PF 184

1187460-81-6

CAS-Nr.: 1187460-81-6

Englisch Name:: PF 184

Synonyma:: PF 184;8-[[[5-Chloro-2-[3,4-diMethyl-3,4-bis(hydroxyMethyl)-1-pyrrolidinyl]-4-pyridinyl]carbonyl]aMino]-1-(4-fluorophenyl)-4,5-dihydro-1H-benz[g]indazole-3-carboxaMide;1H-Benz[g]indazole-3-carboxamide, 8-[[[2-[3,4-bis(hydroxymethyl)-3,4-dimethyl-1-pyrrolidinyl]-5-chloro-4-pyridinyl]carbonyl]amino]-1-(4-fluorophenyl)-4,5-dihydro-

CBNumber:: CB22535689

Summenformel:: C32H32ClFN6O4

Molgewicht:: 619.09

MOL-Datei:: 1187460-81-6.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 30

PF 184 Eigenschaften

Siedepunkt:: 790.6±60.0 °C(Predicted)

Dichte: 1.47±0.1 g/cm3(Predicted)

storage temp.: Store at -20°C

Löslichkeit: Soluble to 100 mM in DMSO

Aggregatzustand: Powder

pka: 10.20±0.20(Predicted)

Sicherheit

PF 184 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

PF 184 is a potent and selective IKK-2 inhibitor (IC50 = 37 nM). Displays selectivity over 85 other kinases. Inhibits IL-1β-induced TNF-α in a steroid-insensitive in vitro model of oxidative stress.

PF 184 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

PF 184 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 30)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52927	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
Chemsky (shanghai) International Co.,Ltd	021-50135380	shchemsky@sina.com	China	15421	60
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8449	60
Shenzhen Polymeri Biochemical Technology Co., Ltd.	+86-400-002-6226 13028896684	sales@rrkchem.com	China	55954	58
MedBioPharmaceutical Technology Inc	021-69568360 18916172912	order@med-bio.cn	China	8141	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24017	58
Nantong QuanYi Biotechnology Co., Ltd	0513-66337626 18051384581	sales@chemhifuture.com	China	4209	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.com	China	24246	58

PF 184
8-[[[5-Chloro-2-[3,4-diMethyl-3,4-bis(hydroxyMethyl)-1-pyrrolidinyl]-4-pyridinyl]carbonyl]aMino]-1-(4-fluorophenyl)-4,5-dihydro-1H-benz[g]indazole-3-carboxaMide
1H-Benz[g]indazole-3-carboxamide, 8-[[[2-[3,4-bis(hydroxymethyl)-3,4-dimethyl-1-pyrrolidinyl]-5-chloro-4-pyridinyl]carbonyl]amino]-1-(4-fluorophenyl)-4,5-dihydro-
1187460-81-6
C32H32ClFN6O4
Amines
Aromatics
Heterocycles
Inhibitors
Intermediates & Fine Chemicals
Pfizer Compounds
Pharmaceuticals