, ≥98% (HPLC)
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