5’O-Tritylinosine

5’O-Tritylinosine Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

KIN59 is a purine riboside derivative that allosterically inhibits thymidine phosphorylase (TPase; IC₅₀s = 44 and 67 μM for purified E. coli and human enzymes, respectively). Through this action, KIN59 blocks the conversion of thymidine to thymine. KIN59 inhibits TPase-induced angiogenesis in a chicken chorioallantoic membrane assay and reduces endothelial cell migration without impacting proliferation. KIN59 also inhibits the binding of fibroblast growth factor 2 (FGF2) to FGF receptor 1, preventing the growth and neovascularization of subcutaneous tumors induced by FGF2-transformed endothelial cells injected in immunodeficient nude mice.

Verwenden

5’O-Tritylinosine acts as an allosteric inhibitor of angiogenic enzyme thymidine phosphorylase.

5’O-Tritylinosine Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

5’O-Tritylinosine Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58
BOC Sciences	+16314854226	inquiry@bocsci.com	United States	19743	58
NewCan Biotech Limited	+86-0571-86912261 +8613735419629	sales@newcanbio.com	China	9980	58
Chemtour Biotech Co., Ltd	+8617327281506	market@chemtour.com	China	1472	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9709	58
Wuhu Huaren Science and Technology Co., Ltd.	0553-0553-5842013-801 18155347026	sale@huarensh.com	China	714	58
Shenzhen Polymeri Biochemical Technology Co., Ltd.	+86-400-002-6226 13028896684	sales@rrkchem.com	China	55954	58
Shanghai meikai technology co., ltd	021-18721550-091 18721550091	yangdong@pharma.com	China	4123	58
MedBioPharmaceutical Technology Inc	021-69568360 18916172912	order@med-bio.cn	China	8141	58

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• 5’O-Tritylinosine
• KIN-59
• Inosine, 5'-O-(triphenylmethyl)-
• 5'-O-tritylinosine-2'-deoxyinosine
• 5'-O-Trt-rI
• 4152-77-6