3,5-Dibrompyridin Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Chemische Eigenschaften
Light-Yellow Solid
Verwenden
3-Acetylamino-5-ethoxypyridine was prepared by converting 3, 5-dibromopyridine with sodium ethylate into 3-bromo-5-ethoxypyridine, allowing this substance to interact with ammonia and acetylating the aminoethoxypyridine thus formed with acetic anhydride. Lithiation of 3, 5-dibromopyridine with LDA and subsequent reaction with electrophiles provided 4-alkyl-3, 5-dibromopyridines 2 in high yield. Ligand was prepared by a Pd(0)-catalyzed cross-coupling reaction of 3,5-dibromopyridine and 5-tributylstannyl-3,3?-bipyridine. The synthesis of 3, 5-bis (2-indolyl) pyridine and 3-[(2-indolyl)-5-phenyl] pyridine derivatives as includes Stille or Suzuki type reactions, which were realized on the 3,5-dibromopyridine.
Application
3,5-Dibromopyridine (3,5-DBP) can be used for:
(1) Spectroscopic analysis: FTIR and FT Raman spectra in the solid phase of 3,5-DBP and 3,5- dichloro-2,4,6-trifluoropyridine (3,5-DCTFP) were recorded in the regions of 4000-400 cm-1 and 3500-100 cm-1, respectively
[1].
(2) Chemical reactions: 3,5-DBP can be reacted with phenyl isocyanate. chemoselective Staudinger-Phosphite reaction of 2,4,6-triazido-3,5-dibromopyridine azide moiety
[2-3].
(3) Organic synthesis: Using 3,5-dibromopyridine as raw material can be used to prepare 3-acetamido-5-ethoxypyridine
[4].
Allgemeine Beschreibung
3,5-Dibromopyridine undergoes lithiation with lithium diisopropylamide and on subsequent reaction with electrophiles yields 4-alkyl-3,5-dibromopyridines.
3,5-Dibrompyridin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
5-BROMO-2-FLUORO-3-METHOXYPYRIDINE
5-(BENZYLOXY)PYRIDIN-3-AMINE
3-Amino-5-hydroxypyridine
5-methoxypyridin-3-amine
3-(BENZYLOXY)-5-BROMOPYRIDINE
5-Bromopyridine-3-boronic acid
3-Amino-5-bromopyridine
3-Bromo-5-fluoropyridine
5-METHOXY-PYRIDINE-3-CARBALDEHYDE
3-BROMO-5-(METHYLTHIO)PYRIDINE
2-(5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl)propan-2-ol
4,6-Di(4-carboxyphenyl)pyrimidine
3-BroMo-5-(prop-1-en-2-yl)pyridine
3,5-Difluoro-4-pyridinecarboxaldehyde
3,5-Dibromo-4-cyanopyridine, 97%
3,5-DIBROMOPYRIDINE 1-OXIDE
5-BROMO-3-METHOXY-2-NITROPYRIDINE
3,5-Dimethoxypyridine
